PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Sopen04g025150.1

Organism

Solanum pennellii

Taxonomic ID

28526

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum; Lycopersicon

Family

CAMTA

Protein Properties

Length: 1098aa MW: 122826 Da PI: 5.5959

Description

CAMTA family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Sopen04g025150.1	genome	spenn	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	CG-1	181.3	1.2e-56	20	136	2	118
CG-1 2 lkekkrwlkneeiaaiLenfekheltlelktrpksgsliLynrkkvryfrkDGyswkkkkdgktvrEdhekLKvggvevlycyYahseenptf 94 l+ ++rwl++ ei++iL+n++k++++ e+++rp+sgsl+L++rk++ryfrkDG+sw+kk+dgktv+E+he+LK g+++vl+cyYah+een++f Sopen04g025150.1 20 LEAQHRWLRPAEICEILKNYQKFRIAPEPPNRPPSGSLFLFDRKVLRYFRKDGHSWRKKRDGKTVKEAHERLKAGSIDVLHCYYAHGEENENF 112 5679*************************************************************************************** PP CG-1 95 qrrcywlLeeelekivlvhylevk 118 qrr+yw+Leee+++ivlvhy+evk Sopen04g025150.1 113 QRRSYWMLEEEMSHIVLVHYREVK 136 *******************986 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51437	82.727	15	141	IPR005559	CG-1 DNA-binding domain
SMART	SM01076	3.8E-79	18	136	IPR005559	CG-1 DNA-binding domain
Pfam	PF03859	1.0E-49	21	134	IPR005559	CG-1 DNA-binding domain
Gene3D	G3DSA:2.60.40.10	3.2E-4	513	598	IPR013783	Immunoglobulin-like fold
Pfam	PF01833	9.8E-5	514	592	IPR002909	IPT domain
SuperFamily	SSF81296	6.3E-16	514	600	IPR014756	Immunoglobulin E-set
Gene3D	G3DSA:1.25.40.20	2.6E-19	698	813	IPR020683	Ankyrin repeat-containing domain
CDD	cd00204	4.46E-14	700	808	No hit	No description
PROSITE profile	PS50297	19.439	700	821	IPR020683	Ankyrin repeat-containing domain
SuperFamily	SSF48403	7.46E-19	705	811	IPR020683	Ankyrin repeat-containing domain
Pfam	PF12796	5.7E-9	722	812	IPR020683	Ankyrin repeat-containing domain
PROSITE profile	PS50088	10.259	750	782	IPR002110	Ankyrin repeat
SMART	SM00248	0.011	750	779	IPR002110	Ankyrin repeat
SMART	SM00248	120	789	818	IPR002110	Ankyrin repeat
SuperFamily	SSF52540	3.72E-6	921	974	IPR027417	P-loop containing nucleoside triphosphate hydrolase
SMART	SM00015	48	923	945	IPR000048	IQ motif, EF-hand binding site
PROSITE profile	PS50096	7.126	925	953	IPR000048	IQ motif, EF-hand binding site
Pfam	PF00612	0.11	925	944	IPR000048	IQ motif, EF-hand binding site
SMART	SM00015	0.0042	946	968	IPR000048	IQ motif, EF-hand binding site
PROSITE profile	PS50096	9.285	947	971	IPR000048	IQ motif, EF-hand binding site
Pfam	PF00612	5.0E-4	949	968	IPR000048	IQ motif, EF-hand binding site

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009409	Biological Process	response to cold
GO:0010150	Biological Process	leaf senescence
GO:0042742	Biological Process	defense response to bacterium
GO:0050832	Biological Process	defense response to fungus
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0005516	Molecular Function	calmodulin binding

Sequence ? help Back to Top
Protein Sequence Length: 1098 aa Download sequence Send to blast
MADSRRYGLN AQLDIEQILL EAQHRWLRPA EICEILKNYQ KFRIAPEPPN RPPSGSLFLF 60 DRKVLRYFRK DGHSWRKKRD GKTVKEAHER LKAGSIDVLH CYYAHGEENE NFQRRSYWML 120 EEEMSHIVLV HYREVKGNRT NFSRIREPLQ VTPDLQETDE DVHSSEVDSS ASTKFYPNDY 180 QVNSQVTDTT SFSSAQASEY EDAESVYNQH PTSGFHSFLD AQPSAGDGLA VPYHPIPFSN 240 DQVQFAGSSG TSFSSIPPGN GNTNTANTYV PSRNLDFASW GTISVNNPAA YQSLHFQPSA 300 QSSANNMMHE QGNTTMGQLF SNDFTRQEHE NHIDGLGNWQ TSEVDSSFIS KWSMDQKLNP 360 DLTSGQTIGS SGVYGVERHN SLEASQLLSA QQDKHPMQNE LQSQLSDANI GGSLNADLDH 420 NLSLGVKTDY SALKQPLLDG VLKREGLKKL DSFDRWISKE LGDVSESHMQ SNSSSYWDNV 480 GDEDGVDNST IASQVQLDTY VLSPSLAQDQ IFSIIDFSPN WAFSGSEIKV LITGRFLKSQ 540 QEVENCSWAC MFGELEVPAE VIADGVLRCH TPVQKAGRVP FYITCSNRLA CSEVREFEFR 600 VTEGQDVDVA NPNSCSSSES LLHMRFGKLL SLESFVSQTS PPISEDDVSH ISSKINSLLR 660 DDDNEWEEML HLTSENNFMA EKVKDQLLQK LLKEKLRVWL LQKVAEGGKG PNILDEGGQG 720 VLHFAAALGY DWAVPPTIAA GVSVNFRDVN GWTALHWAAS YGRERTVGFL ISLGAAAGAL 780 TDPTPKHPSG RTPADLASSN GHKGIAGYLA ESSLSSHLSS LELKEKKQGE NEQAFGEAVQ 840 TVSERTATPA WDGDWSHGVS LKDSLAAVRN ATQAAARIHQ VFRVQSFQRK QLKEYGGSEF 900 GLSDERALSL LAMKTNRAGQ HDEPHAAAVR IQNKFRSWKG RRDFLLIRQR IIKIQAHVRG 960 HQVRNKYKNI IWSVGILEKV ILRWRRKGSG LRGFKPEAPT EGSNMQDQPV QEDDYDFLKE 1020 GRKQTEERLQ KALERVKSMV QYPEARDQYR RLLNVVSDMQ EPNSTAASYN SAEAVDFNDD 1080 LIDLGDLLDD DTFMPTAP

