PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Araip.E51AM
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Dalbergieae; Arachis
Family ARF
Protein Properties Length: 911aa    MW: 100571 Da    PI: 5.3594
Description ARF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Araip.E51AMgenomeNCGR_PGCView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1B334.83e-11158239199
                  EEEE-..-HHHHTT-EE--HHH.HTT..---..--SEEEEEETTS-EEEEEE..EEETTEEEE-TTHHHHHHHHT--TT-EEEEEE-SSSEE..EEEE CS
           B3   1 ffkvltpsdvlksgrlvlpkkfaeeh..ggkkeesktltledesgrsWevkliyrkksgryvltkGWkeFvkangLkegDfvvFkldgrsefelvvkv 96 
                  f+k+lt sd++++g +++p++ ae+    +++++              e+ +   ++++r++lt+GW+ Fv +++L++gD+v+F   ++++ +l+v+v
  Araip.E51AM 158 FCKTLTASDTSTHGGFSVPRRAAEKLfpPLPPTQ--------------ELVV---RQPKRHLLTTGWSLFVGSKRLRAGDSVLFI--RDEKSQLRVGV 236
                  8999999999999999999999999966555544..............3445...77899*************************..4577778**** PP

                  E-S CS
           B3  97 frk 99 
                  +r 
  Araip.E51AM 237 RRV 239
                  985 PP

2Auxin_resp113.91.5e-37264347183
   Auxin_resp   1 aahaastksvFevvYnPrastseFvvkvekvekalk.vkvsvGmRfkmafetedsserrlsGtvvgvsdldpvrWpnSkWrsLk 83 
                  aahaas++ +F+++YnPra++seFv++++k++k+++ +++svGmRf m+fete+s +rr++Gt+vg+sdldp+rWp+SkWr+++
  Araip.E51AM 264 AAHAASNRIPFTIFYNPRACPSEFVIPLAKYRKSVYgTQLSVGMRFGMMFETEESGKRRYMGTIVGISDLDPLRWPGSKWRNIQ 347
                  79**********************************9********************************************986 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF1019368.5E-33146267IPR015300DNA-binding pseudobarrel domain
Gene3DG3DSA:2.40.330.109.7E-24151252IPR015300DNA-binding pseudobarrel domain
CDDcd100174.48E-14157238No hitNo description
SMARTSM010196.8E-11158240IPR003340B3 DNA binding domain
PfamPF023629.0E-9158239IPR003340B3 DNA binding domain
PROSITE profilePS508638.783200240IPR003340B3 DNA binding domain
PfamPF065072.9E-32264347IPR010525Auxin response factor
PfamPF023097.0E-11802892IPR033389AUX/IAA domain
PROSITE profilePS5174523.746805889IPR000270PB1 domain
SuperFamilySSF542775.1E-8809884No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009733Biological Processresponse to auxin
GO:0009908Biological Processflower development
GO:0009942Biological Processlongitudinal axis specification
GO:0010305Biological Processleaf vascular tissue pattern formation
GO:0048364Biological Processroot development
GO:0048507Biological Processmeristem development
GO:0005634Cellular Componentnucleus
GO:0016020Cellular Componentmembrane
GO:0042802Molecular Functionidentical protein binding
GO:0044212Molecular Functiontranscription regulatory region DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 911 aa     Download sequence    Send to blast
MFKNVESGAA LMASLEEKVK TCGVGVVGGQ TLVAEMKLLK EMQEHSGVRK TLNSELWHAC  60
AGPLVSLPQV GSLVYYFPQG HSEQVAASTR RTATSQIPNY PNLPSQLLCQ VQNVTLHADK  120
DTDEIYAQMS LQPLNSEKDV FPISDFGLKH SKHPTEFFCK TLTASDTSTH GGFSVPRRAA  180
EKLFPPLPPT QELVVRQPKR HLLTTGWSLF VGSKRLRAGD SVLFIRDEKS QLRVGVRRVN  240
RQQTTLPSSV LSADSMHIGV LAAAAHAASN RIPFTIFYNP RACPSEFVIP LAKYRKSVYG  300
TQLSVGMRFG MMFETEESGK RRYMGTIVGI SDLDPLRWPG SKWRNIQVEW DEPGCGDKQN  360
RVSVWEIETP ESLFIFPSLT SSLKRPLQSG FLENDWGALI RRPYIRVPEN GATELANSMP  420
NIYSEHLMKM LLKPQLINNN GAMAMQQESV AMRGTLQDAK TTQAPENHKV NLASTENLPL  480
