PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

KFK30384.1

Organism

Arabis alpina

Taxonomic ID

50452

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Arabideae; Arabis

Family

GRF

Protein Properties

Length: 515aa MW: 56768.1 Da PI: 8.8371

Description

GRF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
KFK30384.1	genome	MPIPBR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	WRC	78.6	6.1e-25	212	255	1	44
WRC 1 daepgrCrRtDGKkWRCsrrvlegkklCErHlhrgrsrsrkske 44 d+epgrCrRtDGKkWRCsr++++++k+CErH++rgr+rsrk++e KFK30384.1 212 DPEPGRCRRTDGKKWRCSRDAVPDQKYCERHINRGRHRSRKPVE 255 79***************************************998 PP
2	QLQ	50.4	6.5e-18	148	184	1	37
QLQ 1 saFTaaQlqlLksQilAyKyLaanqPvPpeLlqaiqk 37 ++FT +Q+++L+ Q+l+yKy+ an+PvP+ Ll i+k KFK30384.1 148 GPFTLTQWAELELQALIYKYITANVPVPSSLLISIKK 184 59******************************99986 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM00951	7.5E-11	148	184	IPR014978	Glutamine-Leucine-Glutamine, QLQ
PROSITE profile	PS51666	20.749	149	184	IPR014978	Glutamine-Leucine-Glutamine, QLQ
Pfam	PF08880	2.0E-12	149	182	IPR014978	Glutamine-Leucine-Glutamine, QLQ
PROSITE profile	PS51667	25.77	212	256	IPR014977	WRC domain
Pfam	PF08879	3.3E-21	213	255	IPR014977	WRC domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0008285	Biological Process	negative regulation of cell proliferation
GO:0048364	Biological Process	root development
GO:0048366	Biological Process	leaf development
GO:0005634	Cellular Component	nucleus
GO:0005524	Molecular Function	ATP binding

Sequence ? help Back to Top
Protein Sequence Length: 515 aa Download sequence Send to blast
MDIETHIHGS VTKELRGTKQ DRSIFESEEF LQRSSKLSRT TQEEQEEENL SSCSKTMSFH 60 QGIPLMRSST TSLLSSDSRR QEHMLSFSDK PEPLDFTKHV GLEINNNNKN SLSPFLAPPS 120 YYRSSGGGYG SGGMMMSMEG NSLNGVKGPF TLTQWAELEL QALIYKYITA NVPVPSSLLI 180 SIKKSFYPYG SLPPSAFGWG AFHLGFAGGN MDPEPGRCRR TDGKKWRCSR DAVPDQKYCE 240 RHINRGRHRS RKPVEVQSSH TVTPAASKAV TTPLQSVVTK GNARASSKNG SLAIGGQYIN 300 PSTDSLPNNR VQNPLGSSIY PSMVNIQSKE SPIVHQKHRN NNNNPFEFGH ISSDSLLNPN 360 SAKSYGSSYL DFSSNHDKQH PGNLNHNSWP EELKPDWTQL SMAIPITSSS PSSTHNTQDK 420 LTPSPLRLSR EVDLSIQTEE TTLEPPVKKV NTWIPISWGN SLGGPLGEVL NSTTNSPTGV 480 LQKSTFCSLS NSSSVSSPIA ENNNRNNGDY FHYTT

Sequence ? help Back to Top

Protein Sequence Length: 515 aa Download sequence Send to blast

MDIETHIHGS VTKELRGTKQ DRSIFESEEF LQRSSKLSRT TQEEQEEENL SSCSKTMSFH  60
QGIPLMRSST TSLLSSDSRR QEHMLSFSDK PEPLDFTKHV GLEINNNNKN SLSPFLAPPS  120
YYRSSGGGYG SGGMMMSMEG NSLNGVKGPF TLTQWAELEL QALIYKYITA NVPVPSSLLI  180
SIKKSFYPYG SLPPSAFGWG AFHLGFAGGN MDPEPGRCRR TDGKKWRCSR DAVPDQKYCE  240
RHINRGRHRS RKPVEVQSSH TVTPAASKAV TTPLQSVVTK GNARASSKNG SLAIGGQYIN  300
PSTDSLPNNR VQNPLGSSIY PSMVNIQSKE SPIVHQKHRN NNNNPFEFGH ISSDSLLNPN  360
SAKSYGSSYL DFSSNHDKQH PGNLNHNSWP EELKPDWTQL SMAIPITSSS PSSTHNTQDK  420
LTPSPLRLSR EVDLSIQTEE TTLEPPVKKV NTWIPISWGN SLGGPLGEVL NSTTNSPTGV  480
LQKSTFCSLS NSSSVSSPIA ENNNRNNGDY FHYTT

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that plays a role in the regulation of cell expansion in leaf and cotyledons tissues. Component of a network formed by miR396, the GRFs and their interacting factors (GIFs) acting in the regulation of meristem function, at least partially through the control of cell proliferation. {ECO:0000269\|PubMed:12974814, ECO:0000269\|PubMed:15326298, ECO:0000269\|PubMed:20023165, ECO:0000269\|PubMed:21036927}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	KFK30384.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: microRNA 396 (miR396a or miR396b) negatively regulates growth-regulating factors (GRF1-4 and GRF7-9). {ECO:0000269\|PubMed:15200956, ECO:0000269\|PubMed:19453503, ECO:0000269\|PubMed:20023165}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	NP_195488.2	0.0	growth-regulating factor 2
Swissprot	Q8L8A8	0.0	GRF2_ARATH; Growth-regulating factor 2
TrEMBL	A0A087GKI2	0.0	A0A087GKI2_ARAAL; Uncharacterized protein
STRING	A0A087GKI2	0.0	(Arabis alpina)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM1454	28	86

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G37740.1	0.0	growth-regulating factor 2

Publications ? help Back to Top
Casadevall R,Rodriguez RE,Debernardi JM,Palatnik JF,Casati P Repression of growth regulating factors by the microRNA396 inhibits cell proliferation by UV-B radiation in Arabidopsis leaves. Plant Cell, 2013. 25(9): p. 3570-83 [PMID:24076976] Liu J,Rice JH,Chen N,Baum TJ,Hewezi T Synchronization of developmental processes and defense signaling by growth regulating transcription factors. PLoS ONE, 2014. 9(5): p. e98477 [PMID:24875638] Cao Y,Han Y,Jin Q,Lin Y,Cai Y Comparative Genomic Analysis of the GRF Genes in Chinese Pear (Pyrus bretschneideri Rehd), Poplar (Populous), Grape (Vitis vinifera), Arabidopsis and Rice (Oryza sativa). Front Plant Sci, 2016. 7: p. 1750 [PMID:27933074]