Sequence ? help Back to Top

Protein Sequence Length: 1098 aa Download sequence Send to blast

MADSRRYGLN AQLDIEQILL EAQHRWLRPA EICEILKNYQ KFRIAPEPPN RPPSGSLFLF  60
DRKVLRYFRK DGHSWRKKRD GKTVKEAHER LKAGSIDVLH CYYAHGEENE NFQRRSYWML  120
EEEMSHIVLV HYREVKGNRT NFSRIREPLQ VTPDLQETDE DVHSSEVDSS ASTKFYPNDY  180
QVNSQVTDTT SFSSAQASEY EDAESVYNQH PTSGFHSFLD AQPSAGDGLA VPYHPIPFSN  240
DQVQFAGSSG TSFSSIPPGN GNTNTANTYV PSRNLDFASW GTISVNNPAA YQSLHFQPSA  300
QSSANNMMHE QGNTTMGQLF SNDFTRQEHE NHIDGLGNWQ TSEVDSSFIS KWSMDQKLNP  360
DLTSGQTIGS SGVYGVERHN SLEASQLLSA QQDKHPMQNE LQSQLSDANI GGSLNADLDH  420
NLSLGVKTDY SALKQPLLDG VLKREGLKKL DSFDRWISKE LGDVSESHMQ SNSSSYWDNV  480
GDEDGVDNST IASQVQLDTY VLSPSLAQDQ IFSIIDFSPN WAFSGSEIKV LITGRFLKSQ  540
QEVENCSWAC MFGELEVPAE VIADGVLRCH TPVQKAGRVP FYITCSNRLA CSEVREFEFR  600
VTEGQDVDVA NPNSCSSSES LLHMRFGKLL SLESFVSQTS PPISEDDVSH ISSKINSLLR  660
DDDNEWEEML HLTSENNFMA EKVKDQLLQK LLKEKLRVWL LQKVAEGGKG PNILDEGGQG  720
VLHFAAALGY DWAVPPTIAA GVSVNFRDVN GWTALHWAAS YGRERTVGFL ISLGAAAGAL  780
TDPTPKHPSG RTPADLASSN GHKGIAGYLA ESSLSSHLSS LELKEKKQGE NEQAFGEAVQ  840
TVSERTATPA WDGDWSHGVS LKDSLAAVRN ATQAAARIHQ VFRVQSFQRK QLKEYGGSEF  900
GLSDERALSL LAMKTNRAGQ HDEPHAAAVR IQNKFRSWKG RRDFLLIRQR IIKIQAHVRG  960
HQVRNKYKNI IWSVGILEKV ILRWRRKGSG LRGFKPEAPT EGSNMQDQPV QEDDYDFLKE  1020
GRKQTEERLQ KALERVKSMV QYPEARDQYR RLLNVVSDMQ EPNSTAASYN SAEAVDFNDD  1080
LIDLGDLLDD DTFMPTAP

