PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID GRMZM2G124037_P01
Common NameLOC103647602, Zm.13245
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; PACMAD clade; Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea
Family ERF
Protein Properties Length: 264aa    MW: 27628.6 Da    PI: 5.144
Description ERF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
GRMZM2G124037_P01genomeMaizeSequenceView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP2491.5e-1563115155
                AP2   1 sgykGVrwdkkrgrWvAeIrdpseng.krkrfslgkfgtaeeAakaaiaarkkleg 55 
                        + ++GVr++   grWv+e+r+p   g + +r +lg++  ae Aa+a++aa+++l g
  GRMZM2G124037_P01  63 PVFRGVRRRGAAGRWVCEVRVP---GrRGARLWLGTYLAAEAAARAHDAAMLALQG 115
                        579******************9...6455***********************9987 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF008471.1E-1063115IPR001471AP2/ERF domain
SMARTSM003803.8E-1664130IPR001471AP2/ERF domain
PROSITE profilePS5103221.03564124IPR001471AP2/ERF domain
SuperFamilySSF541713.6E-1564126IPR016177DNA-binding domain
Gene3DG3DSA:3.30.730.101.2E-2464126IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 264 aa     Download sequence    Send to blast
MDTAGLVQHA TSSSSTSTSA SSSSSSSEQQ SKAAWPPSPA SSPQQPPKKR PAGRTKFRET  60
RHPVFRGVRR RGAAGRWVCE VRVPGRRGAR LWLGTYLAAE AAARAHDAAM LALQGRGAGR  120
LNFPDSARLL AVPPPSALPG LDDARRAALE AVAEFQRRSG AADEATSGAS PPSSSPSLPD  180
VSAAGSPAAA LEHVPVKADE AVALDLDGDV FEPDWFGDMD LELDAYYASL AEGLLVEPPP  240
PAAAWDHEDC CDSGAADVAL WSYY
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Zm.132450.0ovary
Expression -- Microarray ? help Back to Top
Source ID
Expression AtlasGRMZM2G124037
Functional Description ? help Back to Top
Source Description
UniProtTranscriptional activator that binds specifically to the DNA sequence 5'-[AG]CCGAC-3'. Binding to the C-repeat/DRE element mediates high salinity- and dehydration-inducible transcription. Confers resistance to high salt, cold and drought stress (By similarity). {ECO:0000250}.
UniProtTranscriptional activator that binds specifically to the DNA sequence 5'-[AG]CCGAC-3'. Binding to the C-repeat/DRE element mediates high salinity- and dehydration-inducible transcription. Confers resistance to high salt, cold and drought stress. {ECO:0000269|PubMed:12609047, ECO:0000269|PubMed:16284406}.
Function -- GeneRIF ? help Back to Top
  1. Expression analyses showed that ZmCBF3 was upregulated by both abscisic acid and low temperature, and was actively expressed during embryogenesis, suggesting that ZmCBF3 plays a role in stress response in maize.
    [PMID: 18713346]
  2. Results show cis-acting elements involved in the down-regulation of gene expression that was activated by cold stress suggesting suggest that PZmCBF3 might play a role in cold tolerance in maize.
    [PMID: 26030672]
Cis-element ? help Back to Top
SourceLink
PlantRegMapGRMZM2G124037_P01
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By high-salt and cold stress. {ECO:0000269|PubMed:12609047}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAF4504810.0AF450481.1 Zea mays DREB-like protein (DREB1A) mRNA, complete cds.
GenBankAY9647180.0AY964718.1 Zea mays cultivar Qi319 CBF3-like protein (CBF3) mRNA, complete cds.
GenBankAY9669020.0AY966902.1 Zea mays CRT/DRE binding factor (CBF3) gene, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_008670333.10.0DRE-binding protein 3
SwissprotA2Z3893e-52DRE1A_ORYSI; Dehydration-responsive element-binding protein 1A
SwissprotQ64MA14e-52DRE1A_ORYSJ; Dehydration-responsive element-binding protein 1A
TrEMBLA0A1D6ETC20.0A0A1D6ETC2_MAIZE; CBF3-like protein
STRINGGRMZM2G124037_P010.0(Zea mays)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MonocotsOGMP19636261
Representative plantOGRP6456520
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G51990.13e-19C-repeat-binding factor 4
Publications ? help Back to Top
  1. Kikuchi S, et al.
    Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice.
    Science, 2003. 301(5631): p. 376-9
    [PMID:12869764]
  2. Oh SJ,Kwon CW,Choi DW,Song SI,Kim JK
    Expression of barley HvCBF4 enhances tolerance to abiotic stress in transgenic rice.
    Plant Biotechnol. J., 2007. 5(5): p. 646-56
    [PMID:17614953]
  3. Xiao BZ, et al.
    Evaluation of seven function-known candidate genes for their effects on improving drought resistance of transgenic rice under field conditions.
