PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

KFK32837.1

Organism

Arabis alpina

Taxonomic ID

50452

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Arabideae; Arabis

Family

CAMTA

Protein Properties

Length: 1034aa MW: 116536 Da PI: 5.257

Description

CAMTA family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
KFK32837.1	genome	MPIPBR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	CG-1	180.9	1.5e-56	20	136	3	118
CG-1 3 ke.kkrwlkneeiaaiLenfekheltlelktrpksgsliLynrkkvryfrkDGyswkkkkdgktvrEdhekLKvggvevlycyYahseenptfqrrcyw 100 +e ++rwl++ ei++iL+n++++++++e++t+p+sgs++L++rk++ryfrkDG++w+kk+dgktv+E+he+LK g+v+vl+cyYah+++n++fqrr+yw KFK32837.1 20 SEaRNRWLRPPEICEILQNYQRFQISTEPPTTPSSGSVFLFDRKVLRYFRKDGHNWRKKRDGKTVKEAHERLKAGSVDVLHCYYAHGQDNENFQRRSYW 118 4449********************************************************************************************* PP CG-1 101 lLeeelekivlvhylevk 118 +L+eel++iv+vhylevk KFK32837.1 119 MLQEELSNIVFVHYLEVK 136 *************985 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51437	82.079	15	141	IPR005559	CG-1 DNA-binding domain
SMART	SM01076	7.8E-84	18	136	IPR005559	CG-1 DNA-binding domain
Pfam	PF03859	3.8E-49	21	135	IPR005559	CG-1 DNA-binding domain
SuperFamily	SSF81296	2.49E-16	463	548	IPR014756	Immunoglobulin E-set
PROSITE profile	PS50297	16.441	626	752	IPR020683	Ankyrin repeat-containing domain
Gene3D	G3DSA:1.25.40.20	1.5E-14	626	755	IPR020683	Ankyrin repeat-containing domain
SuperFamily	SSF48403	7.15E-15	638	755	IPR020683	Ankyrin repeat-containing domain
CDD	cd00204	1.37E-10	640	752	No hit	No description
PROSITE profile	PS50088	8.71	693	725	IPR002110	Ankyrin repeat
SuperFamily	SSF52540	6.9E-8	853	905	IPR027417	P-loop containing nucleoside triphosphate hydrolase
SMART	SM00015	0.4	854	876	IPR000048	IQ motif, EF-hand binding site
PROSITE profile	PS50096	9.139	856	884	IPR000048	IQ motif, EF-hand binding site
Pfam	PF00612	0.002	857	875	IPR000048	IQ motif, EF-hand binding site
SMART	SM00015	0.023	877	899	IPR000048	IQ motif, EF-hand binding site
PROSITE profile	PS50096	9.048	878	902	IPR000048	IQ motif, EF-hand binding site
Pfam	PF00612	7.8E-4	880	899	IPR000048	IQ motif, EF-hand binding site

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009409	Biological Process	response to cold
GO:0010150	Biological Process	leaf senescence
GO:0042742	Biological Process	defense response to bacterium
GO:0050832	Biological Process	defense response to fungus
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0005516	Molecular Function	calmodulin binding

Sequence ? help Back to Top
Protein Sequence Length: 1034 aa Download sequence Send to blast
MAEARRFSPN HELDVEQILS EARNRWLRPP EICEILQNYQ RFQISTEPPT TPSSGSVFLF 60 DRKVLRYFRK DGHNWRKKRD GKTVKEAHER LKAGSVDVLH CYYAHGQDNE NFQRRSYWML 120 QEELSNIVFV HYLEVKGSRV STSYNRMQRT EDAVRSPQET GEVLTSERDG YASYSINQYD 180 HSNHSHATDS ASVNGVHTPE LEDVESAYNQ QANSIVYSHQ EFQQPATTGF DPYYQMTLTP 240 ARDSYRKELR TIPVIDSSIM VDRSKTINGP GVANGLRNKK SIDSQSWEEI LGNCGSGTEG 300 LPMQPNSKNE VLDEMLQSSA FTMQDFASLQ ESMVKSQNQE LHPGLASDRT VWFEGQDMEL 360 NTISNLASNE KAPYLSTMKQ HLLDGALGEE GLKKMDSFNR WMSKELGDVG VIADANESFT 420 QSSSRTYWEE VESEDGSNGH NSRRDLDGYV MSPSLSKEQF FSIIDFSPSW TYVGCEVQVL 480 VTGKFLKTRE EAEIGEWSCM FGQTEVRADV IANGVLQCVA PMHEAGRVPF YVTCSNRLAC 540 SEVREFEYKV VESQVFDRET DESTTIGILE ARFIKLLCSK SDCPSASLSG NDSDLSQVSQ 600 KISLLLFEND DQLDQMLMNE ISQENMKNNL LRDALKESLH SWLLQKIAEG GKGPNVLDEG 660 GQGILHFAAA LGYNWALEPT IVAGVSVDFR DVNGWTALHW AAFFGRELVI GSLIALGAAP 720 GTLTDPNPDF PSGSTPSDLA YANGYKGIAG YLSEYALRAH LSLLSLNDKN AESPLAAVET 780 APSPSSSSLT DSLTAVRNAT QAAARIHQVF RAQSFQKKQI KEFGDRKFGM SEERALSMLA 840 PKTHKPGRAH SDDSVQAAAI RIQNKFRGYK GRKEYLITRQ RIIKIQAHVR GYQFRKNYRK 900 IVWSVGILEK VILRWKRKGA GLRGFKSEAL VDKMQDGTEK EEDDDFFKQG RKQTEERLEK 960 ALARVKSMVQ YPEARDQYRR LLNVVNDIQE SKVEKALDSS EDAICFDDDL IDIESLLEDD 1020 ETLMLPMSST MWAS

