PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_016482517.1
Organism
Nicotiana tabacum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana
Family AP2
Protein Properties Length: 474aa    MW: 52815.3 Da    PI: 6.41
Description AP2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_016482517.1genomeNCBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP254.33.3e-17147196155
             AP2   1 sgykGVrwdkkrgrWvAeIrdpsengkr.krfslgkfgtaeeAakaaiaarkkleg 55 
                     s+y+GV++++++grW+++I+d      + k+++lg f+ta  Aa+a+++a+ k++g
  XP_016482517.1 147 SQYRGVTFYRRTGRWESHIWD------CgKQVYLGGFDTAHAAARAYDRAAIKFRG 196
                     78*******************......55************************998 PP
2AP239.71.2e-12239287153
             AP2   1 sgykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkl 53 
                     s+y+GV+ +k  grW+A+   +     +k+++lg f+++ eAa+a+++a  k 
  XP_016482517.1 239 SKYRGVTLHK-CGRWEARMGQF--L-GKKYIYLGLFDSEIEAARAYDKAVIKC 287
                     89********.7******5553..2.26**********99********98775 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF541719.15E-16147205IPR016177DNA-binding domain
CDDcd000188.19E-12147206No hitNo description
PfamPF008472.2E-9147196IPR001471AP2/ERF domain
SMARTSM003801.3E-30148210IPR001471AP2/ERF domain
Gene3DG3DSA:3.30.730.108.0E-17148204IPR001471AP2/ERF domain
PROSITE profilePS5103217.82148204IPR001471AP2/ERF domain
CDDcd000182.70E-23239299No hitNo description
PfamPF008475.3E-8239286IPR001471AP2/ERF domain
SuperFamilySSF541712.22E-16239299IPR016177DNA-binding domain
SMARTSM003807.1E-30240303IPR001471AP2/ERF domain
Gene3DG3DSA:3.30.730.102.8E-15240298IPR001471AP2/ERF domain
PROSITE profilePS5103215.079240297IPR001471AP2/ERF domain
PRINTSPR003675.3E-5241252IPR001471AP2/ERF domain
PRINTSPR003675.3E-5279299IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 474 aa     Download sequence    Send to blast
MFDLNLGFEE FAMDDDTVHL SYETTTSEKL QELQMENSGT SNSSIVNIET SSTAGDDEFF  60
SCSDDRRRND GYAFDILKGN DYEESEFVTK ELFPLTGGEA ATELLSRQQW LDLSANYGGP  120
AEQRIVVIPQ QRQQVKKSRR GPRSKSSQYR GVTFYRRTGR WESHIWDCGK QVYLGGFDTA  180
HAAARAYDRA AIKFRGLDAD INFNVADYHD DLKQMSNFTK EEFVHILRRQ STGFSRGSSK  240
YRGVTLHKCG RWEARMGQFL GKKYIYLGLF DSEIEAARAY DKAVIKCSGR EAVTNFELST  300
YEGELSAEDN GGASHNLDLN LGIASSSQAD EQHGNTCQMG NTEFLLASNG LTEYRGAMRS  360
PSTTMGSKLP HGRQPLTDRP LLWNGVNTSV FPTFKGTAIG KGMEVDSSPN WTRQDQHPYG  420
GSPSMPLFST AASSGFANST SAAAHQHHFS TGPLPYHHSP SLANMNFAHY YCRS
Functional Description ? help Back to Top
Source Description
UniProtProbable transcription factor (By similarity). Involved in spikelet transition (Probable). Together with IDS1, controls synergistically inflorescence architecture and floral meristem establishment via the regulation of spatio-temporal expression of B- and E-function floral organ identity genes in the lodicules and of spikelet meristem genes (PubMed:22003982). Prevents lemma and palea elongation as well as grain growth (PubMed:28066457). Regulates the transition from spikelet meristem to floral meristem, spikelet meristem determinancy and the floral organ development (PubMed:17144896). {ECO:0000250|UniProtKB:P47927, ECO:0000269|PubMed:17144896, ECO:0000269|PubMed:22003982, ECO:0000269|PubMed:28066457, ECO:0000305|PubMed:26631749}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Target of miR172 microRNA mediated cleavage, particularly during floral organ development. {ECO:0000269|PubMed:20017947, ECO:0000269|PubMed:22003982, ECO:0000305|PubMed:26631749, ECO:0000305|PubMed:28066457}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAF1320020.0AF132002.1 Petunia x hybrida PHAP2B protein (Ap2B) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_016482517.10.0PREDICTED: floral homeotic protein APETALA 2-like isoform X1
SwissprotQ8H4431e-102AP23_ORYSJ; APETALA2-like protein 3
TrEMBLA0A1S4B0R20.0A0A1S4B0R2_TOBAC; floral homeotic protein APETALA 2-like isoform X1
STRINGXP_009606014.10.0(Nicotiana tomentosiformis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA59124116
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G28550.31e-105related to AP2.7
Publications ? help Back to Top
  1. Lee DY,An G
    Two AP2 family genes, supernumerary bract (SNB) and Osindeterminate spikelet 1 (OsIDS1), synergistically control inflorescence architecture and floral meristem establishment in rice.
    Plant J., 2012. 69(3): p. 445-61
    [PMID:22003982]
  2. Wang L, et al.
    Coordinated regulation of vegetative and reproductive branching in rice.
    Proc. Natl. Acad. Sci. U.S.A., 2015. 112(50): p. 15504-9
    [PMID:26631749]
  3. Dai Z,Wang J,Zhu M,Miao X,Shi Z
    OsMADS1 Represses microRNA172 in Elongation of Palea/Lemma Development in Rice.
    Front Plant Sci, 2016. 7: p. 1891
    [PMID:28066457]