PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Sopen04g001760.1
Organism
Solanum pennellii
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum; Lycopersicon
Family MYB
Protein Properties Length: 462aa    MW: 52604.4 Da    PI: 7.1577
Description MYB family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Sopen04g001760.1genomespennView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Myb_DNA-binding27.66.7e-095697748
                      HHHHHHHHHHHHTTTT.-HHHHHHHHTTTS-HHHHHHHHHHHT CS
   Myb_DNA-binding  7 eEdellvdavkqlGgg.tWktIartmgkgRtlkqcksrwqkyl 48
                      +Ed++l + ++ +G + +W+ Ia+ +   +t  qck rw++yl
  Sopen04g001760.1 56 QEDDILREQIRIHGIDdNWTIIASNFK-DKTTRQCKRRWFTYL 97
                      7*************************9.*************97 PP
2Myb_DNA-binding42.51.5e-13103145145
                       TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHH CS
   Myb_DNA-binding   1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwq 45 
                       rg W++eEd ll  a k +G++ W+ Ia+ +  gRt++ +k+r+ 
  Sopen04g001760.1 103 RGGWSPEEDMLLCAAQKIFGNR-WTEIAKVVS-GRTDNAVKNRFT 145
                       789*******************.*********.**********96 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM007177.1E-74999IPR001005SANT/Myb domain
Gene3DG3DSA:1.10.10.602.5E-1656104IPR009057Homeodomain-like
PfamPF002491.6E-75697IPR001005SANT/Myb domain
PROSITE profilePS500908.3515697IPR017877Myb-like domain
CDDcd001672.28E-75697No hitNo description
SuperFamilySSF466894.87E-2477157IPR009057Homeodomain-like
PROSITE profilePS5129419.7498152IPR017930Myb domain
SMARTSM007172.8E-14102150IPR001005SANT/Myb domain
PfamPF002491.3E-11103145IPR001005SANT/Myb domain
Gene3DG3DSA:1.10.10.602.2E-19105151IPR009057Homeodomain-like
CDDcd001672.89E-10106147No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 462 aa     Download sequence    Send to blast
MIDWLVIVLF VLVLFELIVF VPSHIWSPDA KEAGPTLVFT LIHAATSCID VCFVLQEDDI  60
LREQIRIHGI DDNWTIIASN FKDKTTRQCK RRWFTYLNSD FKRGGWSPEE DMLLCAAQKI  120
FGNRWTEIAK VVSGRTDNAV KNRFTTICKK KAKHEAMAEE NRVTLSNKLD TDRICDVSAK  180
KLRRSHTIQS SVDDCPNNNQ PVRHPFAVLA QNVNNLKETH ENGTVLKKND RNMLMQQEEI  240
LSSLALKVNS QNSNQRLENA WMVVDDFLHR MKESDMLKFR HTEMNSVHNT HKNLITNSSS  300
NERNRSSKRQ LALSQESGDS SEYNTGSTQL SRALSNKTEE SQVKTCTRDQ EIQSGLQNFQ  360
IGDQTGVQEL ENGIFCDLSF PHDTRSVCDE MKHDDVSATD GCEYPSPLQV TPQFRSLAEA  420
IPSPKFSESE RQFLLKTLGV ESTSPHRTTK PPSCKRALLQ SL
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1a5j_A2e-215615113107B-MYB
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that binds to DNA in promoters cis-regulatory element 5'-GGCGCGC-3' of cell cycle genes, including cyclins, cyclin-dependent kinases (CDKs), and components of the pre-replication complex (PubMed:20675570, PubMed:24687979). Binds to DNA in promoters cis-regulatory element 5'-AGCCG-3' of auxin regulated genes (e.g. PIN3 and PIN7) (PubMed:26578169). Together with FAMA and MYB88, ensures that stomata contain just two guard cells (GCs) by enforcing a single symmetric precursor cell division before stomatal maturity (PubMed:24571519). Represses the expression of the mitosis-inducing factors CDKB1-1 and CDKA-1, specifically required for the last guard mother cells (GMC) symmetric divisions in the stomatal pathway (PubMed:20675570, PubMed:24687979). Represses CYCA2-3 in newly formed guard cells (PubMed:21772250). Together with MYB88, regulates stomata spacing by restricting divisions late in the stomatal cell lineage thus limiting the number of GMC divisions (PubMed:11536724, PubMed:9684356, PubMed:16155180, PubMed:24123248). In collaboration with CDKB1-1 and CDKB1-2, restrict the G1/S transition and chloroplast and nuclear number during stomatal formation, and normally maintain fate and developmental progression throughout the stomatal cell lineage (PubMed:24123248). Also involved in the shape regulation of pavement cells (PubMed:9684356). Involved in sensing and/or transducing abiotic stress (e.g. drought and salt), probably via the positive regulation of NAC019 (PubMed:21105921). Regulates female reproduction being required for entry into megasporogenesis, probably via the regulation of cell cycle genes (PubMed:22915737). Promotes histone H3K27me3 marks and represses stem cell gene expression (PubMed:24654956). Required for lateral roots (LRs) initiation via the regulation of PIN3 expression in an auxin-dependent manner (PubMed:26578065). Involved in responses to gravity stimulation in primary roots by regulating the transcription of PIN3 and PIN7 in gravity-sensing cells, thus modulating auxin asymmetric redistribution (PubMed:26578169). {ECO:0000269|PubMed:11536724, ECO:0000269|PubMed:16155180, ECO:0000269|PubMed:20675570, ECO:0000269|PubMed:21105921, ECO:0000269|PubMed:21772250, ECO:0000269|PubMed:22915737, ECO:0000269|PubMed:24123248, ECO:0000269|PubMed:24571519, ECO:0000269|PubMed:24654956, ECO:0000269|PubMed:24687979, ECO:0000269|PubMed:26578065, ECO:0000269|PubMed:26578169, ECO:0000269|PubMed:9684356}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Strongly induced by auxin in a IAA14/SLR1 and ARF7 dependent manner, especially in xylem pole pericycle cells, lateral roots initiating cells. {ECO:0000269|PubMed:26578065}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankHG9754431e-120HG975443.1 Solanum pennellii chromosome ch04, complete genome.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_027772147.10.0transcription factor MYB124-like
SwissprotQ94FL61e-115MY124_ARATH; Transcription factor MYB124
TrEMBLM1CJI20.0M1CJI2_SOLTU; Uncharacterized protein
STRINGPGSC0003DMT4000687980.0(Solanum tuberosum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA41242134
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G14350.21e-106MYB family protein
Publications ? help Back to Top
  1. Yang M,Sack FD
    The too many mouths and four lips mutations affect stomatal production in Arabidopsis.
    Plant Cell, 1995. 7(12): p. 2227-39
    [PMID:11536724]
  2. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  3. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  4. Yang K, et al.
    Requirement for A-type cyclin-dependent kinase and cyclins for the terminal division in the stomatal lineage of Arabidopsis.
    J. Exp. Bot., 2014. 65(9): p. 2449-61
    [PMID:24687979]
  5. Yang M
    The FOUR LIPS (FLP) and MYB88 genes conditionally suppress the production of nonstomatal epidermal cells in Arabidopsis cotyledons.
    Am. J. Bot., 2016. 103(9): p. 1559-66
    [PMID:27620181]
  6. Xie Y, et al.
    An atypical R2R3 MYB transcription factor increases cold hardiness by CBF-dependent and CBF-independent pathways in apple.
    New Phytol., 2018. 218(1): p. 201-218
    [PMID:29266327]