PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Home  TFext  BLAST  Prediction  Download  Help  About  Links  PlantRegMap
(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT5G15160.1
Common NameBHLH134, BNQ2, F8M21.50, PRE2
Organism
Arabidopsis thaliana
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family bHLH
Protein Properties Length: 94aa    MW: 10545.7 Da    PI: 10.1071
Description BANQUO 2
Gene Model
Gene Model ID Type Source Coding Sequence
AT5G15160.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH22.91.6e-0719601454
                 HHHHHHHHHHHCTSCC.C...TTS-STCHHHHHHHHHHHHHH CS
          HLH 14 driNsafeeLrellPk.askapskKlsKaeiLekAveYIksL 54
                 d+i + +++Lr+ +P+ + + +s  +s + +L+++++YI++L
  AT5G15160.1 19 DQITDLISKLRQSIPEiRQNRRSNTVSASKVLQETCNYIRNL 60
                 799*************9977777779999***********98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5088810.252560IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamilySSF474597.85E-81884IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000108.7E-51960IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.108.0E-81963IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009640Biological Processphotomorphogenesis
GO:0009740Biological Processgibberellic acid mediated signaling pathway
GO:0040008Biological Processregulation of growth
GO:0048510Biological Processregulation of timing of transition from vegetative to reproductive phase
GO:0005634Cellular Componentnucleus
GO:0005773Cellular Componentvacuole
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0005515Molecular Functionprotein binding
GO:0046983Molecular Functionprotein dimerization activity
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000005anatomycultured plant cell
PO:0000013anatomycauline leaf
PO:0000037anatomyshoot apex
PO:0000230anatomyinflorescence meristem
PO:0000293anatomyguard cell
PO:0004703anatomycarpel primordium
PO:0004705anatomystamen primordium
PO:0008019anatomyleaf lamina base
PO:0009009anatomyplant embryo
PO:0009010anatomyseed
PO:0009025anatomyvascular leaf
PO:0009029anatomystamen
PO:0009030anatomycarpel
PO:0009031anatomysepal
PO:0009032anatomypetal
PO:0009046anatomyflower
PO:0009047anatomystem
PO:0009052anatomyflower pedicel
PO:0020038anatomypetiole
PO:0020100anatomyhypocotyl
PO:0020137anatomyleaf apex
PO:0025022anatomycollective leaf structure
PO:0001054developmental stagevascular leaf senescent stage
PO:0001078developmental stageplant embryo cotyledonary stage
PO:0001081developmental stagemature plant embryo stage
PO:0001185developmental stageplant embryo globular stage
PO:0004507developmental stageplant embryo bilateral stage
PO:0007064developmental stageLP.12 twelve leaves visible stage
PO:0007098developmental stageLP.02 two leaves visible stage
PO:0007103developmental stageLP.10 ten leaves visible stage
PO:0007115developmental stageLP.04 four leaves visible stage
PO:0007123developmental stageLP.06 six leaves visible stage
PO:0007611developmental stagepetal differentiation and expansion stage
PO:0007616developmental stageflowering stage
Sequence ? help Back to Top
Protein Sequence    Length: 94 aa     Download sequence    Send to blast
MSSSRRSRQA SSSSRISDDQ ITDLISKLRQ SIPEIRQNRR SNTVSASKVL QETCNYIRNL  60
NKEADDLSDR LTQLLESIDP NSPQAAVIRS LING
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
At.17632e-84leaf
Expression -- Microarray ? help Back to Top
Source ID E-value
Genevisible250155_at1e-140
Expression AtlasAT5G15160-
AtGenExpressAT5G15160-
ATTED-IIAT5G15160-
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Expressed in roots, leaves, stems and flowers. {ECO:0000269|PubMed:16527868}.
Functional Description ? help Back to Top
Source Description
TAIRBNQ2 belongs to a family of atypical non-DNA binding basic helix-loop-helix (bHLH) proteins that heterodimerize with and negatively regulate bHLH transcription factors. Directly and negatively regulated by AP3 and PI in petals.Required for appropriate regulation of flowering time.
UniProtAtypical and probable non DNA-binding bHLH transcription factor that integrates multiple signaling pathways to regulate cell elongation and plant development. Regulates light responses by binding and inhibiting the activity of the bHLH transcription factor HFR1, a critical regulator of light signaling and shade avoidance. May have a regulatory role in various aspects of gibberellin-dependent growth and development. {ECO:0000269|PubMed:16527868, ECO:0000269|PubMed:20305124}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT5G15160.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Not induced by exogenous gibberellin. {ECO:0000269|PubMed:16527868}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Interaction ? help Back to Top
Source Intact With
IntActSearch Q9LXG5
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT5G15160
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAK1188871e-158AK118887.1 Arabidopsis thaliana At5g15160 mRNA for unknown protein, complete cds, clone: RAFL21-22-D11.
