PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

AA11G00058

Organism

Aethionema arabicum

Taxonomic ID

228871

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Aethionemeae; Aethionema

Family

NAC

Protein Properties

Length: 349aa MW: 38689.2 Da PI: 8.8736

Description

NAC family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
AA11G00058	genome	VEGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	NAM	178.4	1.9e-55	19	147	1	129
NAM 1 lppGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLpkkvkaeekewyfFskrdkkyatgkrknratksgyWkatgkdkevlsk.kge 98 lppGfrFhPtdeel+++yL +kv + ++ ++i+evd++k+ePw+Lp k+k +ekewyfFs rd+ky+tg r+nrat++gyWkatgkd+e++s+ + + AA11G00058 19 LPPGFRFHPTDEELITHYLLRKVLDGCFTS-RAIAEVDLNKCEPWQLPGKAKMGEKEWYFFSLRDRKYPTGLRTNRATEAGYWKATGKDREIYSSkTCA 116 79***********************999.89***********99999************************************974556 PP NAM 99 lvglkktLvfykgrapkgektdWvmheyrle 129 lvg+kktLvfykgrapkgek++Wvmheyrle AA11G00058 117 LVGMKKTLVFYKGRAPKGEKSNWVMHEYRLE 147 7**************************85 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF101941	3.14E-63	14	171	IPR003441	NAC domain
PROSITE profile	PS51005	59.765	19	171	IPR003441	NAC domain
Pfam	PF02365	4.5E-29	20	146	IPR003441	NAC domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0010072	Biological Process	primary shoot apical meristem specification
GO:0010160	Biological Process	formation of organ boundary
GO:0010223	Biological Process	secondary shoot formation
GO:0048366	Biological Process	leaf development
GO:0048504	Biological Process	regulation of timing of organ formation
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 349 aa Download sequence Send to blast
MDIACYQYDH GGAGDGQYLP PGFRFHPTDE ELITHYLLRK VLDGCFTSRA IAEVDLNKCE 60 PWQLPGKAKM GEKEWYFFSL RDRKYPTGLR TNRATEAGYW KATGKDREIY SSKTCALVGM 120 KKTLVFYKGR APKGEKSNWV MHEYRLEGKF SYHFISRSSK DEWVISRVFQ KSGIGSNSNG 180 VTVASVGVGK KTKIPSEQQQ QLKQPSSPSS SVSLPPLLPV GSSLDNSSCS YDTSRSTDQH 240 VSCFSTASLG SLDSFNHLLP PPQTLGFDPF QRFVSRNGGV SNLSNFKAFQ ESSHYFGSSS 300 VSTSLSAVNL SSSSSSSQSG VNYWLPATAE ENETKASLIH TGIDYLWNY

Sequence ? help Back to Top

Protein Sequence Length: 349 aa Download sequence Send to blast

MDIACYQYDH GGAGDGQYLP PGFRFHPTDE ELITHYLLRK VLDGCFTSRA IAEVDLNKCE  60
PWQLPGKAKM GEKEWYFFSL RDRKYPTGLR TNRATEAGYW KATGKDREIY SSKTCALVGM  120
KKTLVFYKGR APKGEKSNWV MHEYRLEGKF SYHFISRSSK DEWVISRVFQ KSGIGSNSNG  180
VTVASVGVGK KTKIPSEQQQ QLKQPSSPSS SVSLPPLLPV GSSLDNSSCS YDTSRSTDQH  240
VSCFSTASLG SLDSFNHLLP PPQTLGFDPF QRFVSRNGGV SNLSNFKAFQ ESSHYFGSSS  300
VSTSLSAVNL SSSSSSSQSG VNYWLPATAE ENETKASLIH TGIDYLWNY

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1ut4_A	2e-52	19	171	17	165	NO APICAL MERISTEM PROTEIN
1ut4_B	2e-52	19	171	17	165	NO APICAL MERISTEM PROTEIN
1ut7_A	2e-52	19	171	17	165	NO APICAL MERISTEM PROTEIN
1ut7_B	2e-52	19	171	17	165	NO APICAL MERISTEM PROTEIN
4dul_A	2e-52	19	171	17	165	NAC domain-containing protein 19
4dul_B	2e-52	19	171	17	165	NAC domain-containing protein 19
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator of STM and KNAT6. Involved in molecular mechanisms regulating shoot apical meristem (SAM) formation during embryogenesis and organ separation. Required for the fusion of septa of gynoecia along the length of the ovaries. Activates the shoot formation in callus in a STM-dependent manner. Controls leaf margin development and required for leaf serration. Involved in axillary meristem initiation and separation of the meristem from the main stem. Regulates the phyllotaxy throughout the plant development. Seems to act as an inhibitor of cell division. {ECO:0000269\|PubMed:10079219, ECO:0000269\|PubMed:10750709, ECO:0000269\|PubMed:12163400, ECO:0000269\|PubMed:12492830, ECO:0000269\|PubMed:12610213, ECO:0000269\|PubMed:15202996, ECO:0000269\|PubMed:15294871, ECO:0000269\|PubMed:15500463, ECO:0000269\|PubMed:15723790, ECO:0000269\|PubMed:16798887, ECO:0000269\|PubMed:17098808, ECO:0000269\|PubMed:17122068, ECO:0000269\|PubMed:17251269, ECO:0000269\|PubMed:17287247, ECO:0000269\|PubMed:9212461}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00562	DAP	Transfer from AT5G53950	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	AA11G00058

