PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Neem_1618_f_8
Organism
Azadirachta indica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Meliaceae; Azadirachta
Family bHLH
Protein Properties Length: 96aa    MW: 10868.1 Da    PI: 6.5964
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Neem_1618_f_8genomeNGDView Nucleic Acid
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH26.31.4e-0819591555
                   HHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS
            HLH 15 riNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55
                   +iN  + +L+ llP++ + +++ +s +e+L+++++YI+ Lq
  Neem_1618_f_8 19 EINRLILKLQPLLPQLNQRQDGTVSVSEVLKETCNYIRRLQ 59
                   7**************879**********************9 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5088810.004458IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.106.4E-81875IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamilySSF474599.68E-91876IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000107.6E-61959IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 96 aa     Download sequence    Send to blast
MSSRRSSSSS RASKMTEEEI NRLILKLQPL LPQLNQRQDG TVSVSEVLKE TCNYIRRLQS  60
EADDLSERLS QLLDSMDSSS NSSGVDISLR NYCNNR
Functional Description ? help Back to Top
Source Description
UniProtAtypical and probable non DNA-binding bHLH transcription factor that integrates multiple signaling pathways to regulate cell elongation and plant development. Regulates light responses by binding and inhibiting the activity of the bHLH transcription factor HFR1, a critical regulator of light signaling and shade avoidance. May have a regulatory role in various aspects of gibberellin-dependent growth and development. {ECO:0000269|PubMed:16527868, ECO:0000269|PubMed:20305124}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Not induced by exogenous gibberellin. {ECO:0000269|PubMed:16527868}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_021651758.12e-30transcription factor PRE3-like
SwissprotF4JCN96e-22PRE4_ARATH; Transcription factor PRE4
TrEMBLV4THM78e-29V4THM7_9ROSI; Uncharacterized protein (Fragment)
STRINGXP_006439622.11e-29(Citrus clementina)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM25928225
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G15160.16e-09BANQUO 2
Publications ? help Back to Top
  1. Ezer D, et al.
    The G-Box Transcriptional Regulatory Code in Arabidopsis.
    Plant Physiol., 2017. 175(2): p. 628-640
    [PMID:28864470]