PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Medtr5g073620.1
Common NameMTR_5g073620
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Trifolieae; Medicago
Family WRKY
Protein Properties Length: 1074aa    MW: 123811 Da    PI: 7.2364
Description WRKY family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Medtr5g073620.1genomeMtView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1WRKY64.51.7e-20672732259
                      --SS-EEEEEEE--TT-SS-EEEEEE-ST...T---EEEEEE-SSSTTEEEEEEES--SS- CS
             WRKY   2 dDgynWrKYGqKevkgsefprsYYrCtsa...gCpvkkkversaedpkvveitYegeHnhe 59 
                      +Dg++W KYG Ke+ g  +prsYYrC +     C++kkkv++  + p+++e+ Y+g H+++
  Medtr5g073620.1 672 EDGFTWTKYGMKEIPGFIYPRSYYRCNHVklyACRAKKKVQQLGDHPNIFEVRYNGGHTCR 732
                      7***************************98999**************************96 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF747884.03E-77249594IPR016159Cullin repeat-like-containing domain
PfamPF030819.3E-68358594IPR004140Exocyst complex protein Exo70
Gene3DG3DSA:2.20.25.805.3E-19669732IPR003657WRKY domain
SuperFamilySSF1182901.83E-18670733IPR003657WRKY domain
SMARTSM007741.7E-23671733IPR003657WRKY domain
PROSITE profilePS5081116.26672734IPR003657WRKY domain
PfamPF031064.0E-19672732IPR003657WRKY domain
PfamPF030814.8E-448501063IPR004140Exocyst complex protein Exo70
SuperFamilySSF747881.2E-338541066IPR016159Cullin repeat-like-containing domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0006887Biological Processexocytosis
GO:0000145Cellular Componentexocyst
GO:0016021Cellular Componentintegral component of membrane
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 1074 aa     Download sequence    Send to blast
MVHTLIQTWR WMMLPKVWRF VGFASSLVGL VCYALSSSFN YLFGEWNLLK IFLYSAFSFI  60
ICLVILFAKK LQHSSSLRFK AHSAFLVLTL TSIYSFFFDK VMNGKPDAYS LISCAAFAIM  120
SLSLSRQTQW GFEIDLLYFF LGCLIVQLMK IKLQLLILGA GFSYCLIILR SSFSSLDTGE  180
NSQYSSELQD ENSVILYVDS LQSPGVNNNI SLQSPSVNNN ISSATSSIDS PQLVISTNVG  240
SMMEQLGTYV KALEHENSNL IQVISEHVEK YVEEHSQLVV TDPNLMMDAL KPQTINDLEE  300
IAKVMCMAGF EKDFSDVYNN CRRECLDKCL MHKLFGLQKL SIEDVHNMSS KDLEDKIERW  360
IRTFNVALKV LFPSERRLCD RIFFGFSSAA DFSFMEICRE STIQLLNFFD YVSSGSHSPE  420
RLFKILEVFE TLRDMIPEFA SLFCDQYSMS LRNEATAIWK RLGKTIRDIF KELEYLIGRD  480
LTKVINFGGG LQPITQHVMN YLRVVCRSQQ TLEQVFYDSS LSSKIHRIID TLESNLEAKS  540
KCYVDPSLGY IFLINNHTYI VEMTKDNELG TLLGDYWLQK YTEKVWHYHR QYHKTKGAIA  600
SSVVLDFFRS NYERIRNIKG GEVLEVYQED MKEIEISPLQ PGERRKKLET EITTIVISPE  660
PQFGNTYKMP PEDGFTWTKY GMKEIPGFIY PRSYYRCNHV KLYACRAKKK VQQLGDHPNI  720
FEVRYNGGHT CRMSLTIPSL FVPARQPLDI SIDGIQSTMP TSSTLYSRRI SSGMPGKSIN  780
SMPEAKLAAP SKSEEYADPF LRRFFITGKS INSMPEAKLA APSKSEEYAD PFLRHFFMTG  840
KSINSMPEAK LAAPADGGHH LMMAKIMAYL LFAIRSQHIK VVNRDRTFSI QTEGTMELLE  900
SILASKSEEY ADPSLRHFFM MNNWKYLEVT NRPSDMDAVF GDDWLQKIRA KVQQNIELYQ  960
RNSWDKVLEF LKLDINDSME VNFVVDLMKE KISLFNKHFT ETCRVQCTWS IHYYKLRKEM  1020
IESLKNTLLP AYGIFIGRFQ DFLKTDAYEY IEYGMFDIHD ILDNLFLGNK KNK*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4rl5_A2e-562981073137562Exocyst complex component EXO70A1
4rl5_B2e-562981073137562Exocyst complex component EXO70A1
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtComponent of an exocyst subcomplex specifically involved in autophagy-related, Golgi-independent membrane traffic to the vacuole. Regulates autophagosome formation and autophagy-related Golgi-independent import into the vacuole. Positive regulator of both abscisic acid (ABA)-promoted and mannitol (drought)-promoted stomatal closure (PubMed:27956469). {ECO:0000269|PubMed:23944713, ECO:0000269|PubMed:27956469}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapMedtr5g073620.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAC1447250.0AC144725.16 Medicago truncatula clone mth2-7m17, complete sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_003615896.20.0uncharacterized protein LOC11409580
SwissprotQ9FGH91e-114E70B1_ARATH; Exocyst complex component EXO70B1
TrEMBLG7JZS80.0G7JZS8_MEDTR; Exocyst subunit exo70 family protein
STRINGAES988540.0(Medicago truncatula)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF174145
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G40740.11e-24WRKY DNA-binding protein 55
