PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Lus10009780

Organism

Linum usitatissimum

Taxonomic ID

4006

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Linaceae; Linum

Family

MYB

Protein Properties

Length: 289aa MW: 32527.6 Da PI: 5.3171

Description

MYB family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Lus10009780	genome	BGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Myb_DNA-binding	41	4.3e-13	10	55	1	46
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHH CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqk 46 +g+W +eEd+ l++ v+++G++ W++I ++ + Rt+k+c++rw + Lus10009780 10 KGPWKAEEDQVLINHVHKYGPREWSSIRSKGLLQRTGKSCRLRWVN 55 79***********************8887799********87 PP
2	Myb_DNA-binding	40.6	5.8e-13	66	105	3	44
SS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHH CS Myb_DNA-binding 3 rWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrw 44 ++++eE+ + +++ ++lG++ W++Ia ++ gRt++++k++w Lus10009780 66 KFSEEEQRIVIELQARLGNK-WAKIATYLA-GRTDNDVKNFW 105 79****************.*****.********* PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.10.60	2.2E-21	3	58	IPR009057	Homeodomain-like
PROSITE profile	PS51294	20.798	5	61	IPR017930	Myb domain
SuperFamily	SSF46689	4.67E-27	8	105	IPR009057	Homeodomain-like
SMART	SM00717	6.7E-10	9	59	IPR001005	SANT/Myb domain
Pfam	PF00249	1.3E-11	10	55	IPR001005	SANT/Myb domain
CDD	cd00167	8.05E-10	12	57	No hit	No description
Gene3D	G3DSA:1.10.10.60	5.5E-17	59	111	IPR009057	Homeodomain-like
PROSITE profile	PS51294	18.221	62	113	IPR017930	Myb domain
SMART	SM00717	6.0E-12	63	111	IPR001005	SANT/Myb domain
CDD	cd00167	2.60E-9	66	105	No hit	No description
Pfam	PF00249	8.7E-12	66	105	IPR001005	SANT/Myb domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0048235	Biological Process	pollen sperm cell differentiation
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 289 aa Download sequence Send to blast
MEVKNEEVRK GPWKAEEDQV LINHVHKYGP REWSSIRSKG LLQRTGKSCR LRWVNKLRPN 60 LKNGCKFSEE EQRIVIELQA RLGNKWAKIA TYLAGRTDND VKNFWSSRQK RLARLNNNNS 120 CNNSSASNSS KTTKKARTKM SSSTMEEEEA EEEKEEEGPS SSSSKKVQLL CSSNTEEPMK 180 TVPLSVPIVK PELVPVESEP VNPFPQPQPP ELISFSPESQ ELLARLEDPF FFNVFGIPQL 240 GDIPELSLGP PLSDHPLPSC MTGGIDDDDD FPADLFDQID RLPSPSHW*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1h8a_C	2e-30	2	111	19	126	MYB TRANSFORMING PROTEIN
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Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that acts as a positive regulator of male germline development by promoting both gametic cell specification and cell cycle progression (PubMed:15694308, PubMed:15618418, PubMed:19300502, PubMed:21285328). Binds to canonical MYB sites 5'-AACCGTC-3', 5'-AAACCGC-3' and 5'-AACCGT-3' in promoters to trigger the expression of male germline-specific or enriched genes (e.g. MGH3, GEX2 and GCS1), including those required for fertilization (PubMed:21285328, PubMed:19300502). Required for sperm cell specification leading to pollen maturation by activating a germline-specific regulon (PubMed:21285328, PubMed:15694308, PubMed:15618418, PubMed:19300502). Involved in pollen mitosis entry at G2-M transition via the regulation of CYCB1-1, DAZ1 and DAZ2 expression (PubMed:15618418, PubMed:19300502, PubMed:24876252). {ECO:0000269\|PubMed:15618418, ECO:0000269\|PubMed:15694308, ECO:0000269\|PubMed:19300502, ECO:0000269\|PubMed:21285328, ECO:0000269\|PubMed:24876252}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Lus10009780

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Repressed by the microRNA 159 (miR159); the production of miR159 is stimulated by the anaphase promoting complex/cyclosome (APC/C) (PubMed:21441434). Activated by ARID1 in male germline cells via specific histone acetylation regulation (e.g. H3K9Ac) (PubMed:25057814). {ECO:0000269\|PubMed:21441434, ECO:0000269\|PubMed:25057814}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_021670814.1	2e-98	transcription factor DUO1-like isoform X2
Swissprot	A0A178VEK7	4e-84	DUO1_ARATH; Transcription factor DUO1
TrEMBL	A0A0E3NAD0	7e-97	A0A0E3NAD0_JATCU; MYB125
STRING	Lus10009780	0.0	(Linum usitatissimum)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF3693	31	64

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G60460.1	4e-69	MYB family protein

Link Out ? help Back to Top
Phytozome	Lus10009780

Publications ? help Back to Top
Zheng B,He H,Zheng Y,Wu W,McCormick S An ARID domain-containing protein within nuclear bodies is required for sperm cell formation in Arabidopsis thaliana. PLoS Genet., 2014. 10(7): p. e1004421 [PMID:25057814] Peters B, et al. A Conserved cis-Regulatory Module Determines Germline Fate through Activation of the Transcription Factor DUO1 Promoter. Plant Physiol., 2017. 173(1): p. 280-293 [PMID:27624837] Zheng Z, et al. Target RNA Secondary Structure Is a Major Determinant of miR159 Efficacy. Plant Physiol., 2017. 174(3): p. 1764-1778 [PMID:28515145]