PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Medtr5g074400.1
Common NameMTR_5g074400
Organism
Medicago truncatula
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Trifolieae; Medicago
Family WRKY
Protein Properties Length: 582aa    MW: 64565.1 Da    PI: 6.9923
Description WRKY family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Medtr5g074400.1genomeMtView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1WRKY103.41.2e-32243300260
                      --SS-EEEEEEE--TT-SS-EEEEEE-STT---EEEEEE-SSSTTEEEEEEES--SS-- CS
             WRKY   2 dDgynWrKYGqKevkgsefprsYYrCtsagCpvkkkversaedpkvveitYegeHnhek 60 
                      dDgynWrKYGqK+vkgse+prsYY+Ct+++Cp+kkkvers  +++v+ei+Y+g+Hnh+k
  Medtr5g074400.1 243 DDGYNWRKYGQKQVKGSENPRSYYKCTYPNCPTKKKVERSI-EGQVTEIVYKGTHNHPK 300
                      8****************************************.***************85 PP
2WRKY106.71.1e-33419477159
                      ---SS-EEEEEEE--TT-SS-EEEEEE-STT---EEEEEE-SSSTTEEEEEEES--SS- CS
             WRKY   1 ldDgynWrKYGqKevkgsefprsYYrCtsagCpvkkkversaedpkvveitYegeHnhe 59 
                      ldDgy+WrKYGqK+vkg+++prsYY+Ct+++Cpv+k+ver+++d ++v++tYeg+Hnh+
  Medtr5g074400.1 419 LDDGYRWRKYGQKVVKGNPNPRSYYKCTHPNCPVRKHVERASHDLRAVITTYEGKHNHD 477
                      59********************************************************7 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:2.20.25.803.8E-27236301IPR003657WRKY domain
SuperFamilySSF1182903.66E-25241301IPR003657WRKY domain
SMARTSM007749.1E-35242300IPR003657WRKY domain
PROSITE profilePS5081123.307243301IPR003657WRKY domain
PfamPF031062.8E-25243299IPR003657WRKY domain
Gene3DG3DSA:2.20.25.801.7E-37404479IPR003657WRKY domain
SuperFamilySSF1182901.23E-29411479IPR003657WRKY domain
PROSITE profilePS5081137.344414479IPR003657WRKY domain
SMARTSM007741.9E-39419478IPR003657WRKY domain
PfamPF031067.5E-26420477IPR003657WRKY domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0009788Biological Processnegative regulation of abscisic acid-activated signaling pathway
GO:0009938Biological Processnegative regulation of gibberellic acid mediated signaling pathway
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 582 aa     Download sequence    Send to blast
MASSSTSSFE NNNNNNNHQN SLNGFNNFTF STHPFMSTTF SDLLASPASA SASDDNNNSR  60
GVPKFKSTPP PSLPLSPPPV SPSSYFSIPP GLSPAEFLDS PVMLNSSNIL PSPTTGAFAA  120
QSNYNWMNNS EGNQQMRKEN FSFQTQQQGP VVSASTTTFQ SSTVGGVQQQ QQWSYIENTN  180
QNAFSSEKNM IQTTENNNSS MQSFSPEIAS VQTNNTNNGF QSDYSNYQQP QQQPTQTLSR  240
RSDDGYNWRK YGQKQVKGSE NPRSYYKCTY PNCPTKKKVE RSIEGQVTEI VYKGTHNHPK  300
PQCTRRNSSS SSNALVVVPV NPINEIHDQS YASHGNGQMD SAATPENSSI SIGGDDDFEQ  360
SSHQRSRSGG AGDEFDEEEP EAKRWKNEGE NEGISAQPAS RTVREPRVVV QTTSDIDILD  420
DGYRWRKYGQ KVVKGNPNPR SYYKCTHPNC PVRKHVERAS HDLRAVITTY EGKHNHDVPA  480
ARGSGSHSVN RPMPNNPSNP NNAAARPLQI QRPQQAPQGQ SPFNLQMLQG QGNYGFSRFE  540
NQMVPYMNQQ QQQQQQMAEN GFSSRAKEEP KDDMFLESLL C*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1wj2_A3e-33243480878Probable WRKY transcription factor 4
2lex_A3e-33243480878Probable WRKY transcription factor 4
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Mtr.141960.0leaf| root
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: In dry seeds, expressed in aleurone cells and embryos. Levels drop rapidly but transiently in the embryos of imbibed seeds. {ECO:0000250|UniProtKB:Q6IEQ7}.
UniprotTISSUE SPECIFICITY: Expressed in aleurone cells. Mostly expressed in aleurone layers and leaves, and, to a lower extent, in roots, panicles and embryos. {ECO:0000250|UniProtKB:Q6IEQ7}.
Functional Description ? help Back to Top
Source Description
UniProtTranscription repressor (By similarity). Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element. Negative regulator of both gibberellic acid (GA) and abscisic acid (ABA) signaling in aleurone cells, probably by interfering with GAM1, via the specific repression of GA- and ABA-induced promoters (By similarity). {ECO:0000250|UniProtKB:Q6IEQ7, ECO:0000250|UniProtKB:Q6QHD1}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapMedtr5g074400.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by abscisic acid (ABA) in aleurone cells, embryos, roots and leaves (PubMed:25110688). Slightly down-regulated by gibberellic acid (GA) (By similarity). Accumulates in response to jasmonic acid (MeJA) (PubMed:16919842). {ECO:0000250|UniProtKB:Q6IEQ7, ECO:0000269|PubMed:16919842, ECO:0000269|PubMed:25110688}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankCR9329600.0CR932960.3 Medicago truncatula chromosome 5 clone mth4-7a5, COMPLETE SEQUENCE.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_003615949.10.0WRKY transcription factor WRKY24 isoform X2
SwissprotQ6B6R41e-131WRK24_ORYSI; WRKY transcription factor WRKY24
TrEMBLG7K5T20.0G7K5T2_MEDTR; WRKY transcription factor
STRINGAES989070.0(Medicago truncatula)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF107734114
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G38470.11e-102WRKY DNA-binding protein 33
Publications ? help Back to Top
  1. Young ND, et al.
    The Medicago genome provides insight into the evolution of rhizobial symbioses.
    Nature, 2011. 480(7378): p. 520-4
    [PMID:22089132]
  2. Basu S,Roychoudhury A
    Expression profiling of abiotic stress-inducible genes in response to multiple stresses in rice (Oryza sativa L.) varieties with contrasting level of stress tolerance.
    Biomed Res Int, 2014. 2014: p. 706890
    [PMID:25110688]