PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID EPS64094.1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Lentibulariaceae; Genlisea
Family ARF
Protein Properties Length: 892aa    MW: 98463 Da    PI: 6.6728
Description ARF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
EPS64094.1genomeLSMUView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1B373.91.9e-23127228199
                 EEEE-..-HHHHTT-EE--HHH.HTT.......---..--SEEEEEETTS-EEEEEE..EEETTEEEE-TTHHHHHHHHT--TT-EEEEEE-SSSEE.. CS
          B3   1 ffkvltpsdvlksgrlvlpkkfaeeh.......ggkkeesktltledesgrsWevkliyrkksgryvltkGWkeFvkangLkegDfvvFkldgrsefel 92 
                 f+k+lt sd++++g +++p++ ae++       + +++  ++l+++d++ ++W++++iyr++++r++lt+GW+ Fv++++L +gD v+F +  +++ +l
  EPS64094.1 127 FCKTLTASDTSTHGGFSVPRRAAEKIfppldfsM-QPPA-QELSVKDLHDQTWTFRHIYRGQPKRHLLTTGWSVFVSSKRLVAGDGVLFVR--DERSRL 221
                 99*****************************954.4444.49************************************************4..466667 PP

                 EEEEE-S CS
          B3  93 vvkvfrk 99 
                 +++++r+
  EPS64094.1 222 LLGIRRA 228
                 9999997 PP

2Auxin_resp117.51.1e-38253335183
  Auxin_resp   1 aahaastksvFevvYnPrastseFvvkvekvekalkvkvsvGmRfkmafetedsserrlsGtvvgvsdldpvrWpnSkWrsLk 83 
                 aahaa+++s+F+++YnPr+++s+Fv++++k++kal+++vs+GmRf+m+fe+e+s  rr++Gtv+g+sdldp+rW++S+Wr+L+
  EPS64094.1 253 AAHAAANNSPFTIFYNPRSCRSDFVIPLAKYNKALYTQVSPGMRFRMMFESEESGLRRYMGTVTGISDLDPTRWKGSQWRNLQ 335
                 79*******************************************************************************97 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF1019362.62E-43115256IPR015300DNA-binding pseudobarrel domain
Gene3DG3DSA:2.40.330.101.0E-40119242IPR015300DNA-binding pseudobarrel domain
CDDcd100171.29E-21126227No hitNo description
SMARTSM010192.1E-22127229IPR003340B3 DNA binding domain
PROSITE profilePS5086312.661127229IPR003340B3 DNA binding domain
PfamPF023623.3E-21127228IPR003340B3 DNA binding domain
PfamPF065072.3E-33253335IPR010525Auxin response factor
PfamPF023092.7E-10759847IPR033389AUX/IAA domain
PROSITE profilePS5174524.637761854IPR000270PB1 domain
SuperFamilySSF542772.55E-8764839No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009723Biological Processresponse to ethylene
GO:0009734Biological Processauxin-activated signaling pathway
GO:0010311Biological Processlateral root formation
GO:0048366Biological Processleaf development
GO:0005634Cellular Componentnucleus
GO:0043565Molecular Functionsequence-specific DNA binding
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 892 aa     Download sequence    Send to blast
MKIASTIATS SHSAEGGKKL INSELWHACA GPLVSLPNAG SLVVYFPQGH SEQVASSMQK  60
EADGIPSYPN LPSKLICMLH NVTLHADAET DEVYAQMTLQ PVGKYDQEAL IVSDIGLKHS  120
KQPTEFFCKT LTASDTSTHG GFSVPRRAAE KIFPPLDFSM QPPAQELSVK DLHDQTWTFR  180
HIYRGQPKRH LLTTGWSVFV SSKRLVAGDG VLFVRDERSR LLLGIRRANQ NQPVLSSSII  240
SSDSMHIGIL VAAAHAAANN SPFTIFYNPR SCRSDFVIPL AKYNKALYTQ VSPGMRFRMM  300
FESEESGLRR YMGTVTGISD LDPTRWKGSQ WRNLQVGWDE SNAGERPSRV SIWDIEPVIS  360
PFYICPPPFF RPRNPYFPDG DMDMECMLMR QGMMPLMGND LSFKDGSIFP GLNLVQRMSM  420
QNQLSSSANQ YGLVSSPIMQ TSSNFQANLQ QQGSLHPQQS PLLLTSSGGR MTCDHLATNQ  480
GLLQPSAVCS CRVQQQLPME QSELQQHCRK NGPHGAAAIE NLPFAAAQEG SLQLIHQEAK  540
SKTRSQQRMQ MQMPLVQKKV QMKGSSSLNP VMDFQQMNGI SFSPAASLQQ DAPVIPEDAP  600
SCSSMSHSRS NILLPQRILN FKNHADSSSQ LVRESSSHGN PDVGMKHELS SNSKAADIHL  660
DVTSPSPASC YLYAAANPLT ATDADDALLS RGYDSGKNLQ DLLFNYSDIP TPPTDMSSGI  720
QSQSFSVPNI SAKTVYMNDA DVNDVVVPNG GRWSNQTPRM RTYTKVQKRG SVGRTIDVNR  780
YKGYEELKQD LARMFAIEGL LGDQQRSEWK LVYVDHENDI LLVGDDPWEE FVGCVQSIKI  840
LSSAEVQQMS LDGGDHPAAG QQLNQACNNS ADGEATMIPW RGNYENNSAF DH
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4ldu_A1e-1701835648388Auxin response factor 5