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
4hb5_A	4e-12	701	809	20	122	Engineered Protein
4hb5_B	4e-12	701	809	20	122	Engineered Protein
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds to the DNA consensus sequence 5'-[ACG]CGCG[GTC]-3'. Binds calmodulin in a calcium-dependent manner in vitro (PubMed:12218065). Regulates transcriptional activity in response to calcium signals (Probable). Involved in freezing tolerance in association with CAMTA1 and CAMTA2 (PubMed:23581962). Required for the cold-induced expression of DREB1B/CBF1, DREB1C/CBF2, ZAT12 and GOLS3 (PubMed:19270186). Involved in response to cold. Contributes together with CAMTA5 to the positive regulation of the cold-induced expression of DREB1A/CBF3, DREB1B/CBF1 and DREB1C/CBF2 (PubMed:28351986). Involved together with CAMTA2 and CAMTA4 in the positive regulation of a general stress response (GSR) (PubMed:25039701). Involved in the regulation of GSR amplitude downstream of MEKK1 (PubMed:25157030). Involved in the regulation of a set of genes involved in defense responses against pathogens (PubMed:18298954). Involved in the regulation of both basal resistance and systemic acquired resistance (SAR) (PubMed:21900483). Acts as negative regulator of plant immunity (PubMed:19122675, PubMed:21900483, PubMed:22345509, PubMed:28407487). Binds to the promoter of the defense-related gene EDS1 and represses its expression (PubMed:19122675). Binds to the promoter of the defense-related gene NDR1 and represses its expression (PubMed:22345509). Involved in defense against insects (PubMed:23072934, PubMed:22371088). Required for tolerance to the generalist herbivore Trichoplusia ni, and contributes to the positive regulation of genes associated with glucosinolate metabolism (PubMed:23072934). Required for tolerance to Bradysia impatiens larvae. Mediates herbivore-induced wound response (PubMed:22371088). Required for wound-induced jasmonate accumulation (PubMed:23072934, PubMed:22371088). Involved in the regulation of ethylene-induced senescence by binding to the promoter of the senescence-inducer gene EIN3 and repressing its expression (PubMed:22345509). {ECO:0000269\|PubMed:12218065, ECO:0000269\|PubMed:18298954, ECO:0000269\|PubMed:19122675, ECO:0000269\|PubMed:19270186, ECO:0000269\|PubMed:21900483, ECO:0000269\|PubMed:22345509, ECO:0000269\|PubMed:22371088, ECO:0000269\|PubMed:23072934, ECO:0000269\|PubMed:23581962, ECO:0000269\|PubMed:25039701, ECO:0000269\|PubMed:25157030, ECO:0000269\|PubMed:28351986, ECO:0000269\|PubMed:28407487, ECO:0000305\|PubMed:11925432}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00042	PBM	Transfer from AT2G22300	Download

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By heat shock, UVB, salt, wounding, ethylene and methyl jasmonate (PubMed:11162426, PubMed:12218065). Induced by infection with the fungal pathogen Golovinomyces cichoracearum (powdery mildew) and the bacterial pathogen Pseudomonas syringae pv tomato strain DC3000 (PubMed:22345509). {ECO:0000269\|PubMed:11162426, ECO:0000269\|PubMed:12218065, ECO:0000269\|PubMed:22345509}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	GU170838	0.0	GU170838.1 Solanum lycopersicum cultivar Rutgers calmodulin-binding protein mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_015073473.1	0.0	calmodulin-binding transcription activator 3-like isoform X1
Swissprot	Q8GSA7	0.0	CMTA3_ARATH; Calmodulin-binding transcription activator 3
TrEMBL	A0A3Q7G683	0.0	A0A3Q7G683_SOLLC; Uncharacterized protein
STRING	XP_009613615.1	0.0	(Nicotiana tomentosiformis)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA2230	21	46

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G22300.2	0.0	signal responsive 1

Publications ? help Back to Top
Zhang L,Du L,Shen C,Yang Y,Poovaiah BW Regulation of plant immunity through ubiquitin-mediated modulation of Ca(2+) -calmodulin-AtSR1/CAMTA3 signaling. Plant J., 2014. 78(2): p. 269-81 [PMID:24528504] Benn G, et al. A key general stress response motif is regulated non-uniformly by CAMTA transcription factors. Plant J., 2014. 80(1): p. 82-92 [PMID:25039701] Rahman H,Yang J,Xu YP,Munyampundu JP,Cai XZ Phylogeny of Plant CAMTAs and Role of AtCAMTAs in Nonhost Resistance to Xanthomonas oryzae pv. oryzae. Front Plant Sci, 2016. 7: p. 177 [PMID:26973658] Benn G, et al. Plastidial metabolite MEcPP induces a transcriptionally centered stress-response hub via the transcription factor CAMTA3. Proc. Natl. Acad. Sci. U.S.A., 2016. 113(31): p. 8855-60 [PMID:27432993] Kidokoro S, et al. Different Cold-Signaling Pathways Function in the Responses to Rapid and Gradual Decreases in Temperature. Plant Cell, 2017. 29(4): p. 760-774 [PMID:28351986] Lolle S, et al. Matching NLR Immune Receptors to Autoimmunity in camta3 Mutants Using Antimorphic NLR Alleles. Cell Host Microbe, 2017. 21(4): p. 518-529.e4 [PMID:28407487] Kim YS, et al. CAMTA-Mediated Regulation of Salicylic Acid Immunity Pathway Genes in Arabidopsis Exposed to Low Temperature and Pathogen Infection. Plant Cell, 2017. 29(10): p. 2465-2477 [PMID:28982964] Jacob F, et al. A dominant-interfering camta3 mutation compromises primary transcriptional outputs mediated by both cell surface and intracellular immune receptors in Arabidopsis thaliana. New Phytol., 2018. 217(4): p. 1667-1680 [PMID:29226970]