KNLYSQSVPD QANVVNLHSQ AKNDNHMSSG TVIDKPKLEP EVLNDQMYEI PSAGTGTNIE  540
KVASNPANSQ SVANQLAFLN QNQSQSLAQS GSWPIQPQLE SSVSHPQLVD MPQGDSAIAN  600
SMLPQLDIDE WMVYSSNQTF ANQNRSTGPV SDFQEHSAAL QPQVVNPPMP MNQEVWDQYV  660
KNFKLLSQVD QLTSVCQPGM YSLNGISSSN NLRDLSAESN NQSEICVDVS NSVNTTMVDP  720
STSSTILDEY CTLKERDFQN PQDCIVGNLS SSQDVQSQIT SASLTESHAF PLQDNSGGTS  780
SSHVDFDESS FLQNNSWQPV AAPVRTYTKV QKAGSVGRSI DVTTFKNYEE LIRAIECMFG  840
LDGLLNDTKG SGWKLVYVDY ESDVLLVGDD PWEEFVGCVR CIRILSPSEV QQMSEEGMKL  900
LNSGALQGIN V
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4ldu_A0.0113721392Auxin response factor 5
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtAuxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs). Seems to act as transcriptional activator. Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression. Mediates embryo axis formation and vascular tissues differentiation. Functionally redundant with ARF7. May be necessary to counteract AMP1 activity. {ECO:0000269|PubMed:12036261, ECO:0000269|PubMed:14973283, ECO:0000269|PubMed:17553903}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00153DAPTransfer from AT1G19850Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapAraip.E51AM
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_025657714.10.0auxin response factor 5 isoform X1
SwissprotP930240.0ARFE_ARATH; Auxin response factor 5
TrEMBLA0A444YGE90.0A0A444YGE9_ARAHY; Auxin response factor
STRINGGLYMA14G40540.10.0(Glycine max)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF89913241
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G19850.10.0ARF family protein
Publications ? help Back to Top
  1. Chen MK,Wilson RL,Palme K,Ditengou FA,Shpak ED
    ERECTA family genes regulate auxin transport in the shoot apical meristem and forming leaf primordia.
    Plant Physiol., 2013. 162(4): p. 1978-91
    [PMID:23821653]
  2. Huang JB, et al.
    ROP3 GTPase contributes to polar auxin transport and auxin responses and is important for embryogenesis and seedling growth in Arabidopsis.
    Plant Cell, 2014. 26(9): p. 3501-18
    [PMID:25217509]
  3. Qi J, et al.
    Auxin depletion from leaf primordia contributes to organ patterning.
    Proc. Natl. Acad. Sci. U.S.A., 2014. 111(52): p. 18769-74
    [PMID:25512543]
  4. Crawford BC, et al.
    Plant development. Genetic control of distal stem cell fate within root and embryonic meristems.
    Science, 2015. 347(6222): p. 655-9
    [PMID:25612610]
  5. Zhang Y, et al.
    Regulation of oncogene expression in T-DNA-transformed host plant cells.
    PLoS Pathog., 2015. 11(1): p. e1004620
    [PMID:25615824]
  6. Robert HS, et al.
    Plant embryogenesis requires AUX/LAX-mediated auxin influx.
    Development, 2015. 142(4): p. 702-11
    [PMID:25617434]
  7. Krogan NT,Berleth T
    The identification and characterization of specific ARF-Aux/IAA regulatory modules in plant growth and development.
    Plant Signal Behav, 2015. 10(4): p. e992748
    [PMID:25830553]
  8. Ckurshumova W,Berleth T
    Overcoming recalcitrance - Auxin response factor functions in plant regeneration.
    Plant Signal Behav, 2015. 10(7): p. e993293
    [PMID:26098229]
  9. Wendrich JR, et al.
    A set of domain-specific markers in the Arabidopsis embryo.
    Plant Reprod, 2015. 28(3-4): p. 153-60
    [PMID:26216537]
  10. Wu MF, et al.
    Auxin-regulated chromatin switch directs acquisition of flower primordium founder fate.