GenBankBT0054601e-158BT005460.1 Arabidopsis thaliana clone U51275 putative bHLH protein (At5g15160) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_197020.14e-59BANQUO 2
RefseqXP_002873710.14e-59transcription factor PRE2
SwissprotQ9LXG54e-60PRE2_ARATH; Transcription factor PRE2
TrEMBLD7M6S09e-58D7M6S0_ARALL; BHLH family protein
STRINGAT5G15160.12e-58(Arabidopsis thaliana)
STRINGscaffold_601543.12e-58(Arabidopsis lyrata)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM25928225
Representative plantOGRP18771240
Publications ? help Back to Top
  1. Seki M, et al.
    Functional annotation of a full-length Arabidopsis cDNA collection.
    Science, 2002. 296(5565): p. 141-5
    [PMID:11910074]
  2. Heim MA, et al.
    The basic helix-loop-helix transcription factor family in plants: a genome-wide study of protein structure and functional diversity.
    Mol. Biol. Evol., 2003. 20(5): p. 735-47
    [PMID:12679534]
  3. Dal Bosco C, et al.
    Inactivation of the chloroplast ATP synthase gamma subunit results in high non-photochemical fluorescence quenching and altered nuclear gene expression in Arabidopsis thaliana.
    J. Biol. Chem., 2004. 279(2): p. 1060-9
    [PMID:14576160]
  4. Yamada K, et al.
    Empirical analysis of transcriptional activity in the Arabidopsis genome.
    Science, 2003. 302(5646): p. 842-6
    [PMID:14593172]
  5. Bailey PC, et al.
    Update on the basic helix-loop-helix transcription factor gene family in Arabidopsis thaliana.
    Plant Cell, 2003. 15(11): p. 2497-502
    [PMID:14600211]
  6. Carter C, et al.
    The vegetative vacuole proteome of Arabidopsis thaliana reveals predicted and unexpected proteins.
    Plant Cell, 2004. 16(12): p. 3285-303
    [PMID:15539469]
  7. Nagata T,Yamada H,Du Z,Todoriki S,Kikuchi S
    Microarray analysis of genes that respond to gamma-irradiation in Arabidopsis.
    J. Agric. Food Chem., 2005. 53(4): p. 1022-30
    [PMID:15713015]
  8. Esmon CA, et al.
    A gradient of auxin and auxin-dependent transcription precedes tropic growth responses.
    Proc. Natl. Acad. Sci. U.S.A., 2006. 103(1): p. 236-41
    [PMID:16371470]
  9. Lee S, et al.
    Overexpression of PRE1 and its homologous genes activates Gibberellin-dependent responses in Arabidopsis thaliana.
    Plant Cell Physiol., 2006. 47(5): p. 591-600
    [PMID:16527868]
  10. Jung S, et al.
    Synteny conservation between the Prunus genome and both the present and ancestral Arabidopsis genomes.
    BMC Genomics, 2006. 7: p. 81
    [PMID:16615871]
  11. Hyun Y,Lee I
    KIDARI, encoding a non-DNA Binding bHLH protein, represses light signal transduction in Arabidopsis thaliana.
    Plant Mol. Biol., 2006. 61(1-2): p. 283-96
    [PMID:16786307]
  12. Nishizawa A, et al.
    Arabidopsis heat shock transcription factor A2 as a key regulator in response to several types of environmental stress.
    Plant J., 2006. 48(4): p. 535-47
    [PMID:17059409]
  13. Che P,Lall S,Howell SH
    Developmental steps in acquiring competence for shoot development in Arabidopsis tissue culture.
    Planta, 2007. 226(5): p. 1183-94
    [PMID:17581762]
  14. Ascencio-Ib
    Global analysis of Arabidopsis gene expression uncovers a complex array of changes impacting pathogen response and cell cycle during geminivirus infection.
    Plant Physiol., 2008. 148(1): p. 436-54
    [PMID:18650403]
  15. Zhang LY, et al.
    Antagonistic HLH/bHLH transcription factors mediate brassinosteroid regulation of cell elongation and plant development in rice and Arabidopsis.
    Plant Cell, 2009. 21(12): p. 3767-80
    [PMID:20009022]
  16. Wang H, et al.
    Regulation of Arabidopsis brassinosteroid signaling by atypical basic helix-loop-helix proteins.
    Plant Cell, 2009. 21(12): p. 3781-91
    [PMID:20023194]
  17. Mara CD,Huang T,Irish VF
    The Arabidopsis floral homeotic proteins APETALA3 and PISTILLATA negatively regulate the BANQUO genes implicated in light signaling.
    Plant Cell, 2010. 22(3): p. 690-702
    [PMID:20305124]
  18. Arabidopsis Interactome Mapping Consortium
    Evidence for network evolution in an Arabidopsis interactome map.
    Science, 2011. 333(6042): p. 601-7
    [PMID:21798944]
  19. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  20. Mao WT, et al.
    The C-Terminal Sequence and PI motif of the Orchid (Oncidium Gower Ramsey) PISTILLATA (PI) Ortholog Determine its Ability to Bind AP3 Orthologs and Enter the Nucleus to Regulate Downstream Genes Controlling Petal and Stamen Formation.
    Plant Cell Physiol., 2015. 56(11): p. 2079-99
    [PMID:26423960]
  21. Ezer D, et al.
    The G-Box Transcriptional Regulatory Code in Arabidopsis.
    Plant Physiol., 2017. 175(2): p. 628-640
    [PMID:28864470]