PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID HL.SW.v1.0.G020650.1
Organism
Humulus lupulus
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Cannabaceae; Humulus
Family AP2
Protein Properties Length: 370aa    MW: 40584.2 Da    PI: 7.6025
Description AP2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
HL.SW.v1.0.G020650.1genomeHOPBASEView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP237.46.6e-12229285155
                   AP2   1 sgykGVrwdkkrgrWvAeIrd.pseng..kr.krfslgkfgtaeeAakaaiaarkkleg 55 
                           s y+GV++++++gr++A+++d  +     ++ k  + g ++ +e+Aa+a++ a++k++g
  HL.SW.v1.0.G020650.1 229 SIYRGVTRHRWTGRYEAHLWDnSCR-RegQSrKGRQ-GGYDKEEKAARAYDLAALKYWG 285
                           57*******************5444.2455536655.779999**************98 PP
2AP236.98.8e-12328370146
                   AP2   1 sgykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaa 46 
                           s y+GV+++++ grW A+I  +     +k  +lg+f t eeAa+a+
  HL.SW.v1.0.G020650.1 328 SIYRGVTRHHQHGRWQARIGRVAG---NKDLYLGTFSTQEEAAEAY 370
                           57****************988532...5****************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
CDDcd000189.75E-19229294No hitNo description
PfamPF008472.3E-9229285IPR001471AP2/ERF domain
SuperFamilySSF541714.38E-15229294IPR016177DNA-binding domain
SMARTSM003802.6E-22230299IPR001471AP2/ERF domain
Gene3DG3DSA:3.30.730.101.8E-12230293IPR001471AP2/ERF domain
PROSITE profilePS5103217.477230293IPR001471AP2/ERF domain
CDDcd000184.69E-14328370No hitNo description
PfamPF008472.0E-7328370IPR001471AP2/ERF domain
SuperFamilySSF541712.16E-10328370IPR016177DNA-binding domain
SMARTSM003805.9E-8329370IPR001471AP2/ERF domain
Gene3DG3DSA:3.30.730.105.8E-10329370IPR001471AP2/ERF domain
PROSITE profilePS5103214.17329370IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 370 aa     Download sequence    Send to blast
MDSSSPSTTT AATTTTNTPH HHQNWLAFSL SNHPANLHSP HPLSLFQNPF TPNHHHHHHH  60
HHAEDHQDAS STDLAMFTGG GGGGGSGGGA PKLEDFLGGG PASSNGDQSL LCNNNNQFAA  120
VDQTTVQSLS SGNCATEADL YESELKTIAA SFLHGFNSHI NTNNMISNPS NNNNNNNNLM  180
SIINNNNNQR QIEVSPSCQL ATPLSAVAPV VDSPVSSKKT VDTFGQRTSI YRGVTRHRWT  240
GRYEAHLWDN SCRREGQSRK GRQGGYDKEE KAARAYDLAA LKYWGPTTTT NFPVCNYEKE  300
LEEMTNMTRQ EFVASLRRKS SGFSRGASIY RGVTRHHQHG RWQARIGRVA GNKDLYLGTF  360
STQEEAAEAY
Functional Description ? help Back to Top
Source Description
UniProtProbably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity). Involved in the regulation of floral organs size. {ECO:0000250, ECO:0000269|PubMed:15988559}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_021810080.11e-127AP2-like ethylene-responsive transcription factor AIL5
SwissprotQ6PQQ31e-106AIL5_ARATH; AP2-like ethylene-responsive transcription factor AIL5
TrEMBLA0A2P5E1Y51e-154A0A2P5E1Y5_TREOI; AP2/ERF transcription factor
STRINGEMJ268261e-125(Prunus persica)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF49423152
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G57390.11e-102AINTEGUMENTA-like 5
Publications ? help Back to Top
  1. Todd J,Post-Beittenmiller D,Jaworski JG
    KCS1 encodes a fatty acid elongase 3-ketoacyl-CoA synthase affecting wax biosynthesis in Arabidopsis thaliana.
    Plant J., 1999. 17(2): p. 119-30
    [PMID:10074711]
  2. Molitor AM,Bu Z,Yu Y,Shen WH
    Arabidopsis AL PHD-PRC1 complexes promote seed germination through H3K4me3-to-H3K27me3 chromatin state switch in repression of seed developmental genes.
    PLoS Genet., 2014. 10(1): p. e1004091
    [PMID:24465219]
  3. Feng J,Chen D,Berr A,Shen WH
    ZRF1 Chromatin Regulators Have Polycomb Silencing and Independent Roles in Development.
    Plant Physiol., 2016. 172(3): p. 1746-1759
    [PMID:27630184]
  4. Santuari L, et al.
    The PLETHORA Gene Regulatory Network Guides Growth and Cell Differentiation in Arabidopsis Roots.
    Plant Cell, 2016. 28(12): p. 2937-2951
    [PMID:27920338]
  5. Du Y,Scheres B
    PLETHORA transcription factors orchestrate de novo organ patterning during Arabidopsis lateral root outgrowth.
    Proc. Natl. Acad. Sci. U.S.A., 2017. 114(44): p. 11709-11714
    [PMID:29078398]