    Mol Plant, 2009. 2(1): p. 73-83
    [PMID:19529831]
  4. Mito T,Seki M,Shinozaki K,Ohme-Takagi M,Matsui K
    Generation of chimeric repressors that confer salt tolerance in Arabidopsis and rice.
    Plant Biotechnol. J., 2011. 9(7): p. 736-46
    [PMID:21114612]
  5. Sun H, et al.
    ENAC1, a NAC transcription factor, is an early and transient response regulator induced by abiotic stress in rice (Oryza sativa L.).
    Mol. Biotechnol., 2012. 52(2): p. 101-10
    [PMID:22161313]
  6. Huang J, et al.
    A TFIIIA-type zinc finger protein confers multiple abiotic stress tolerances in transgenic rice (Oryza sativa L.).
    Plant Mol. Biol., 2012. 80(3): p. 337-50
    [PMID:22930448]
  7. Lourenço T, et al.
    Isolation and characterization of rice (Oryza sativa L.) E3-ubiquitin ligase OsHOS1 gene in the modulation of cold stress response.
    Plant Mol. Biol., 2013. 83(4-5): p. 351-63
    [PMID:23780733]
  8. Chen X, et al.
    The NAC family transcription factor OsNAP confers abiotic stress response through the ABA pathway.
    Plant Cell Physiol., 2014. 55(3): p. 604-19
    [PMID:24399239]
  9. Wang ST, et al.
    MicroRNA319 positively regulates cold tolerance by targeting OsPCF6 and OsTCP21 in rice (Oryza sativa L.).
    PLoS ONE, 2014. 9(3): p. e91357
    [PMID:24667308]
  10. Chen M,Zhao Y,Zhuo C,Lu S,Guo Z
    Overexpression of a NF-YC transcription factor from bermudagrass confers tolerance to drought and salinity in transgenic rice.
    Plant Biotechnol. J., 2015. 13(4): p. 482-91
    [PMID:25283804]
  11. Paul S,Gayen D,Datta SK,Datta K
    Dissecting root proteome of transgenic rice cultivars unravels metabolic alterations and accumulation of novel stress responsive proteins under drought stress.
    Plant Sci., 2015. 234: p. 133-43
    [PMID:25804816]
  12. Liu J, et al.
    Functional Analysis of the Maize C-Repeat/DRE Motif-Binding Transcription Factor CBF3 Promoter in Response to Abiotic Stress.
    Int J Mol Sci, 2015. 16(6): p. 12131-46
    [PMID:26030672]
  13. Challam C,Ghosh T,Rai M,Tyagi W
    Allele mining across DREB1A and DREB1B in diverse rice genotypes suggest a highly conserved pathway inducible by low temperature.
    J. Genet., 2015. 94(2): p. 231-8
    [PMID:26174670]
  14. Kan CC,Chung TY,Juo YA,Hsieh MH
    Glutamine rapidly induces the expression of key transcription factor genes involved in nitrogen and stress responses in rice roots.
    BMC Genomics, 2015. 16(1): p. 731
    [PMID:26407850]
  15. Min HJ,Jung YJ,Kang BG,Kim WT
    CaPUB1, a Hot Pepper U-box E3 Ubiquitin Ligase, Confers Enhanced Cold Stress Tolerance and Decreased Drought Stress Tolerance in Transgenic Rice (Oryza sativa L.).
    Mol. Cells, 2016. 39(3): p. 250-7
    [PMID:26674966]
  16. Kakar KU, et al.
    A consortium of rhizobacterial strains and biochemical growth elicitors improve cold and drought stress tolerance in rice (Oryza sativa L.).
    Plant Biol (Stuttg), 2016. 18(3): p. 471-83
    [PMID:26681628]
  17. Huo C, et al.
    Comparative Study of Early Cold-Regulated Proteins by Two-Dimensional Difference Gel Electrophoresis Reveals a Key Role for Phospholipase Dα1 in Mediating Cold Acclimation Signaling Pathway in Rice.
    Mol. Cell Proteomics, 2016. 15(4): p. 1397-411
    [PMID:26747563]
  18. Dou M,Cheng S,Zhao B,Xuan Y,Shao M
    The Indeterminate Domain Protein ROC1 Regulates Chilling Tolerance via Activation of DREB1B/CBF1 in Rice.
    Int J Mol Sci, 2016. 17(3): p. 233
    [PMID:26927068]
  19. Kudo M, et al.
    Double overexpression of DREB and PIF transcription factors improves drought stress tolerance and cell elongation in transgenic plants.
    Plant Biotechnol. J., 2017. 15(4): p. 458-471
    [PMID:27683092]
  20. He X, et al.
    A rice jacalin-related mannose-binding lectin gene, OsJRL, enhances Escherichia coli viability under high salinity stress and improves salinity tolerance of rice.
    Plant Biol (Stuttg), 2017. 19(2): p. 257-267
    [PMID:27718311]