PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AA46G00124
Organism
Aethionema arabicum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Aethionemeae; Aethionema
Family CAMTA
Protein Properties Length: 998aa    MW: 112716 Da    PI: 5.7137
Description CAMTA family protein
Gene Model
Gene Model ID Type Source Coding Sequence
AA46G00124genomeVEGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1CG-1181.97.1e-57201363118
        CG-1   3 ke.kkrwlkneeiaaiLenfekheltlelktrpksgsliLynrkkvryfrkDGyswkkkkdgktvrEdhekLKvggvevlycyYahseenptfqrrcyw 100
                 +e ++rwl++ ei++iL+n++++++++e++t+p+sgs++L++rk++ryfrkDG++w+kk+dgktv+E+he+LK g+++vl+cyYah+e+n++fqrr+yw
  AA46G00124  20 SEaRHRWLRAPEICEILQNYQRFQISTEPPTTPSSGSVFLFDRKVLRYFRKDGHNWRKKRDGKTVKEAHERLKAGSIDVLHCYYAHGEDNENFQRRSYW 118
                 4449*********************************************************************************************** PP

        CG-1 101 lLeeelekivlvhylevk 118
                 +L+eel++iv+vhylevk
  AA46G00124 119 MLQEELSHIVFVHYLEVK 136
                 ***************985 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5143781.88615141IPR005559CG-1 DNA-binding domain
SMARTSM010768.6E-8418136IPR005559CG-1 DNA-binding domain
PfamPF038593.3E-4921135IPR005559CG-1 DNA-binding domain
Gene3DG3DSA:2.60.40.100.001433520IPR013783Immunoglobulin-like fold
SuperFamilySSF812964.06E-14433521IPR014756Immunoglobulin E-set
PfamPF018331.2E-4433520IPR002909IPT domain
PROSITE profilePS5029715.671603712IPR020683Ankyrin repeat-containing domain
SuperFamilySSF484031.55E-14611715IPR020683Ankyrin repeat-containing domain
Gene3DG3DSA:1.25.40.203.2E-14614717IPR020683Ankyrin repeat-containing domain
CDDcd002041.65E-10615715No hitNo description
PfamPF000234.5E-4653683IPR002110Ankyrin repeat
PROSITE profilePS500889.591653685IPR002110Ankyrin repeat
SuperFamilySSF525403.45E-7813868IPR027417P-loop containing nucleoside triphosphate hydrolase
SMARTSM000150.4817839IPR000048IQ motif, EF-hand binding site
PROSITE profilePS500969.139819847IPR000048IQ motif, EF-hand binding site
PfamPF006120.0019820838IPR000048IQ motif, EF-hand binding site
SMARTSM000150.026840862IPR000048IQ motif, EF-hand binding site
PROSITE profilePS500969.395841865IPR000048IQ motif, EF-hand binding site
PfamPF006120.0016843862IPR000048IQ motif, EF-hand binding site
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0009409Biological Processresponse to cold
GO:0010150Biological Processleaf senescence
GO:0042742Biological Processdefense response to bacterium
GO:0050832Biological Processdefense response to fungus
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0005516Molecular Functioncalmodulin binding
Sequence ? help Back to Top
Protein Sequence    Length: 998 aa     Download sequence    Send to blast
MAEARRFSPV NDLDVGQILS EARHRWLRAP EICEILQNYQ RFQISTEPPT TPSSGSVFLF  60
DRKVLRYFRK DGHNWRKKRD GKTVKEAHER LKAGSIDVLH CYYAHGEDNE NFQRRSYWML  120
QEELSHIVFV HYLEVKGSRV STSYNRIQRS EDASPQSYQE NGEILFSERS NHSQTTGSGS  180
VNGVHTPELE DAQSAYNQQA SPIVYQHQEL QYPQNKAALA GFDPYYHQMS FSTKGLRAIP  240
VMDSSTMVDK TKSINNVGDR DSIETQTWEE ILGNCGSGVE TLVLQQNNNE QEVLDQLLQS  300
CSYTDQDFVN LQDHEFNSRF ASDRPAWFDG QDLEQSGLTS NAIASCPSTM KQHLLDSTVG  360
EDGLKKMDSF NRWMSKELGD VGVIADANES FTHSSSRTYW EEVENEDGSN GSKGDLDGYV  420
MSPSLSKEQL FSIIDFSPSW AYVGCQVKVI ITGKFLKNQE EAETCKWSCM FGQTEVPAQV  480
ISSNGVLRCI APVHESVRRI PFYVTCSNRL ACSEVREFEY RIQSEEEEES PCSSIESLEA  540
RFVKLLCSNK SDSTMSRNDN NSDLSQRISL LLFENDDEII SEESTKKNRV LQEDLKEWLR  600
LWLLQRVGEG GKGANVLDEG GQGVLHFAAA LGYNWGLEPT VIAGVSVDFR DVNGWTALHW  660
AAFFGRERII GSLIALGASP GTLTDPNPDF PSGSTPSDLA YANGHKGIAG YLSEYALRSH  720
VSLLSLNETN QETSLGVTIP SPSTTSSLTD SLTAVRNATQ AAARIHQVFR AQSFQKKQIK  780
EFGDTRFGMS DERALSLLAI KGHKTGRHHH NSHSDDSVQA AAIRIQNKFR GYKGRKEYLI  840
TRQRIIKLQA LVRGHQVRKN YRKIIWSVGI LEKVILRWRR KGHGLRGFKS DALIDKMQDG  900
TEKEEDDDFF KEGRKQTEER LQKALARVKS MVQYPEARDQ YRRLLNVVNE IQESKVEKAL  960
ANSEANCFDD DDLIDIEALL GDDDTLMLPM VSSALWTT
