PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MDP0000200319
Organism
Malus domestica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus
Family AP2
Protein Properties Length: 469aa    MW: 51885.9 Da    PI: 8.5607
Description AP2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MDP0000200319genomeGDRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP253.75.2e-17136185155
            AP2   1 sgykGVrwdkkrgrWvAeIrdpsengkr.krfslgkfgtaeeAakaaiaarkkleg 55 
                    s+y+GV++++++grW+++I+d      + k+++lg f+ta  Aa+a+++a+ k++g
  MDP0000200319 136 SQYRGVTFYRRTGRWESHIWD------CgKQVYLGGFDTAHAAARAYDRAAIKFRG 185
                    78*******************......55************************997 PP
2AP240.85.4e-13228278155
            AP2   1 sgykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 
                    s+++GV+ +k  grW+A+   +     +k+++lg f+++ eAa+a+++a+ k +g
  MDP0000200319 228 SKFRGVTLHK-CGRWEARMGQF--L-GKKYVYLGLFDSEIEAARAYDKAAIKCNG 278
                    79********.7******5553..2.26**********99**********99776 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF541717.19E-16136195IPR016177DNA-binding domain
PfamPF008473.1E-9136185IPR001471AP2/ERF domain
CDDcd000183.47E-11137195No hitNo description
SMARTSM003801.7E-31137199IPR001471AP2/ERF domain
Gene3DG3DSA:3.30.730.104.8E-17137193IPR001471AP2/ERF domain
PROSITE profilePS5103217.662137193IPR001471AP2/ERF domain
CDDcd000181.59E-24228286No hitNo description
SuperFamilySSF541713.86E-16228287IPR016177DNA-binding domain
PfamPF008479.1E-9228278IPR001471AP2/ERF domain
SMARTSM003806.7E-31229292IPR001471AP2/ERF domain
PROSITE profilePS5103215.027229286IPR001471AP2/ERF domain
Gene3DG3DSA:3.30.730.102.6E-15229287IPR001471AP2/ERF domain
PRINTSPR003671.4E-5230241IPR001471AP2/ERF domain
PRINTSPR003671.4E-5268288IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 469 aa     Download sequence    Send to blast
MLDLNLGFVS RXDVSMSQNK LLTPSPVECS GSFNSSSNLT VTGDDDDDST TLNFLAPNDG  60
VSANHQDGRR TIQLFPLAQS VSSSSSSSAA SKKXWLGLSS GSRLELEPTY YAPAXPRIAX  120
PQQVKKSRRG PRSRSSQYRG VTFYRRTGRW ESHIWDCGKQ VYLGGFDTAH AAARAYDRAA  180
IKFRGIEADI NFSVSDYEDD IKQMSSFTKE EFVHILRRQS TGFSRGSSKF RGVTLHKCGR  240
WEARMGQFLG KKYVYLGLFD SEIEAARAYD KAAIKCNGRE AVTNFDRSSY DGEIMSEANN  300
EGSHQSLDLN LGIAPPLVSE IQKENMNLRS FPFQLGCDDI PIHLRARNEI SVPAPMRSHL  360
SHGSIVASKE PPIMSNMNSS FFPFHMERAT EKSMDVNSFP NWAWQVQGLN GGATSMPLFS  420
AAASSGFPSS TATSSSSAVT QLHFPNTAIL HHHFSPSFTN NIPHFYCRS
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: First detected in the boundary region of the shoot apical meristem (SAM) and the surrounding sheath. Expressed at low levels in vegetative organs, mostly in the sheaths. In inflorescence tissues, observed in the branch meristem and spikelet meristem regions, as well as in their vasculature and surrounding sheath (PubMed:17144896). Accumulates in incipient rudimentary- and empty-glume primordia (PubMed:22003982). Highly abundant in young developing panicles, but becomes later present at low levels in developing panicles and seeds. Found primarily in the boundary region of glume primordia (PubMed:17144896). {ECO:0000269|PubMed:17144896, ECO:0000269|PubMed:22003982}.
UniprotTISSUE SPECIFICITY: Highly expressed in seedlings and developing panicles (PubMed:17144896, PubMed:20017947, PubMed:22003982). Mostly expressed in newly emerging spikelet meristems and, at low levels, in shoots, roots, panicles, mature spikelets and sheaths (PubMed:17144896). {ECO:0000269|PubMed:17144896, ECO:0000269|PubMed:20017947, ECO:0000269|PubMed:22003982}.
Functional Description ? help Back to Top
Source Description
UniProtProbable transcription factor (By similarity). Involved in spikelet transition (Probable). Together with IDS1, controls synergistically inflorescence architecture and floral meristem establishment via the regulation of spatio-temporal expression of B- and E-function floral organ identity genes in the lodicules and of spikelet meristem genes (PubMed:22003982). Prevents lemma and palea elongation as well as grain growth (PubMed:28066457). Regulates the transition from spikelet meristem to floral meristem, spikelet meristem determinancy and the floral organ development (PubMed:17144896). {ECO:0000250|UniProtKB:P47927, ECO:0000269|PubMed:17144896, ECO:0000269|PubMed:22003982, ECO:0000269|PubMed:28066457, ECO:0000305|PubMed:26631749}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Target of miR172 microRNA mediated cleavage, particularly during floral organ development. {ECO:0000269|PubMed:20017947, ECO:0000269|PubMed:22003982, ECO:0000305|PubMed:26631749, ECO:0000305|PubMed:28066457}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_008369704.20.0APETALA2-like protein 3 isoform X1
RefseqXP_028956954.10.0APETALA2-like protein 3 isoform X1
SwissprotQ8H4431e-107AP23_ORYSJ; APETALA2-like protein 3
TrEMBLA0A498K4Z00.0A0A498K4Z0_MALDO; Uncharacterized protein
STRINGXP_008369704.10.0(Malus domestica)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF105813041
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G28550.31e-99related to AP2.7
Publications ? help Back to Top
  1. Lee DY,An G
    Two AP2 family genes, supernumerary bract (SNB) and Osindeterminate spikelet 1 (OsIDS1), synergistically control inflorescence architecture and floral meristem establishment in rice.
    Plant J., 2012. 69(3): p. 445-61
    [PMID:22003982]
  2. Wang L, et al.
    Coordinated regulation of vegetative and reproductive branching in rice.
    Proc. Natl. Acad. Sci. U.S.A., 2015. 112(50): p. 15504-9
    [PMID:26631749]
  3. Dai Z,Wang J,Zhu M,Miao X,Shi Z
    OsMADS1 Represses microRNA172 in Elongation of Palea/Lemma Development in Rice.
    Front Plant Sci, 2016. 7: p. 1891
    [PMID:28066457]