PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Achn231301

Organism

Actinidia chinensis

Taxonomic ID

3625

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; Ericales; Actinidiaceae; Actinidia

Family

C2H2

Protein Properties

Length: 356aa MW: 39833.5 Da PI: 5.0475

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Achn231301	genome	IKGC	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	12.4	0.00048	139	161	3	23
ET..TTTEEESSHHHHHHHHHHT CS zf-C2H2 3 Cp..dCgksFsrksnLkrHirtH 23 C+ Cgk+F + L++H H Achn231301 139 CSyeGCGKTFIDAGALRKHSHIH 161 77779**************7766 PP
2	zf-C2H2	11.1	0.0013	211	236	1	23
EEET..TTTEEESSHHHHHHHHHH.T CS zf-C2H2 1 ykCp..dCgksFsrksnLkrHirt.H 23 y Cp C k + + + L+ H+r+ H Achn231301 211 YCCPyeGCEKAYIHEYKLNLHLRReH 236 7899*******************999 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:3.30.160.60	8.9E-14	132	163	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamily	SSF57667	1.18E-6	132	173	No hit	No description
SMART	SM00355	0.0032	137	161	IPR015880	Zinc finger, C2H2-like
PROSITE profile	PS50157	10.783	137	166	IPR007087	Zinc finger, C2H2
PROSITE pattern	PS00028	0	139	161	IPR007087	Zinc finger, C2H2
Gene3D	G3DSA:3.30.160.60	2.9E-4	164	176	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamily	SSF57667	2.12E-5	206	234	No hit	No description
Gene3D	G3DSA:3.30.160.60	6.1E-8	206	234	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SMART	SM00355	0.044	211	236	IPR015880	Zinc finger, C2H2-like
PROSITE profile	PS50157	8.954	211	241	IPR007087	Zinc finger, C2H2
PROSITE pattern	PS00028	0	213	236	IPR007087	Zinc finger, C2H2

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003676	Molecular Function	nucleic acid binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 356 aa Download sequence Send to blast
MQQSWEEVVT RTCAFLKSGS DTDTLSRLSV STTPKARTFL GCVEFEVKPC TILSINTFQL 60 TSNCNDLIWL ILKSMHKVGL ACVRLGRVGL PQDVVATGGK CILFRWVPEA TLKAMKEKSK 120 EPEAVEPEPE PTTEVLFLCS YEGCGKTFID AGALRKHSHI HGERQYVCHY DGCGKNNVDI 180 TPKYVQPPEK LPKTSKPSSA AYGSASSDRP YCCPYEGCEK AYIHEYKLNL HLRREHPGHL 240 GDDNAKNSQS AIDNDMDEGS DQDVYAGKRG SSKIQKQSKP KQNLKMPPAK VARKGSSASP 300 ANLYVMKKPW PVKEEIYEDD EEDSEETEED RDNVEDGWRH GENNEDDDEE TEYED*

Sequence ? help Back to Top

Protein Sequence Length: 356 aa Download sequence Send to blast

MQQSWEEVVT RTCAFLKSGS DTDTLSRLSV STTPKARTFL GCVEFEVKPC TILSINTFQL  60
TSNCNDLIWL ILKSMHKVGL ACVRLGRVGL PQDVVATGGK CILFRWVPEA TLKAMKEKSK  120
EPEAVEPEPE PTTEVLFLCS YEGCGKTFID AGALRKHSHI HGERQYVCHY DGCGKNNVDI  180
TPKYVQPPEK LPKTSKPSSA AYGSASSDRP YCCPYEGCEK AYIHEYKLNL HLRREHPGHL  240
GDDNAKNSQS AIDNDMDEGS DQDVYAGKRG SSKIQKQSKP KQNLKMPPAK VARKGSSASP  300
ANLYVMKKPW PVKEEIYEDD EEDSEETEED RDNVEDGWRH GENNEDDDEE TEYED*

Functional Description ? help Back to Top
Source	Description
UniProt	Dual-function transcription factor with both repression and activation activities. Binds to 5'-CCATATT-3' motif in target gene promoters (e.g. ABR1) (PubMed:26961720). Binds also to G-rich DNA motif 5'-GGGGGCAGTGG-3' (PubMed:22508367). Regulates the expression of genes involved in diverse cellular pathways, including glucose metabolism, photosynthesis, phototropism and stress response (e.g. salt, drought and osmotic stress) (PubMed:22508367, PubMed:26961720). Regulates plant immunity, especially during necrotrophic fungal infection (e.g. B.cinerea) (PubMed:24451981). Binds to ABR1 promoter and promotes its expression, thus negatively regulating the abscisic acid (ABA) signaling pathway. Represses ABA- and salt-responsive genes expression (PubMed:26961720). {ECO:0000269\|PubMed:22508367, ECO:0000269\|PubMed:24451981, ECO:0000269\|PubMed:26961720}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by abscisic acid (ABA) in an ABI1- and ABI4-dependent manner. Stimulated by stress conditions including high salt, osmotic stress (e.g. mannitol) and dehydration. May be induced by ABI4 but repressed by ABR1. Repressed by darkness but induced by light. {ECO:0000269\|PubMed:26961720}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_028086098.1	1e-108	zinc finger transcription factor YY1
Swissprot	Q2V3L3	1e-71	YY1_ARATH; Zinc finger transcription factor YY1
TrEMBL	A0A2R6Q6J4	1e-131	A0A2R6Q6J4_ACTCH; Zinc finger, C2H2 protein
STRING	XP_008218753.1	2e-93	(Prunus mume)
STRING	EMJ24499	2e-93	(Prunus persica)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA7343	23	32

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G06634.1	1e-65	C2H2 family protein

Publications ? help Back to Top
Kumekawa N,Hosouchi T,Tsuruoka H,Kotani H The size and sequence organization of the centromeric region of Arabidopsis thaliana chromosome 4. DNA Res., 2001. 8(6): p. 285-90 [PMID:11853315] Li T,Wu XY,Li H,Song JH,Liu JY A Dual-Function Transcription Factor, AtYY1, Is a Novel Negative Regulator of the Arabidopsis ABA Response Network. Mol Plant, 2016. 9(5): p. 650-661 [PMID:26961720] Wu XY,Li T A Casein Kinase II Phosphorylation Site in AtYY1 Affects Its Activity, Stability, and Function in the ABA Response. Front Plant Sci, 2017. 8: p. 323 [PMID:28348572]