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By BRM and SYD, at the chromatin level, and conferring a very specific spatial expression pattern. Precise spatial regulation by post-transcriptional repression directed by the microRNA miR164. {ECO:0000269\|PubMed:15202996, ECO:0000269\|PubMed:15294871, ECO:0000269\|PubMed:15723790, ECO:0000269\|PubMed:16854978, ECO:0000269\|PubMed:17251269, ECO:0000269\|PubMed:17287247}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006282084.1	1e-162	protein CUP-SHAPED COTYLEDON 2
Swissprot	O04017	1e-161	NAC98_ARATH; Protein CUP-SHAPED COTYLEDON 2
TrEMBL	A0A087GAV9	1e-162	A0A087GAV9_ARAAL; Uncharacterized protein
STRING	A0A087GAV9	1e-163	(Arabis alpina)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM6615	27	45

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G53950.1	1e-152	NAC family protein

Publications ? help Back to Top
Wang YX Characterization of a novel Medicago sativa NAC transcription factor gene involved in response to drought stress. Mol. Biol. Rep., 2013. 40(11): p. 6451-8 [PMID:24057250] Kamiuchi Y,Yamamoto K,Furutani M,Tasaka M,Aida M The CUC1 and CUC2 genes promote carpel margin meristem formation during Arabidopsis gynoecium development. Front Plant Sci, 2014. 5: p. 165 [PMID:24817871] Gonçalves B, et al. A conserved role for CUP-SHAPED COTYLEDON genes during ovule development. Plant J., 2015. 83(4): p. 732-42 [PMID:26119568] Du Q,Wang H The role of HD-ZIP III transcription factors and miR165/166 in vascular development and secondary cell wall formation. Plant Signal Behav, 2015. 10(10): p. e1078955 [PMID:26340415] Vialette-Guiraud AC, et al. A Conserved Role for the NAM/miR164 Developmental Module Reveals a Common Mechanism Underlying Carpel Margin Fusion in Monocarpous and Syncarpous Eurosids. Front Plant Sci, 2015. 6: p. 1239 [PMID:26793217] Cui X, et al. REF6 recognizes a specific DNA sequence to demethylate H3K27me3 and regulate organ boundary formation in Arabidopsis. Nat. Genet., 2016. 48(6): p. 694-9 [PMID:27111035] Blein T,Pautot V,Laufs P Combinations of Mutations Sufficient to Alter Arabidopsis Leaf Dissection. Plants (Basel), 2013. 2(2): p. 230-47 [PMID:27137374] Biot E, et al. Multiscale quantification of morphodynamics: MorphoLeaf software for 2D shape analysis. Development, 2016. 143(18): p. 3417-28 [PMID:27387872] Zheng M, et al. Chloroplast Translation Initiation Factors Regulate Leaf Variegation and Development. Plant Physiol., 2016. 172(2): p. 1117-1130 [PMID:27535792] Balkunde R,Kitagawa M,Xu XM,Wang J,Jackson D SHOOT MERISTEMLESS trafficking controls axillary meristem formation, meristem size and organ boundaries in Arabidopsis. Plant J., 2017. 90(3): p. 435-446 [PMID:28161901] Koyama T,Sato F,Ohme-Takagi M Roles of miR319 and TCP Transcription Factors in Leaf Development. Plant Physiol., 2017. 175(2): p. 874-885 [PMID:28842549] González-Carranza ZH, et al. HAWAIIAN SKIRT controls size and floral organ number by modulating CUC1 and CUC2 expression. PLoS ONE, 2017. 12(9): p. e0185106 [PMID:28934292] Wilson-Sánchez D,Martínez-López S,Navarro-Cartagena S,Jover-Gil S,Micol JL Members of the DEAL subfamily of the DUF1218 gene family are required for bilateral symmetry but not for dorsoventrality in Arabidopsis leaves. New Phytol., 2018. 217(3): p. 1307-1321 [PMID:29139551] Gonçalves B, et al. GDP-L-fucose is required for boundary definition in plants. J. Exp. Bot., 2017. 68(21-22): p. 5801-5811 [PMID:29186469] Sha S, et al. To be serrate or pinnate: diverse leaf forms of yarrows (Achillea) are linked to differential expression patterns of NAM genes. Ann. Bot., 2018. 121(2): p. 255-266 [PMID:29267935] Maugarny-Calès A, et al. Dissecting the pathways coordinating patterning and growth by plant boundary domains. PLoS Genet., 2019. 15(1): p. e1007913 [PMID:30677017]