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds to the DNA consensus sequence 5'-[ACG]CGCG[GTC]-3'. Binds calmodulin in a calcium-dependent manner in vitro (PubMed:12218065). Regulates transcriptional activity in response to calcium signals (Probable). Involved in freezing tolerance in association with CAMTA1 and CAMTA2 (PubMed:23581962). Required for the cold-induced expression of DREB1B/CBF1, DREB1C/CBF2, ZAT12 and GOLS3 (PubMed:19270186). Involved in response to cold. Contributes together with CAMTA5 to the positive regulation of the cold-induced expression of DREB1A/CBF3, DREB1B/CBF1 and DREB1C/CBF2 (PubMed:28351986). Involved together with CAMTA2 and CAMTA4 in the positive regulation of a general stress response (GSR) (PubMed:25039701). Involved in the regulation of GSR amplitude downstream of MEKK1 (PubMed:25157030). Involved in the regulation of a set of genes involved in defense responses against pathogens (PubMed:18298954). Involved in the regulation of both basal resistance and systemic acquired resistance (SAR) (PubMed:21900483). Acts as negative regulator of plant immunity (PubMed:19122675, PubMed:21900483, PubMed:22345509, PubMed:28407487). Binds to the promoter of the defense-related gene EDS1 and represses its expression (PubMed:19122675). Binds to the promoter of the defense-related gene NDR1 and represses its expression (PubMed:22345509). Involved in defense against insects (PubMed:23072934, PubMed:22371088). Required for tolerance to the generalist herbivore Trichoplusia ni, and contributes to the positive regulation of genes associated with glucosinolate metabolism (PubMed:23072934). Required for tolerance to Bradysia impatiens larvae. Mediates herbivore-induced wound response (PubMed:22371088). Required for wound-induced jasmonate accumulation (PubMed:23072934, PubMed:22371088). Involved in the regulation of ethylene-induced senescence by binding to the promoter of the senescence-inducer gene EIN3 and repressing its expression (PubMed:22345509). {ECO:0000269|PubMed:12218065, ECO:0000269|PubMed:18298954, ECO:0000269|PubMed:19122675, ECO:0000269|PubMed:19270186, ECO:0000269|PubMed:21900483, ECO:0000269|PubMed:22345509, ECO:0000269|PubMed:22371088, ECO:0000269|PubMed:23072934, ECO:0000269|PubMed:23581962, ECO:0000269|PubMed:25039701, ECO:0000269|PubMed:25157030, ECO:0000269|PubMed:28351986, ECO:0000269|PubMed:28407487, ECO:0000305|PubMed:11925432}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00042PBMTransfer from AT2G22300Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapAA46G00124
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By heat shock, UVB, salt, wounding, ethylene and methyl jasmonate (PubMed:11162426, PubMed:12218065). Induced by infection with the fungal pathogen Golovinomyces cichoracearum (powdery mildew) and the bacterial pathogen Pseudomonas syringae pv tomato strain DC3000 (PubMed:22345509). {ECO:0000269|PubMed:11162426, ECO:0000269|PubMed:12218065, ECO:0000269|PubMed:22345509}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_024014331.10.0calmodulin-binding transcription activator 3 isoform X2
SwissprotQ8GSA70.0CMTA3_ARATH; Calmodulin-binding transcription activator 3
TrEMBLV4L6Z90.0V4L6Z9_EUTSA; Uncharacterized protein
TrEMBLV4LQS40.0V4LQS4_EUTSA; Uncharacterized protein
STRINGXP_006404687.10.0(Eutrema salsugineum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM86012535
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G22300.20.0signal responsive 1
Publications ? help Back to Top
  1. Zhang L,Du L,Shen C,Yang Y,Poovaiah BW
    Regulation of plant immunity through ubiquitin-mediated modulation of Ca(2+) -calmodulin-AtSR1/CAMTA3 signaling.
    Plant J., 2014. 78(2): p. 269-81
    [PMID:24528504]
  2. Benn G, et al.
    A key general stress response motif is regulated non-uniformly by CAMTA transcription factors.
    Plant J., 2014. 80(1): p. 82-92
    [PMID:25039701]
  3. Rahman H,Yang J,Xu YP,Munyampundu JP,Cai XZ
    Phylogeny of Plant CAMTAs and Role of AtCAMTAs in Nonhost Resistance to Xanthomonas oryzae pv. oryzae.
    Front Plant Sci, 2016. 7: p. 177
    [PMID:26973658]
  4. Benn G, et al.
    Plastidial metabolite MEcPP induces a transcriptionally centered stress-response hub via the transcription factor CAMTA3.
    Proc. Natl. Acad. Sci. U.S.A., 2016. 113(31): p. 8855-60
    [PMID:27432993]
  5. Kidokoro S, et al.
    Different Cold-Signaling Pathways Function in the Responses to Rapid and Gradual Decreases in Temperature.
    Plant Cell, 2017. 29(4): p. 760-774
    [PMID:28351986]
  6. Lolle S, et al.
    Matching NLR Immune Receptors to Autoimmunity in camta3 Mutants Using Antimorphic NLR Alleles.
    Cell Host Microbe, 2017. 21(4): p. 518-529.e4
    [PMID:28407487]
  7. Kim YS, et al.
    CAMTA-Mediated Regulation of Salicylic Acid Immunity Pathway Genes in Arabidopsis Exposed to Low Temperature and Pathogen Infection.
    Plant Cell, 2017. 29(10): p. 2465-2477
    [PMID:28982964]
  8. Jacob F, et al.
    A dominant-interfering camta3 mutation compromises primary transcriptional outputs mediated by both cell surface and intracellular immune receptors in Arabidopsis thaliana.
    New Phytol., 2018. 217(4): p. 1667-1680
    [PMID:29226970]