Sequence ? help Back to Top

Protein Sequence Length: 1034 aa Download sequence Send to blast

MAEARRFSPN HELDVEQILS EARNRWLRPP EICEILQNYQ RFQISTEPPT TPSSGSVFLF  60
DRKVLRYFRK DGHNWRKKRD GKTVKEAHER LKAGSVDVLH CYYAHGQDNE NFQRRSYWML  120
QEELSNIVFV HYLEVKGSRV STSYNRMQRT EDAVRSPQET GEVLTSERDG YASYSINQYD  180
HSNHSHATDS ASVNGVHTPE LEDVESAYNQ QANSIVYSHQ EFQQPATTGF DPYYQMTLTP  240
ARDSYRKELR TIPVIDSSIM VDRSKTINGP GVANGLRNKK SIDSQSWEEI LGNCGSGTEG  300
LPMQPNSKNE VLDEMLQSSA FTMQDFASLQ ESMVKSQNQE LHPGLASDRT VWFEGQDMEL  360
NTISNLASNE KAPYLSTMKQ HLLDGALGEE GLKKMDSFNR WMSKELGDVG VIADANESFT  420
QSSSRTYWEE VESEDGSNGH NSRRDLDGYV MSPSLSKEQF FSIIDFSPSW TYVGCEVQVL  480
VTGKFLKTRE EAEIGEWSCM FGQTEVRADV IANGVLQCVA PMHEAGRVPF YVTCSNRLAC  540
SEVREFEYKV VESQVFDRET DESTTIGILE ARFIKLLCSK SDCPSASLSG NDSDLSQVSQ  600
KISLLLFEND DQLDQMLMNE ISQENMKNNL LRDALKESLH SWLLQKIAEG GKGPNVLDEG  660
GQGILHFAAA LGYNWALEPT IVAGVSVDFR DVNGWTALHW AAFFGRELVI GSLIALGAAP  720
GTLTDPNPDF PSGSTPSDLA YANGYKGIAG YLSEYALRAH LSLLSLNDKN AESPLAAVET  780
APSPSSSSLT DSLTAVRNAT QAAARIHQVF RAQSFQKKQI KEFGDRKFGM SEERALSMLA  840
PKTHKPGRAH SDDSVQAAAI RIQNKFRGYK GRKEYLITRQ RIIKIQAHVR GYQFRKNYRK  900
IVWSVGILEK VILRWKRKGA GLRGFKSEAL VDKMQDGTEK EEDDDFFKQG RKQTEERLEK  960
ALARVKSMVQ YPEARDQYRR LLNVVNDIQE SKVEKALDSS EDAICFDDDL IDIESLLEDD  1020
ETLMLPMSST MWAS

