PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Spipo1G0063200

Organism

Spirodela polyrhiza

Taxonomic ID

29656

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Alismatales; Araceae; Lemnoideae; Spirodela

Family

E2F/DP

Protein Properties

Length: 369aa MW: 40965 Da PI: 4.6979

Description

E2F/DP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Spipo1G0063200	genome	MIPS/IBIS	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	E2F_TDP	77.4	1.4e-24	83	142	7	71
E2F_TDP 7 rlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 +llt+kf++ll+++e+g+++ln++a+ L +v ++RRiYDi+NVLe+++liekk kn+irwkg Spipo1G0063200 83 GLLTKKFISLLQQAEDGTLDLNKAADIL---EV--QKRRIYDITNVLEGVGLIEKKLKNRIRWKG 142 589***********************...99..**************************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM01372	8.2E-28	83	142	IPR003316	E2F/DP family, winged-helix DNA-binding domain
Gene3D	G3DSA:1.10.10.10	2.5E-25	83	144	IPR011991	Winged helix-turn-helix DNA-binding domain
SuperFamily	SSF46785	3.15E-15	83	143	IPR011991	Winged helix-turn-helix DNA-binding domain
Pfam	PF02319	1.7E-22	83	142	IPR003316	E2F/DP family, winged-helix DNA-binding domain
CDD	cd14660	2.98E-43	153	258	No hit	No description
SuperFamily	SSF144074	5.75E-29	154	258	No hit	No description
Pfam	PF16421	9.5E-29	158	257	IPR032198	E2F transcription factor, CC-MB domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005667	Cellular Component	transcription factor complex
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 369 aa Download sequence Send to blast
MACIIGILWI WSYTYGSCKQ SSLLFGDILY FVKLSQNMRL EQRTKKLVVV KGRLILGKKK 60 HLAFMYLQLH LMQMLCIPLV VAGLLTKKFI SLLQQAEDGT LDLNKAADIL EVQKRRIYDI 120 TNVLEGVGLI EKKLKNRIRW KGLDMPRPKE LEDQIGALKA HVENLSSEES SIDGMIRETL 180 ENLRFLSEDE NNKKWLYVTR DDINSLPCFA NDTLVAIKAP HGTSLEVPDP DEGIDFPNKR 240 YQIFLRSSVG PIDCYLISSV DSNPDAGLEA ATTSHDPRLA PMEGVSVEEG DARGDEGPPL 300 VPAECAASDA DGNEAGHTAY SDAPCSQELF SGIMKIVPSE LDSNADYWLL SDLGASITDM 360 WTDCILRV*

Sequence ? help Back to Top

Protein Sequence Length: 369 aa Download sequence Send to blast

MACIIGILWI WSYTYGSCKQ SSLLFGDILY FVKLSQNMRL EQRTKKLVVV KGRLILGKKK  60
HLAFMYLQLH LMQMLCIPLV VAGLLTKKFI SLLQQAEDGT LDLNKAADIL EVQKRRIYDI  120
TNVLEGVGLI EKKLKNRIRW KGLDMPRPKE LEDQIGALKA HVENLSSEES SIDGMIRETL  180
ENLRFLSEDE NNKKWLYVTR DDINSLPCFA NDTLVAIKAP HGTSLEVPDP DEGIDFPNKR  240
YQIFLRSSVG PIDCYLISSV DSNPDAGLEA ATTSHDPRLA PMEGVSVEEG DARGDEGPPL  300
VPAECAASDA DGNEAGHTAY SDAPCSQELF SGIMKIVPSE LDSNADYWLL SDLGASITDM  360
WTDCILRV*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1cf7_A	3e-22	83	143	13	74	PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Involved in the control of cell-cycle progression from G1 to S phase and from G2 to M phase. Stimulates cell proliferation and delays differentiation. Represses cell enlargement and endoreduplication in auxin-free conditions. {ECO:0000269\|PubMed:11669580, ECO:0000269\|PubMed:11786543, ECO:0000269\|PubMed:11862494, ECO:0000269\|PubMed:11891240, ECO:0000269\|PubMed:12913157, ECO:0000269\|PubMed:16055635, ECO:0000269\|PubMed:16514015}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Up-regulated by light and by auxin. May be up-regulated by E2FA. {ECO:0000269\|PubMed:16055635, ECO:0000269\|PubMed:16514015, ECO:0000269\|PubMed:18424613}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_026665351.1	1e-109	transcription factor E2FB-like isoform X1
Swissprot	Q9FV71	2e-87	E2FB_ARATH; Transcription factor E2FB
TrEMBL	A0A1D1YQF1	1e-124	A0A1D1YQF1_9ARAE; Transcription factor E2FB (Fragment)
STRING	XP_008807578.1	1e-108	(Phoenix dactylifera)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Monocots	OGMP625	37	148

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G22220.3	8e-90	E2F transcription factor 1

Link Out ? help Back to Top
Phytozome	Spipo1G0063200

Publications ? help Back to Top
Heyndrickx KS,Vandepoele K Systematic identification of functional plant modules through the integration of complementary data sources. Plant Physiol., 2012. 159(3): p. 884-901 [PMID:22589469] Wu M,Liu L,Hijazi H,Chan C A multi-layer inference approach to reconstruct condition-specific genes and their regulation. Bioinformatics, 2013. 29(12): p. 1541-52 [PMID:23610368] Kobayashi K, et al. Transcriptional repression by MYB3R proteins regulates plant organ growth. EMBO J., 2015. 34(15): p. 1992-2007 [PMID:26069325]