    Elife, 2015. 4: p. e09269
    [PMID:26460543]
  11. Yamaguchi N,Jeong CW,Nole-Wilson S,Krizek BA,Wagner D
    AINTEGUMENTA and AINTEGUMENTA-LIKE6/PLETHORA3 Induce LEAFY Expression in Response to Auxin to Promote the Onset of Flower Formation in Arabidopsis.
    Plant Physiol., 2016. 170(1): p. 283-93
    [PMID:26537561]
  12. Müller CJ, et al.
    PHABULOSA Mediates an Auxin Signaling Loop to Regulate Vascular Patterning in Arabidopsis.
    Plant Physiol., 2016. 170(2): p. 956-70
    [PMID:26637548]
  13. Herud O,Weijers D,Lau S,Jürgens G
    Auxin responsiveness of the MONOPTEROS-BODENLOS module in primary root initiation critically depends on the nuclear import kinetics of the Aux/IAA inhibitor BODENLOS.
    Plant J., 2016. 85(2): p. 269-77
    [PMID:26714008]
  14. Luo S, et al.
    Constitutive Expression of OsIAA9 Affects Starch Granules Accumulation and Root Gravitropic Response in Arabidopsis.
    Front Plant Sci, 2015. 6: p. 1156
    [PMID:26734051]
  15. Yamaguchi N,Wu MF,Winter CM,Wagner D
    LEAFY and Polar Auxin Transport Coordinately Regulate Arabidopsis Flower Development.
    Plants (Basel), 2014. 3(2): p. 251-65
    [PMID:27135503]
  16. Krogan NT,Marcos D,Weiner AI,Berleth T
    The auxin response factor MONOPTEROS controls meristem function and organogenesis in both the shoot and root through the direct regulation of PIN genes.
    New Phytol., 2016. 212(1): p. 42-50
    [PMID:27441727]
  17. Fendrych M,Leung J,Friml J
    TIR1/AFB-Aux/IAA auxin perception mediates rapid cell wall acidification and growth of Arabidopsis hypocotyls.
    Elife, 2018.
    [PMID:27627746]
  18. Matthes M,Torres-Ruiz RA
    Boronic acid treatment phenocopies monopteros by affecting PIN1 membrane stability and polar auxin transport in Arabidopsis thaliana embryos.
    Development, 2016. 143(21): p. 4053-4062
    [PMID:27697905]
  19. Bhatia N, et al.
    Auxin Acts through MONOPTEROS to Regulate Plant Cell Polarity and Pattern Phyllotaxis.
    Curr. Biol., 2016. 26(23): p. 3202-3208
    [PMID:27818174]
  20. Wójcikowska B,Gaj MD
    Expression profiling of AUXIN RESPONSE FACTOR genes during somatic embryogenesis induction in Arabidopsis.
    Plant Cell Rep., 2017. 36(6): p. 843-858
    [PMID:28255787]
  21. Möller BK, et al.
    Auxin response cell-autonomously controls ground tissue initiation in the early Arabidopsis embryo.
    Proc. Natl. Acad. Sci. U.S.A., 2017. 114(12): p. E2533-E2539
    [PMID:28265057]
  22. Carey NS,Krogan NT
    The role of AUXIN RESPONSE FACTORs in the development and differential growth of inflorescence stems.
    Plant Signal Behav, 2017. 12(4): p. e1307492
    [PMID:28340328]
  23. Guan C, et al.
    Spatial Auxin Signaling Controls Leaf Flattening in Arabidopsis.
    Curr. Biol., 2017. 27(19): p. 2940-2950.e4
    [PMID:28943086]
  24. Gaillochet C, et al.
    Control of plant cell fate transitions by transcriptional and hormonal signals.
    Elife, 2018.
    [PMID:29058667]
  25. Zheng K, et al.
    Involvement of PACLOBUTRAZOL RESISTANCE6/KIDARI, an Atypical bHLH Transcription Factor, in Auxin Responses in Arabidopsis.
    Front Plant Sci, 2017. 8: p. 1813
    [PMID:29114256]
  26. Liu Z, et al.
    ARF2-ARF4 and ARF5 are Essential for Female and Male Gametophyte Development in Arabidopsis.
    Plant Cell Physiol., 2018. 59(1): p. 179-189
    [PMID:29145642]