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtAuxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs). Could act as transcriptional activator or repressor. Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression. Involved in ethylene responses. Regulates lateral root formation through direct regulation of LBD16 and/or LBD29. Functionally redundant with ARF7. {ECO:0000269|PubMed:12036261, ECO:0000269|PubMed:16461383, ECO:0000269|PubMed:17259263}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By auxin and ethylene. {ECO:0000269|PubMed:16461383}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_012851206.10.0PREDICTED: auxin response factor 19-like
SwissprotQ8RYC80.0ARFS_ARATH; Auxin response factor 19
TrEMBLS8CAY50.0S8CAY5_9LAMI; Auxin response factor
STRINGMigut.J00900.1.p0.0(Erythranthe guttata)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA13022465
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G19220.10.0auxin response factor 19
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Leushkin EV, et al.
    The miniature genome of a carnivorous plant Genlisea aurea contains a low number of genes and short non-coding sequences.
    BMC Genomics, 2013. 14: p. 476
    [PMID:23855885]
  3. Perilli S, et al.
    RETINOBLASTOMA-RELATED protein stimulates cell differentiation in the Arabidopsis root meristem by interacting with cytokinin signaling.
    Plant Cell, 2013. 25(11): p. 4469-78
    [PMID:24285791]
  4. Sun Y, et al.
    Manipulation of Auxin Response Factor 19 affects seed size in the woody perennial Jatropha curcas.
    Sci Rep, 2017. 7: p. 40844
    [PMID:28102350]
  5. Wójcikowska B,Gaj MD
    Expression profiling of AUXIN RESPONSE FACTOR genes during somatic embryogenesis induction in Arabidopsis.
    Plant Cell Rep., 2017. 36(6): p. 843-858
    [PMID:28255787]
  6. Olmo R, et al.
    Molecular Transducers from Roots Are Triggered in Arabidopsis Leaves by Root-Knot Nematodes for Successful Feeding Site Formation: A Conserved Post-Embryogenic De novo Organogenesis Program?
    Front Plant Sci, 2017. 8: p. 875
    [PMID:28603536]
  7. Lee K,Seo PJ
    High-temperature promotion of callus formation requires the BIN2-ARF-LBD axis in Arabidopsis.
    Planta, 2017. 246(4): p. 797-802
    [PMID:28766014]
  8. Ayala-Rodríguez JÁ,Barrera-Ortiz S,Ruiz-Herrera LF,López-Bucio J
    Folic acid orchestrates root development linking cell elongation with auxin response and acts independently of the TARGET OF RAPAMYCIN signaling in Arabidopsis thaliana.
    Plant Sci., 2017. 264: p. 168-178
    [PMID:28969797]
  9. Nakamura M, et al.
    Auxin and ROP GTPase Signaling of Polar Nuclear Migration in Root Epidermal Hair Cells.
    Plant Physiol., 2018. 176(1): p. 378-391
    [PMID:29084900]
  10. Hong L, et al.
    Alternative polyadenylation is involved in auxin-based plant growth and development.
    Plant J., 2018. 93(2): p. 246-258
    [PMID:29155478]
  11. Lee K,Park OS,Seo PJ
    Arabidopsis ATXR2 deposits H3K36me3 at the promoters of LBD genes to facilitate cellular dedifferentiation.
    Sci Signal, 2018.
    [PMID:29184030]
  12. Kimura T, et al.
    Asymmetric Auxin Distribution is Not Required to Establish Root Phototropism in Arabidopsis.
    Plant Cell Physiol., 2018. 59(4): p. 823-835
    [PMID:29401292]
  13. Schoenaers S, et al.
    The Auxin-Regulated CrRLK1L Kinase ERULUS Controls Cell Wall Composition during Root Hair Tip Growth.
    Curr. Biol., 2018. 28(5): p. 722-732.e6
    [PMID:29478854]
  14. Huang KL, et al.
    The ARF7 and ARF19 Transcription Factors Positively Regulate PHOSPHATE STARVATION RESPONSE1 in Arabidopsis Roots.
    Plant Physiol., 2018. 178(1): p. 413-427
    [PMID:30026290]