PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID HL.SW.v1.0.G004152.1
Organism
Humulus lupulus
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Cannabaceae; Humulus
Family bZIP
Protein Properties Length: 780aa    MW: 84499.3 Da    PI: 6.7987
Description bZIP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
HL.SW.v1.0.G004152.1genomeHOPBASEView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1bZIP_143.57e-14269330162
                           XXXXCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
                bZIP_1   1 ekelkrerrkqkNReAArrsRqRKkaeieeLeekvkeLeaeNkaLkkeleelkkevaklkse 62 
                           e++ k+  r+++NRe+A+ sRqRKk ++eeLe+kv ++ +  ++L ++++ +  e a+l+++
  HL.SW.v1.0.G004152.1 269 EEDEKKKARLMRNRESAQLSRQRKKHYVEELEDKVRNMHSTITDLNSKISYIMAENATLRQQ 330
                           678899***************************************************99987 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM003385.9E-17269333IPR004827Basic-leucine zipper domain
PfamPF001704.6E-12270331IPR004827Basic-leucine zipper domain
PROSITE profilePS5021710.553271331IPR004827Basic-leucine zipper domain
SuperFamilySSF579592.5E-12273331No hitNo description
Gene3DG3DSA:1.20.5.1703.6E-17273331No hitNo description
CDDcd147047.81E-21274325No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0042538Biological Processhyperosmotic salinity response
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0005783Cellular Componentendoplasmic reticulum
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 780 aa     Download sequence    Send to blast
MADRVVADLP MRPSPNPSYG DFSAELESLP IPPLDHQFFS TDDALSDNFF SDLGLGFEEN  60
CEYELTFDDI EDLHLLSDTE DFLIPDGYDE ATGGSMYRDT DRGVDPTSEA AAGSKSASPD  120
SDTSIVSGVK DYDVAGYLNC QSSESGSYNG VYSRNSGDGK SNRAMDFASP DDHESGGPAS  180
SHGSGNCGSG VSEGVSSPVH SDNSDRDVSS NIFGDLKVKL ETGKNCMSKR KKEAEEGNGE  240
SRTSKFRRSS TPVENSRSHS QSTLNPVSEE DEKKKARLMR NRESAQLSRQ RKKHYVEELE  300
DKVRNMHSTI TDLNSKISYI MAENATLRQQ LGGGGGMCPP PYPGMYPHPP MAPMAYPWMP  360
CSPYVVKPQG SQVPLVPIPR LKPQQTVSTP KMKKSEKKTE GRAKKVASIS FLGLLFFILL  420
FGGLVPVVDV SFGGLGDKAP VGSDYFSGSF HDQHSGKFLS IDAHMNGSGE NKGVGISAAK  480
SDGFRETVEF VHQERGSQSK PGYGEFVRLG NESEPLVASL YVPRNEKLVK IDGNLIIHSV  540
LASEKTKASL AHSEKSNRET VLAIAKDLAP YTVHEPGNRG GHAPLYRNPT ERHKALASGA  600
SNTRKDHLQS NAADGRLQQW FREGLAGPLL SSGMCTEVFQ FDVSPASASG AIVPAPSVSN  660
VSAKHHQNTR QNTTRLKGGN RRILHRLAIP LAGSKFNITE EHVTKKSRKD DFQGNRSVSS  720
MVVSVLVDPR EAGDGDVDGM MKPKSLSRIF VVVLIDSVKY VTYSCVLPRV GPHIVTSWG*
Functional Description ? help Back to Top
Source Description
UniProtTranscriptional activator involved in salt and osmotic stress responses. Functions as a stress sensor and transducer in a signaling pathway that resembles an ER stress response. Following salt stress, BZIP17 is cleaved by SBT6.1 (S1P) and S2P at the C-terminus and the N-terminal bZIP component is translocated to the nucleus, where it activates the expression of salt stress response genes (PubMed:17662035). Functions as a stress sensor and transducer in ER stress signaling pathway. ER stress induces proteolysis of BZIP17 by SBT6.1 (S1P) and S2P, and the N-terminal bZIP component is translocated to the nucleus, where it activates the expression and production of ER chaperones, as well as protein involved in brassinosteroid (BR) signaling, which is required for stress acclimation and growth (PubMed:20876872). {ECO:0000269|PubMed:17662035, ECO:0000269|PubMed:20876872}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_010111098.10.0bZIP transcription factor 17
SwissprotO222081e-178BZP17_ARATH; bZIP transcription factor 17
TrEMBLA0A2P5BRI70.0A0A2P5BRI7_TREOI; Basic-leucine zipper transcription factor
STRINGXP_010111098.10.0(Morus notabilis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF74873448
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G40950.11e-162bZIP family protein
Publications ? help Back to Top
  1. Zhou SF, et al.
    Membrane-associated transcription factor peptidase, site-2 protease, antagonizes ABA signaling in Arabidopsis.
    New Phytol., 2015. 208(1): p. 188-97
    [PMID:25919792]
  2. Sagor GH, et al.
    The polyamine spermine induces the unfolded protein response via the MAPK cascade in Arabidopsis.
    Front Plant Sci, 2015. 6: p. 687
    [PMID:26442007]
  3. Ezer D, et al.
    The G-Box Transcriptional Regulatory Code in Arabidopsis.
    Plant Physiol., 2017. 175(2): p. 628-640
    [PMID:28864470]
  4. Kim JS,Yamaguchi-Shinozaki K,Shinozaki K
    ER-Anchored Transcription Factors bZIP17 and bZIP28 Regulate Root Elongation.
    Plant Physiol., 2018. 176(3): p. 2221-2230
    [PMID:29367234]
  5. Cifuentes-Esquivel N, et al.
    bZIP17 regulates the expression of genes related to seed storage and germination, reducing seed susceptibility to osmotic stress.
    J. Cell. Biochem., 2018. 119(8): p. 6857-6868
    [PMID:29693271]
  6. Guan P, et al.
    SENSITIVE TO SALT1, An Endoplasmic Reticulum-Localized Chaperone, Positively Regulates Salt Resistance.
    Plant Physiol., 2018. 178(3): p. 1390-1405
    [PMID:30287478]