PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Transcription Factor Information
Basic Information? help Back to Top | |||||||||
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TF ID | Aqcoe2G438700.3.p | ||||||||
Common Name | AS2 | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; stem eudicotyledons; Ranunculales; Ranunculaceae; Thalictroideae; Aquilegia
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Family | LBD | ||||||||
Protein Properties | Length: 210aa MW: 22832.8 Da PI: 7.9005 | ||||||||
Description | LBD family protein | ||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | DUF260 | 147.6 | 3.4e-46 | 8 | 107 | 1 | 100 |
DUF260 1 aCaaCkvlrrkCakdCvlapyfpaeqpkkfanvhklFGasnvlkllkalpeeeredamsslvyeAearardPvyGavgvilklqqqleqlka 92 +CaaCk+lrrkC+++Cv+apyfp +qp+kfanvhk+FGasnv+kll++l++++reda++sl+yeA++r+rdPvyG+vgvi+ lq+ql+ql+ Aqcoe2G438700.3.p 8 PCAACKFLRRKCQPECVFAPYFPPDQPHKFANVHKVFGASNVTKLLNELHPHQREDAVNSLAYEADMRLRDPVYGCVGVISLLQRQLCQLQM 99 7******************************************************************************************* PP DUF260 93 elallkee 100 +l+ +k+e Aqcoe2G438700.3.p 100 DLSCAKSE 107 ***99987 PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
PROSITE profile | PS50891 | 27.342 | 7 | 108 | IPR004883 | Lateral organ boundaries, LOB |
Pfam | PF03195 | 4.6E-45 | 8 | 105 | IPR004883 | Lateral organ boundaries, LOB |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0009799 | Biological Process | specification of symmetry | ||||
GO:0009944 | Biological Process | polarity specification of adaxial/abaxial axis | ||||
GO:0009954 | Biological Process | proximal/distal pattern formation | ||||
GO:0048441 | Biological Process | petal development | ||||
GO:0005654 | Cellular Component | nucleoplasm |
Sequence ? help Back to Top |
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Protein Sequence Length: 210 aa Download sequence Send to blast |
MASSSTSPCA ACKFLRRKCQ PECVFAPYFP PDQPHKFANV HKVFGASNVT KLLNELHPHQ 60 REDAVNSLAY EADMRLRDPV YGCVGVISLL QRQLCQLQMD LSCAKSELSK YQNVGLTGHG 120 LIAAAAAAHP HMGISLLTGP DHHHHHHHQF LISRDHQQTL RSFDINGGAA YDHSSLIAAM 180 NVSTNIGPAL AQFQQQPRTA GGDDRLGPS* |
3D Structure ? help Back to Top | ||||||
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PDB ID | Evalue | Query Start | Query End | Hit Start | Hit End | Description |
5ly0_A | 2e-55 | 7 | 118 | 10 | 121 | LOB family transfactor Ramosa2.1 |
5ly0_B | 2e-55 | 7 | 118 | 10 | 121 | LOB family transfactor Ramosa2.1 |
Search in ModeBase |
Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | Negative regulator of cell proliferation in the adaxial side of leaves. Regulates the formation of a symmetric lamina and the establishment of venation. Positively regulates LATERAL ORGAN BOUNDARIES (LOB) within the shoot apex, and the class III HD-ZIP genes REV, PHB, and PHV. Interacts directly with ASYMMETRIC LEAVES 1 (AS1) to repress the knox homeobox genes KNAT1, KNAT2, and KNAT6 and the abaxial determinants ARF3, KAN2 and YAB5. May act in parallel with the RDR6-SGS3-AGO7 pathway, an endogenous RNA silencing pathway, to regulate the leaf morphogenesis (PubMed:11311158, PubMed:12787254, PubMed:12874130, PubMed:14508003, PubMed:16006579, PubMed:16699177, PubMed:17395603, PubMed:17559509). Required for the binding of AS1 to the KNOX genes (PubMed:23271976). Involved in leaf polarity establishment by functioning cooperatively with RH10 or RID2 to repress abaxial genes ARF3, ARF4, KAN1, KAN2, YAB1 and YAB5, and the knox homeobox genes KNAT1, KNAT2, KNAT6, and STM to promote adaxial development in leaf primordia at shoot apical meristems at high temperatures (PubMed:27334696). {ECO:0000269|PubMed:11311158, ECO:0000269|PubMed:12787254, ECO:0000269|PubMed:12874130, ECO:0000269|PubMed:14508003, ECO:0000269|PubMed:16006579, ECO:0000269|PubMed:16699177, ECO:0000269|PubMed:17395603, ECO:0000269|PubMed:17559509, ECO:0000269|PubMed:23271976, ECO:0000269|PubMed:27334696}. |
Binding Motif ? help Back to Top | |||
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Motif ID | Method | Source | Motif file |
MP00211 | DAP | Transfer from AT1G65620 | Download |
Regulation -- Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | INDUCTION: Negatively regulated by SHOOT MERISTEMLESS (STM). {ECO:0000269|PubMed:11934861}. |
Regulation -- PlantRegMap ? help Back to Top | ||||||
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Source | Upstream Regulator | Target Gene | ||||
PlantRegMap | Retrieve | Retrieve |
Annotation -- Nucleotide ? help Back to Top | ||||||
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Source | Hit ID | E-value | Description | |||
GenBank | KC854333 | 0.0 | KC854333.1 Aquilegia coerulea AS2 (AS2) mRNA, complete cds. |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | XP_026423718.1 | 1e-104 | protein ASYMMETRIC LEAVES 2-like | ||||
Refseq | XP_026423724.1 | 1e-104 | protein ASYMMETRIC LEAVES 2-like | ||||
Swissprot | O04479 | 2e-76 | AS2_ARATH; Protein ASYMMETRIC LEAVES 2 | ||||
TrEMBL | S5N014 | 1e-153 | S5N014_AQUCA; AS2 | ||||
STRING | Aquca_058_00006.1 | 1e-154 | (Aquilegia coerulea) |
Best hit in Arabidopsis thaliana ? help Back to Top | ||||||
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Hit ID | E-value | Description | ||||
AT1G65620.4 | 1e-72 | LBD family protein |
Link Out ? help Back to Top | |
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Phytozome | Aqcoe2G438700.3.p |