PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID 462896455
Organism
Eragrostis tef
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; PACMAD clade; Chloridoideae; Eragrostideae; Eragrostidinae; Eragrostis
Family C2H2
Protein Properties Length: 197aa    MW: 22028.6 Da    PI: 6.5055
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
462896455genomeTefView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H212.40.000474668323
               ET..TTTEEESSHHHHHHHHHHT CS
    zf-C2H2  3 Cp..dCgksFsrksnLkrHirtH 23
               C+   Cgk F +   L++H  +H
  462896455 46 CSyeGCGKIFIDAGALRKHAHVH 68
               77779**************9887 PP
2zf-C2H216.23e-057397123
               EEET..TTTEEESSHHHHHHHHHHT CS
    zf-C2H2  1 ykCp..dCgksFsrksnLkrHirtH 23
               y C+  +Cgk F ++s LkrH   H
  462896455 73 YICHyeNCGKKFLDSSKLKRHFLIH 97
               89*******************8877 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:3.30.160.602.4E-134070IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS5015710.3884473IPR007087Zinc finger, C2H2
SMARTSM003550.00794468IPR015880Zinc finger, C2H2-like
SuperFamilySSF576676.48E-74569No hitNo description
PROSITE patternPS0002804668IPR007087Zinc finger, C2H2
SuperFamilySSF576671.05E-1068110No hitNo description
Gene3DG3DSA:3.30.160.603.3E-147193IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS5015714.06673102IPR007087Zinc finger, C2H2
SMARTSM003550.0137397IPR015880Zinc finger, C2H2-like
PROSITE patternPS0002807597IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.601.3E-1094112IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0003676Molecular Functionnucleic acid binding
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 197 aa     Download sequence    Send to blast
MVIAGGPCAL YKWVREDRLA SLKAKDKDQG AESAKPEPNT EVLFLCSYEG CGKIFIDAGA  60
LRKHAHVHGE RQYICHYENC GKKFLDSSKL KRHFLIHTGE KNFVCPHEGC GKGSMSKNSH  120
RSKPNVAAKM PPPKIQKHKG GYTTPSPAIN VPGEHQWPGK VLYQDDSEET EEEGDNVEDG  180
WRYRAASSDD EETEDEE
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1ubd_C2e-1937112272PROTEIN (YY1 ZINC FINGER DOMAIN)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtDual-function transcription factor with both repression and activation activities. Binds to 5'-CCATATT-3' motif in target gene promoters (e.g. ABR1) (PubMed:26961720). Binds also to G-rich DNA motif 5'-GGGGGCAGTGG-3' (PubMed:22508367). Regulates the expression of genes involved in diverse cellular pathways, including glucose metabolism, photosynthesis, phototropism and stress response (e.g. salt, drought and osmotic stress) (PubMed:22508367, PubMed:26961720). Regulates plant immunity, especially during necrotrophic fungal infection (e.g. B.cinerea) (PubMed:24451981). Binds to ABR1 promoter and promotes its expression, thus negatively regulating the abscisic acid (ABA) signaling pathway. Represses ABA- and salt-responsive genes expression (PubMed:26961720). {ECO:0000269|PubMed:22508367, ECO:0000269|PubMed:24451981, ECO:0000269|PubMed:26961720}.
Cis-element ? help Back to Top
SourceLink
PlantRegMap462896455
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by abscisic acid (ABA) in an ABI1- and ABI4-dependent manner. Stimulated by stress conditions including high salt, osmotic stress (e.g. mannitol) and dehydration. May be induced by ABI4 but repressed by ABR1. Repressed by darkness but induced by light. {ECO:0000269|PubMed:26961720}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_004952831.14e-72zinc finger transcription factor YY1
RefseqXP_025810580.14e-72zinc finger transcription factor YY1
SwissprotQ2V3L31e-44YY1_ARATH; Zinc finger transcription factor YY1
TrEMBLA0A1D6HAB11e-85A0A1D6HAB1_MAIZE; WREBP-2 protein
STRINGPavir.Ab01903.1.p1e-71(Panicum virgatum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MonocotsOGMP20943899
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G06634.19e-47C2H2 family protein
Publications ? help Back to Top
  1. Kumekawa N,Hosouchi T,Tsuruoka H,Kotani H
    The size and sequence organization of the centromeric region of Arabidopsis thaliana chromosome 4.
    DNA Res., 2001. 8(6): p. 285-90
    [PMID:11853315]
  2. Li T,Wu XY,Li H,Song JH,Liu JY
    A Dual-Function Transcription Factor, AtYY1, Is a Novel Negative Regulator of the Arabidopsis ABA Response Network.
    Mol Plant, 2016. 9(5): p. 650-661
    [PMID:26961720]
  3. Wu XY,Li T
    A Casein Kinase II Phosphorylation Site in AtYY1 Affects Its Activity, Stability, and Function in the ABA Response.
    Front Plant Sci, 2017. 8: p. 323
    [PMID:28348572]