PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

676745238

Organism

Sisymbrium irio

Taxonomic ID

3730

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Sisymbrieae; Sisymbrium

Family

GRF

Protein Properties

Length: 544aa MW: 59128.6 Da PI: 9.4205

Description

GRF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
676745238	genome	VEGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	WRC	78.5	6.6e-25	233	276	1	44
WRC 1 daepgrCrRtDGKkWRCsrrvlegkklCErHlhrgrsrsrkske 44 d+epgrCrRtDGKkWRCsr++++++k+CErH++rgr+rsrk++e 676745238 233 DPEPGRCRRTDGKKWRCSRDAVPDQKYCERHINRGRHRSRKPVE 276 79***************************************998 PP
2	QLQ	54.3	4.2e-19	169	205	1	37
QLQ 1 saFTaaQlqlLksQilAyKyLaanqPvPpeLlqaiqk 37 ++FT +Q+++L++Q+l+yKy+ an+PvP+ Ll iqk 676745238 169 GPFTLTQWAELEQQALIYKYITANVPVPSSLLISIQK 205 59*********************************97 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM00951	4.1E-12	169	205	IPR014978	Glutamine-Leucine-Glutamine, QLQ
PROSITE profile	PS51666	21.884	170	205	IPR014978	Glutamine-Leucine-Glutamine, QLQ
Pfam	PF08880	4.7E-13	170	204	IPR014978	Glutamine-Leucine-Glutamine, QLQ
PROSITE profile	PS51667	25.77	233	277	IPR014977	WRC domain
Pfam	PF08879	3.5E-21	234	276	IPR014977	WRC domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0008285	Biological Process	negative regulation of cell proliferation
GO:0048364	Biological Process	root development
GO:0048366	Biological Process	leaf development
GO:0005634	Cellular Component	nucleus
GO:0005524	Molecular Function	ATP binding

Sequence ? help Back to Top
Protein Sequence Length: 544 aa Download sequence Send to blast
MDIGTHILGS VTGNANGSPG LKELGGSKQD RSGFDGEDCL QQSSKLARTT TTTTTTTIAQ 60 DKHLSSSYAA AYSKPMSFHQ GIPLMRSASL LSSDSRRQEH MLSFSDKPEA LDFSKYVGVD 120 NSINNKNSLS PFFHQQLPPP YCRSSGGGYG SGGMMMNMSM QGNFTGVKGP FTLTQWAELE 180 QQALIYKYIT ANVPVPSSLL ISIQKSFYPY GSLPPSSFGW GAFHLGLAGG NMDPEPGRCR 240 RTDGKKWRCS RDAVPDQKYC ERHINRGRHR SRKPVEVQSG QTAAAAASKS VTTPQQSMVA 300 GGNIRNNARA SRNRSLASAA QYINPSTTSL PNNRIQDPVG SSVYPSTVNL QPKEPPFPHQ 360 KQRNINISST FEFGHISSDS LLNPNSAKSY ASSYLDFTNN QDKPSGNHNP NSWPEELKSD 420 WTQLSMSIPI ASSSPSSTQN TAQDKTTLSP LRLSREFDHS IQSEQETLEP VKKVNTWIPI 480 SWGNSLGGPL GEVLNSTTNS PTLGSSPTGV LQKTTFCSLS NSSSVSSPIA ENNRNNVDYF 540 HYTT

Sequence ? help Back to Top

Protein Sequence Length: 544 aa Download sequence Send to blast

MDIGTHILGS VTGNANGSPG LKELGGSKQD RSGFDGEDCL QQSSKLARTT TTTTTTTIAQ  60
DKHLSSSYAA AYSKPMSFHQ GIPLMRSASL LSSDSRRQEH MLSFSDKPEA LDFSKYVGVD  120
NSINNKNSLS PFFHQQLPPP YCRSSGGGYG SGGMMMNMSM QGNFTGVKGP FTLTQWAELE  180
QQALIYKYIT ANVPVPSSLL ISIQKSFYPY GSLPPSSFGW GAFHLGLAGG NMDPEPGRCR  240
RTDGKKWRCS RDAVPDQKYC ERHINRGRHR SRKPVEVQSG QTAAAAASKS VTTPQQSMVA  300
GGNIRNNARA SRNRSLASAA QYINPSTTSL PNNRIQDPVG SSVYPSTVNL QPKEPPFPHQ  360
KQRNINISST FEFGHISSDS LLNPNSAKSY ASSYLDFTNN QDKPSGNHNP NSWPEELKSD  420
WTQLSMSIPI ASSSPSSTQN TAQDKTTLSP LRLSREFDHS IQSEQETLEP VKKVNTWIPI  480
SWGNSLGGPL GEVLNSTTNS PTLGSSPTGV LQKTTFCSLS NSSSVSSPIA ENNRNNVDYF  540
HYTT

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that plays a role in the regulation of cell expansion in leaf and cotyledons tissues. Component of a network formed by miR396, the GRFs and their interacting factors (GIFs) acting in the regulation of meristem function, at least partially through the control of cell proliferation. {ECO:0000269\|PubMed:12974814, ECO:0000269\|PubMed:15326298, ECO:0000269\|PubMed:20023165, ECO:0000269\|PubMed:21036927}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	676745238

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: microRNA 396 (miR396a or miR396b) negatively regulates growth-regulating factors (GRF1-4 and GRF7-9). {ECO:0000269\|PubMed:15200956, ECO:0000269\|PubMed:19453503, ECO:0000269\|PubMed:20023165}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	NP_195488.2	0.0	growth-regulating factor 2
Swissprot	Q8L8A8	0.0	GRF2_ARATH; Growth-regulating factor 2
TrEMBL	A0A178UXW8	0.0	A0A178UXW8_ARATH; GRF2
STRING	AT4G37740.1	0.0	(Arabidopsis thaliana)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM1454	28	86

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G37740.1	0.0	growth-regulating factor 2

Publications ? help Back to Top
Casadevall R,Rodriguez RE,Debernardi JM,Palatnik JF,Casati P Repression of growth regulating factors by the microRNA396 inhibits cell proliferation by UV-B radiation in Arabidopsis leaves. Plant Cell, 2013. 25(9): p. 3570-83 [PMID:24076976] Liu J,Rice JH,Chen N,Baum TJ,Hewezi T Synchronization of developmental processes and defense signaling by growth regulating transcription factors. PLoS ONE, 2014. 9(5): p. e98477 [PMID:24875638] Cao Y,Han Y,Jin Q,Lin Y,Cai Y Comparative Genomic Analysis of the GRF Genes in Chinese Pear (Pyrus bretschneideri Rehd), Poplar (Populous), Grape (Vitis vinifera), Arabidopsis and Rice (Oryza sativa). Front Plant Sci, 2016. 7: p. 1750 [PMID:27933074]