PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MDP0000137733
Organism
Malus domestica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus
Family NAC
Protein Properties Length: 404aa    MW: 45198.9 Da    PI: 8.9232
Description NAC family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MDP0000137733genomeGDRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1NAM41.25.1e-1395141146
            NAM   1 lppGfrFhPtdeelvveyLkkkvegkk.leleevikevdiykvePwd 46 
                    + pGfrF+Ptdeel+++yLk+k+eg    +  evi+evdi+ +eP d
  MDP0000137733  95 MFPGFRFSPTDEELISYYLKNKLEGPVpGKSVEVISEVDICXFEPCD 141
                    579*********************9886444588***********87 PP
2NAM93.14.6e-2920728450128
            NAM  50 kvkaeekewyfFskrdkkyatgkrknratksgyWkatgkdkevlskkgelvglkktLvfykgrapkgektdWvmheyrl 128
                    +v ++e+ew+fFs+r +ky++g++++rat+ gyWkatgk+++++s +++++g+k+tLvf+ grapkge+t+W+mhey +
  MDP0000137733 207 SVIQSENEWFFFSPRGRKYPNGSQSRRATEFGYWKATGKERNIKS-SSNVIGTKRTLVFHIGRAPKGERTEWIMHEYCI 284
                    4456789**************************************.999****************************86 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF1019416.28E-1385145IPR003441NAC domain
PROSITE profilePS5100542.76895300IPR003441NAC domain
PfamPF023657.3E-2497283IPR003441NAC domain
SuperFamilySSF1019412.48E-33207299IPR003441NAC domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 404 aa     Download sequence    Send to blast
MLCSIGVSKT LKNLAALSQT DQPGHAIVRQ RRQEKAKHKT QTQTQTQLSV KALLTFMSLL  60
LFLAKKRNSR ETETKKEEMG AVSKEAQLSI AASSMFPGFR FSPTDEELIS YYLKNKLEGP  120
VPGKSVEVIS EVDICXFEPC DSVELESMFY GVFEFLVNVF VTFYRPLFIL SRALTLGTAW  180
SSLQYRLGLN LGTMRLHDYG FSILSKSVIQ SENEWFFFSP RGRKYPNGSQ SRRATEFGYW  240
KATGKERNIK SSSNVIGTKR TLVFHIGRAP KGERTEWIMH EYCINDKPQD SMVVCRLRKN  300
SEFRLNDTTN GGSSSRTPLS TMQNDGSAVS EIGNDQGDKA VECNSKKSTS SHDSHSIEQI  360
DSASDSYPKP VTDAMQTDSN GHQKVVEINS AAPPASLQAW ESII
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
3swm_A1e-2619129952167NAC domain-containing protein 19
3swm_B1e-2619129952167NAC domain-containing protein 19
3swm_C1e-2619129952167NAC domain-containing protein 19
3swm_D1e-2619129952167NAC domain-containing protein 19
3swp_A1e-2619129952167NAC domain-containing protein 19
3swp_B1e-2619129952167NAC domain-containing protein 19
3swp_C1e-2619129952167NAC domain-containing protein 19
3swp_D1e-2619129952167NAC domain-containing protein 19
Search in ModeBase
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Accumulates in imbibed seeds (PubMed:19704545). Detected in early stages of seed development, especially in the basal tip of immature embryo. Particularly expressed in vascular tissues of inflorescence stems, roots, leaves and petioles (PubMed:17410378). {ECO:0000269|PubMed:17410378, ECO:0000269|PubMed:19704545}.
UniprotTISSUE SPECIFICITY: Expressed in seeds, leaves, roots and inflorescence (PubMed:17410378). Expressed in roots, rosette leaves, cauline leaves, shoot apex, stems and flowers (PubMed:17158162). {ECO:0000269|PubMed:17158162, ECO:0000269|PubMed:17410378}.
Functional Description ? help Back to Top
Source Description
UniProtTranscriptional activator activated by proteolytic cleavage through regulated intramembrane proteolysis (RIP), probably via metalloprotease activity. Regulates gibberellic acid-mediated salt-responsive repression of seed germination and flowering via FT, thus delaying seed germination under high salinity conditions. {ECO:0000269|PubMed:17410378, ECO:0000269|PubMed:18363782, ECO:0000269|PubMed:19704528, ECO:0000269|PubMed:19704545}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By high salt stress (PubMed:19704545, PubMed:17410378, PubMed:18363782, PubMed:19704528). Repressed by gibberellic acid (GA), but induced by the GA biosynthetic inhibitor paclabutrazol (PAC) (PubMed:18363782). Accumulates transiently in seeds upon imbibition (PubMed:19704545, PubMed:17410378, PubMed:18363782, PubMed:19704528). Induced by drought stress (PubMed:17158162). {ECO:0000269|PubMed:17158162, ECO:0000269|PubMed:17410378, ECO:0000269|PubMed:18363782, ECO:0000269|PubMed:19704528, ECO:0000269|PubMed:19704545}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_028944504.11e-170NAC domain-containing protein 40-like
SwissprotQ9XIN71e-53NAC40_ARATH; NAC domain-containing protein 40
TrEMBLA0A498IMV01e-152A0A498IMV0_MALDO; Uncharacterized protein
STRINGXP_008372812.11e-175(Malus domestica)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF73153346
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G27300.15e-55NTM1-like 8
Publications ? help Back to Top
  1. Liang M, et al.
    Subcellular Distribution of NTL Transcription Factors in Arabidopsis thaliana.
    Traffic, 2015. 16(10): p. 1062-74
    [PMID:26201836]
  2. Tian H, et al.
    NTL8 Regulates Trichome Formation in Arabidopsis by Directly Activating R3 MYB Genes TRY and TCL1.
    Plant Physiol., 2017. 174(4): p. 2363-2375
    [PMID:28649093]