PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_010106953.1
Organism
Morus notabilis
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Moraceae; Morus
Family MYB
Protein Properties Length: 333aa    MW: 37420.1 Da    PI: 6.631
Description MYB family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_010106953.1genomeBGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Myb_DNA-binding42.81.2e-131358146
                     TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHH CS
  Myb_DNA-binding  1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqk 46
                     +g+W +eEde l++ v+++G+++W++I ++  + Rt+k+c++rw +
   XP_010106953.1 13 KGPWKAEEDEVLINHVNKYGPRDWSSIRSKGLLQRTGKSCRLRWVN 58
                     79*************************8887799**********87 PP
2Myb_DNA-binding414.4e-1369108344
                      SS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHH CS
  Myb_DNA-binding   3 rWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrw 44 
                      +++ eE+   +++ ++lG++ W++Ia +++ gRt++++k++w
   XP_010106953.1  69 KFSLEEERVVIELQAELGNK-WARIATYLP-GRTDNDVKNFW 108
                      799*****************.*********.*********** PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5129414.284860IPR017930Myb domain
Gene3DG3DSA:1.10.10.601.3E-201161IPR009057Homeodomain-like
SMARTSM007176.7E-111262IPR001005SANT/Myb domain
SuperFamilySSF466897.81E-2812108IPR009057Homeodomain-like
PfamPF002491.1E-111358IPR001005SANT/Myb domain
CDDcd001671.25E-111560No hitNo description
PROSITE profilePS5129419.55961116IPR017930Myb domain
Gene3DG3DSA:1.10.10.602.0E-1762114IPR009057Homeodomain-like
SMARTSM007171.6E-1166114IPR001005SANT/Myb domain
PfamPF002491.0E-1169108IPR001005SANT/Myb domain
CDDcd001675.74E-1069108No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0048235Biological Processpollen sperm cell differentiation
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 333 aa     Download sequence    Send to blast
MELGKKEEGI IRKGPWKAEE DEVLINHVNK YGPRDWSSIR SKGLLQRTGK SCRLRWVNKL  60
RPNLKNGCKF SLEEERVVIE LQAELGNKWA RIATYLPGRT DNDVKNFWSS RQKRLARILH  120
SSSSSSTPNS TINKSHSHNN NNNNNNKHKR PIPIAAHNEV PPLPMDQGRI FSASSAGELS  180
SKVPSYTSSF NENSSEIKMV SLPDLVNPKL LNFEQDLGQP LFNCSTEKNP CIDTQPLNLN  240
PFPPMSQSQL ELAFPSEEHQ DFLARFGEPY FDVFGSLEAS KLGNGTEIPF CIPPFLEPVG  300
KPDNLSPTPD SLFDDFPVDM FDQIESLPSP PPP
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1h8a_C9e-281311427126MYB TRANSFORMING PROTEIN
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that acts as a positive regulator of male germline development by promoting both gametic cell specification and cell cycle progression (PubMed:15694308, PubMed:15618418, PubMed:19300502, PubMed:21285328). Binds to canonical MYB sites 5'-AACCGTC-3', 5'-AAACCGC-3' and 5'-AACCGT-3' in promoters to trigger the expression of male germline-specific or enriched genes (e.g. MGH3, GEX2 and GCS1), including those required for fertilization (PubMed:21285328, PubMed:19300502). Required for sperm cell specification leading to pollen maturation by activating a germline-specific regulon (PubMed:21285328, PubMed:15694308, PubMed:15618418, PubMed:19300502). Involved in pollen mitosis entry at G2-M transition via the regulation of CYCB1-1, DAZ1 and DAZ2 expression (PubMed:15618418, PubMed:19300502, PubMed:24876252). {ECO:0000269|PubMed:15618418, ECO:0000269|PubMed:15694308, ECO:0000269|PubMed:19300502, ECO:0000269|PubMed:21285328, ECO:0000269|PubMed:24876252}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapXP_010106953.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Repressed by the microRNA 159 (miR159); the production of miR159 is stimulated by the anaphase promoting complex/cyclosome (APC/C) (PubMed:21441434). Activated by ARID1 in male germline cells via specific histone acetylation regulation (e.g. H3K9Ac) (PubMed:25057814). {ECO:0000269|PubMed:21441434, ECO:0000269|PubMed:25057814}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_024028365.10.0transcription factor DUO1
SwissprotA0A178VEK79e-82DUO1_ARATH; Transcription factor DUO1
TrEMBLW9RVN70.0W9RVN7_9ROSA; Transcription factor GAMYB
STRINGXP_010106953.10.0(Morus notabilis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF36933164
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G60460.11e-80MYB family protein
Publications ? help Back to Top
  1. Zheng B,He H,Zheng Y,Wu W,McCormick S
    An ARID domain-containing protein within nuclear bodies is required for sperm cell formation in Arabidopsis thaliana.
    PLoS Genet., 2014. 10(7): p. e1004421
    [PMID:25057814]
  2. Peters B, et al.
    A Conserved cis-Regulatory Module Determines Germline Fate through Activation of the Transcription Factor DUO1 Promoter.
    Plant Physiol., 2017. 173(1): p. 280-293
    [PMID:27624837]
  3. Zheng Z, et al.
    Target RNA Secondary Structure Is a Major Determinant of miR159 Efficacy.
    Plant Physiol., 2017. 174(3): p. 1764-1778
    [PMID:28515145]