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds to the DNA consensus sequence 5'-[ACG]CGCG[GTC]-3'. Binds calmodulin in a calcium-dependent manner in vitro (PubMed:12218065). Regulates transcriptional activity in response to calcium signals (Probable). Involved in freezing tolerance in association with CAMTA1 and CAMTA2 (PubMed:23581962). Required for the cold-induced expression of DREB1B/CBF1, DREB1C/CBF2, ZAT12 and GOLS3 (PubMed:19270186). Involved in response to cold. Contributes together with CAMTA5 to the positive regulation of the cold-induced expression of DREB1A/CBF3, DREB1B/CBF1 and DREB1C/CBF2 (PubMed:28351986). Involved together with CAMTA2 and CAMTA4 in the positive regulation of a general stress response (GSR) (PubMed:25039701). Involved in the regulation of GSR amplitude downstream of MEKK1 (PubMed:25157030). Involved in the regulation of a set of genes involved in defense responses against pathogens (PubMed:18298954). Involved in the regulation of both basal resistance and systemic acquired resistance (SAR) (PubMed:21900483). Acts as negative regulator of plant immunity (PubMed:19122675, PubMed:21900483, PubMed:22345509, PubMed:28407487). Binds to the promoter of the defense-related gene EDS1 and represses its expression (PubMed:19122675). Binds to the promoter of the defense-related gene NDR1 and represses its expression (PubMed:22345509). Involved in defense against insects (PubMed:23072934, PubMed:22371088). Required for tolerance to the generalist herbivore Trichoplusia ni, and contributes to the positive regulation of genes associated with glucosinolate metabolism (PubMed:23072934). Required for tolerance to Bradysia impatiens larvae. Mediates herbivore-induced wound response (PubMed:22371088). Required for wound-induced jasmonate accumulation (PubMed:23072934, PubMed:22371088). Involved in the regulation of ethylene-induced senescence by binding to the promoter of the senescence-inducer gene EIN3 and repressing its expression (PubMed:22345509). {ECO:0000269\|PubMed:12218065, ECO:0000269\|PubMed:18298954, ECO:0000269\|PubMed:19122675, ECO:0000269\|PubMed:19270186, ECO:0000269\|PubMed:21900483, ECO:0000269\|PubMed:22345509, ECO:0000269\|PubMed:22371088, ECO:0000269\|PubMed:23072934, ECO:0000269\|PubMed:23581962, ECO:0000269\|PubMed:25039701, ECO:0000269\|PubMed:25157030, ECO:0000269\|PubMed:28351986, ECO:0000269\|PubMed:28407487, ECO:0000305\|PubMed:11925432}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00042	PBM	Transfer from AT2G22300	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	KFK32837.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By heat shock, UVB, salt, wounding, ethylene and methyl jasmonate (PubMed:11162426, PubMed:12218065). Induced by infection with the fungal pathogen Golovinomyces cichoracearum (powdery mildew) and the bacterial pathogen Pseudomonas syringae pv tomato strain DC3000 (PubMed:22345509). {ECO:0000269\|PubMed:11162426, ECO:0000269\|PubMed:12218065, ECO:0000269\|PubMed:22345509}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AF506697	0.0	AF506697.1 Arabidopsis thaliana calmodulin-binding transcription factor SR1 (SR1) mRNA, complete cds.
GenBank	AY510025	0.0	AY510025.1 Arabidopsis thaliana ethylene-induced calmodulin-binding protein 1 mRNA, complete cds.
GenBank	BT002459	0.0	BT002459.1 Arabidopsis thaliana Unknown protein mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_024014331.1	0.0	calmodulin-binding transcription activator 3 isoform X2
Swissprot	Q8GSA7	0.0	CMTA3_ARATH; Calmodulin-binding transcription activator 3
TrEMBL	A0A087GSI5	0.0	A0A087GSI5_ARAAL; Uncharacterized protein
STRING	A0A087GSI5	0.0	(Arabis alpina)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM8601	25	35

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G22300.2	0.0	signal responsive 1

Publications ? help Back to Top
Zhang L,Du L,Shen C,Yang Y,Poovaiah BW Regulation of plant immunity through ubiquitin-mediated modulation of Ca(2+) -calmodulin-AtSR1/CAMTA3 signaling. Plant J., 2014. 78(2): p. 269-81 [PMID:24528504] Benn G, et al. A key general stress response motif is regulated non-uniformly by CAMTA transcription factors. Plant J., 2014. 80(1): p. 82-92 [PMID:25039701] Rahman H,Yang J,Xu YP,Munyampundu JP,Cai XZ Phylogeny of Plant CAMTAs and Role of AtCAMTAs in Nonhost Resistance to Xanthomonas oryzae pv. oryzae. Front Plant Sci, 2016. 7: p. 177 [PMID:26973658] Benn G, et al. Plastidial metabolite MEcPP induces a transcriptionally centered stress-response hub via the transcription factor CAMTA3. Proc. Natl. Acad. Sci. U.S.A., 2016. 113(31): p. 8855-60 [PMID:27432993] Kidokoro S, et al. Different Cold-Signaling Pathways Function in the Responses to Rapid and Gradual Decreases in Temperature. Plant Cell, 2017. 29(4): p. 760-774 [PMID:28351986] Lolle S, et al. Matching NLR Immune Receptors to Autoimmunity in camta3 Mutants Using Antimorphic NLR Alleles. Cell Host Microbe, 2017. 21(4): p. 518-529.e4 [PMID:28407487] Kim YS, et al. CAMTA-Mediated Regulation of Salicylic Acid Immunity Pathway Genes in Arabidopsis Exposed to Low Temperature and Pathogen Infection. Plant Cell, 2017. 29(10): p. 2465-2477 [PMID:28982964] Jacob F, et al. A dominant-interfering camta3 mutation compromises primary transcriptional outputs mediated by both cell surface and intracellular immune receptors in Arabidopsis thaliana. New Phytol., 2018. 217(4): p. 1667-1680 [PMID:29226970]