PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Capsella

Family

MYB

Protein Properties

Length: 267aa MW: 30849.7 Da PI: 6.4368

Description

MYB family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Cagra.3166s0041.1.p	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Myb_DNA-binding	40.8	5.2e-13	14	61	1	48
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 rg+WT eEd +l + + G ++W+ +++ g+ R++k+c++rw +yl Cagra.3166s0041.1.p 14 RGPWTIEEDHRLMNFILNNGIHCWRIVPKLAGLLRCGKSCRLRWINYL 61 89****************************99**********97 PP
2	Myb_DNA-binding	51.9	1.7e-16	67	110	1	46
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHH CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqk 46 rg +T E++++ +++ qlG++ W++Ia+++ gRt++++k++w++ Cagra.3166s0041.1.p 67 RGGFTDAEEDRIMELHSQLGNR-WSKIASHFS-GRTDNEIKNHWNT 110 788*****************.*****.*********96 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.10.60	5.1E-20	5	64	IPR009057	Homeodomain-like
PROSITE profile	PS51294	13.605	9	61	IPR017930	Myb domain
SuperFamily	SSF46689	1.65E-27	11	108	IPR009057	Homeodomain-like
SMART	SM00717	1.1E-5	13	63	IPR001005	SANT/Myb domain
Pfam	PF00249	3.2E-11	14	61	IPR001005	SANT/Myb domain
CDD	cd00167	0.001	16	61	No hit	No description
PROSITE profile	PS51294	25.127	62	116	IPR017930	Myb domain
Gene3D	G3DSA:1.10.10.60	4.2E-25	65	117	IPR009057	Homeodomain-like
SMART	SM00717	5.6E-14	66	114	IPR001005	SANT/Myb domain
Pfam	PF00249	4.5E-14	67	110	IPR001005	SANT/Myb domain
CDD	cd00167	8.33E-9	70	110	No hit	No description
Gene3D	G3DSA:3.40.50.300	4.3E-4	157	223	IPR027417	P-loop containing nucleoside triphosphate hydrolase

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 267 aa Download sequence Send to blast
MGRKPCCEKI GLKRGPWTIE EDHRLMNFIL NNGIHCWRIV PKLAGLLRCG KSCRLRWINY 60 LRPDLKRGGF TDAEEDRIME LHSQLGNRWS KIASHFSGRT DNEIKNHWNT KIKKKMKHLG 120 LDPATHKPMN NITHQTDPNH QDTKPKMCSS INNEGEEMKD QTPKDDVIKE TTKALTDNNE 180 ELVEKNWKNQ RAEEVDLESL FETQGNEISS NSSISSLYSN ISRNESSSYL AEDSISLEQW 240 DLDMTDPFVP WDLFAANLDH DHLFFL*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1a5j_A	3e-26	12	116	5	108	B-MYB
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that acts as positive regulator of abscisic acid (ABA) signaling in response to salt stress. Acts as negative regulator ABI1, ABI2 and PP2CA, which are protein phosphatases 2C acting as negative regulator of ABA signaling. Binds to the DNA specific sequence and core element 5'-ACGT-3' found in the promoters of ABI1 and PP2CA to negatively regulate their expression during ABA-dependent salt stress response. {ECO:0000269\|PubMed:23660402}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00510	DAP	Transfer from AT5G14340	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Cagra.3166s0041.1.p

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by salt stress, drought stress and abscisic acid (ABA). Down-regulated by salicylic acid (SA) methyl jasmonate (JA). {ECO:0000269\|PubMed:23660402}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AY519622	0.0	AY519622.1 Arabidopsis thaliana MYB transcription factor (At5g14340) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006289133.1	0.0	transcription factor MYB20
Swissprot	Q9C7U7	2e-70	MYB20_ARATH; Transcription factor MYB20
TrEMBL	R0FJ11	0.0	R0FJ11_9BRAS; Uncharacterized protein
STRING	Cagra.3166s0041.1.p	0.0	(Capsella grandiflora)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM4	28	2646

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G14340.1	1e-152	myb domain protein 40

Link Out ? help Back to Top
Phytozome	Cagra.3166s0041.1.p

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546]