Publications ? help Back to Top
  1. Synek L, et al.
    AtEXO70A1, a member of a family of putative exocyst subunits specifically expanded in land plants, is important for polar growth and plant development.
    Plant J., 2006. 48(1): p. 54-72
    [PMID:16942608]
  2. Li S, et al.
    Expression and functional analyses of EXO70 genes in Arabidopsis implicate their roles in regulating cell type-specific exocytosis.
    Plant Physiol., 2010. 154(4): p. 1819-30
    [PMID:20943851]
  3. Wang J, et al.
    EXPO, an exocyst-positive organelle distinct from multivesicular endosomes and autophagosomes, mediates cytosol to cell wall exocytosis in Arabidopsis and tobacco cells.
    Plant Cell, 2010. 22(12): p. 4009-30
    [PMID:21193573]
  4. Young ND, et al.
    The Medicago genome provides insight into the evolution of rhizobial symbioses.
    Nature, 2011. 480(7378): p. 520-4
    [PMID:22089132]
  5. Kulich I, et al.
    Arabidopsis exocyst subcomplex containing subunit EXO70B1 is involved in autophagy-related transport to the vacuole.
    Traffic, 2013. 14(11): p. 1155-65
    [PMID:23944713]
  6. Stegmann M, et al.
    The exocyst subunit Exo70B1 is involved in the immune response of Arabidopsis thaliana to different pathogens and cell death.
    Plant Signal Behav, 2013. 8(12): p. e27421
    [PMID:24389869]
  7. Tzfadia O,Galili G
    The Arabidopsis exocyst subcomplex subunits involved in a golgi-independent transport into the vacuole possess consensus autophagy-associated atg8 interacting motifs.
    Plant Signal Behav, 2013. 8(10): p. doi: 10.4161/psb.26732
    [PMID:24494242]
  8. Zhao T, et al.
    A truncated NLR protein, TIR-NBS2, is required for activated defense responses in the exo70B1 mutant.
    PLoS Genet., 2015. 11(1): p. e1004945
    [PMID:25617755]
  9. Hong D,Jeon BW,Kim SY,Hwang JU,Lee Y
    The ROP2-RIC7 pathway negatively regulates light-induced stomatal opening by inhibiting exocyst subunit Exo70B1 in Arabidopsis.
    New Phytol., 2016. 209(2): p. 624-35
    [PMID:26451971]
  10. Seo DH,Ahn MY,Park KY,Kim EY,Kim WT
    The N-Terminal UND Motif of the Arabidopsis U-Box E3 Ligase PUB18 Is Critical for the Negative Regulation of ABA-Mediated Stomatal Movement and Determines Its Ubiquitination Specificity for Exocyst Subunit Exo70B1.
    Plant Cell, 2016. 28(12): p. 2952-2973
    [PMID:27956469]
  11. Sabol P,Kulich I,Žárský V
    RIN4 recruits the exocyst subunit EXO70B1 to the plasma membrane.
    J. Exp. Bot., 2017. 68(12): p. 3253-3265
    [PMID:28338727]
  12. Liu N, et al.
    CALCIUM-DEPENDENT PROTEIN KINASE5 Associates with the Truncated NLR Protein TIR-NBS2 to Contribute to exo70B1-Mediated Immunity.
    Plant Cell, 2017. 29(4): p. 746-759
    [PMID:28351987]