PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MDP0000163645
Organism
Malus domestica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus
Family AP2
Protein Properties Length: 477aa    MW: 52806.3 Da    PI: 7.7363
Description AP2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MDP0000163645genomeGDRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP2561e-17136185155
            AP2   1 sgykGVrwdkkrgrWvAeIrdpsengkr.krfslgkfgtaeeAakaaiaarkkleg 55 
                    s+y+GV++++++grW+++I+d      + k+++lg f+ta+ Aa+a+++a+ k++g
  MDP0000163645 136 SQYRGVTFYRRTGRWESHIWD------CgKQVYLGGFDTAQSAARAYDRAAIKFRG 185
                    78*******************......55************************998 PP
2AP241.63.1e-13228278155
            AP2   1 sgykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 
                    s+++GV+ +k  grW+A+   +     rk+++lg f+++ eAa+a+++a+ + +g
  MDP0000163645 228 SKFRGVTLHK-CGRWEARMGQFM---GRKYIYLGLFDSEIEAARAYDQAAIECNG 278
                    79********.7******66642...25**********99**********98766 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF541714.64E-16136195IPR016177DNA-binding domain
PfamPF008471.0E-9136185IPR001471AP2/ERF domain
CDDcd000182.96E-23137195No hitNo description
Gene3DG3DSA:3.30.730.101.2E-17137193IPR001471AP2/ERF domain
SMARTSM003801.1E-31137199IPR001471AP2/ERF domain
PROSITE profilePS5103217.701137193IPR001471AP2/ERF domain
SuperFamilySSF541716.54E-16228287IPR016177DNA-binding domain
PfamPF008474.0E-9228278IPR001471AP2/ERF domain
CDDcd000182.36E-23228288No hitNo description
Gene3DG3DSA:3.30.730.109.0E-15229287IPR001471AP2/ERF domain
SMARTSM003806.4E-31229292IPR001471AP2/ERF domain
PROSITE profilePS5103214.882229286IPR001471AP2/ERF domain
PRINTSPR003672.4E-5230241IPR001471AP2/ERF domain
PRINTSPR003672.4E-5268288IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 477 aa     Download sequence    Send to blast
MLDLNLGFVS HDVVPDSHHK LLSTTPIESS ESFNSSSNLT LAGDDDDNSA TLNFLAXNDD  60
VSADHYDGRR TIQLFPLAQS VRSSSSSSSA SKKQWLGLSS GSRLELEPIY YAPAKQWIAP  120
PQQVKKSRRG PRSRSSQYRG VTFYRRTGRW ESHIWDCGKQ VYLGGFDTAQ SAARAYDRAA  180
IKFRGTEADI NFSVSDYEDD IKQMSNFTKE EFVHILRRQS TGFSRGRSKF RGVTLHKCGR  240
WEARMGQFMG RKYIYLGLFD SEIEAARAYD QAAIECNGRE AVTNFDSSSY DGVLMSEANN  300
KGSHQNLDLN LGIAPPFVSE IQKENINLSS FPFQLGCDGI PIHTRARNEN SVPAPMRSQL  360
SHGSMVASEV HPIMSNMNSX FFPIHMERAM EKSMDVNSFP SWAWQLQDLN GGPTSMPLLS  420
TAASSGFPSS TATSSSSALM KSSIAVXWHG KIAVALPSAG DDHKFAVALF SMLQLRV
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: First detected in the boundary region of the shoot apical meristem (SAM) and the surrounding sheath. Expressed at low levels in vegetative organs, mostly in the sheaths. In inflorescence tissues, observed in the branch meristem and spikelet meristem regions, as well as in their vasculature and surrounding sheath (PubMed:17144896). Accumulates in incipient rudimentary- and empty-glume primordia (PubMed:22003982). Highly abundant in young developing panicles, but becomes later present at low levels in developing panicles and seeds. Found primarily in the boundary region of glume primordia (PubMed:17144896). {ECO:0000269|PubMed:17144896, ECO:0000269|PubMed:22003982}.
UniprotTISSUE SPECIFICITY: Highly expressed in seedlings and developing panicles (PubMed:17144896, PubMed:20017947, PubMed:22003982). Mostly expressed in newly emerging spikelet meristems and, at low levels, in shoots, roots, panicles, mature spikelets and sheaths (PubMed:17144896). {ECO:0000269|PubMed:17144896, ECO:0000269|PubMed:20017947, ECO:0000269|PubMed:22003982}.
Functional Description ? help Back to Top
Source Description
UniProtProbable transcription factor (By similarity). Involved in spikelet transition (Probable). Together with IDS1, controls synergistically inflorescence architecture and floral meristem establishment via the regulation of spatio-temporal expression of B- and E-function floral organ identity genes in the lodicules and of spikelet meristem genes (PubMed:22003982). Prevents lemma and palea elongation as well as grain growth (PubMed:28066457). Regulates the transition from spikelet meristem to floral meristem, spikelet meristem determinancy and the floral organ development (PubMed:17144896). {ECO:0000250|UniProtKB:P47927, ECO:0000269|PubMed:17144896, ECO:0000269|PubMed:22003982, ECO:0000269|PubMed:28066457, ECO:0000305|PubMed:26631749}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Target of miR172 microRNA mediated cleavage, particularly during floral organ development. {ECO:0000269|PubMed:20017947, ECO:0000269|PubMed:22003982, ECO:0000305|PubMed:26631749, ECO:0000305|PubMed:28066457}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_008387676.20.0APETALA2-like protein 3 isoform X1
SwissprotQ8H4431e-106AP23_ORYSJ; APETALA2-like protein 3
TrEMBLA0A498IET30.0A0A498IET3_MALDO; Uncharacterized protein
STRINGXP_008387676.10.0(Malus domestica)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF105813041
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G28550.32e-93related to AP2.7
Publications ? help Back to Top
  1. Lee DY,An G
    Two AP2 family genes, supernumerary bract (SNB) and Osindeterminate spikelet 1 (OsIDS1), synergistically control inflorescence architecture and floral meristem establishment in rice.
    Plant J., 2012. 69(3): p. 445-61
    [PMID:22003982]
  2. Wang L, et al.
    Coordinated regulation of vegetative and reproductive branching in rice.
    Proc. Natl. Acad. Sci. U.S.A., 2015. 112(50): p. 15504-9
    [PMID:26631749]
  3. Dai Z,Wang J,Zhu M,Miao X,Shi Z
    OsMADS1 Represses microRNA172 in Elongation of Palea/Lemma Development in Rice.
    Front Plant Sci, 2016. 7: p. 1891
    [PMID:28066457]