PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Sme2.5_00555.1_g00005.1

Organism

Solanum melongena

Taxonomic ID

4111

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum

Family

TCP

Protein Properties

Length: 498aa MW: 54535.1 Da PI: 10.7673

Description

TCP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Sme2.5_00555.1_g00005.1	genome	EGD	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	TCP	117	2.3e-36	161	289	2	89
TCP 2 agkkdrhskihTkvggRdRRvRlsaecaarfFdLqdeLGfdkdsktieWLlqqakpaikeltgt.........ssssasec..eae 76 +g+kdrhsk++T++g+RdRRvRlsa++a++f+d+qd+LG+d++sk+++WL+++akpai+el+++ sa ++ + + Sme2.5_00555.1_g00005.1 161 TGRKDRHSKVCTAKGPRDRRVRLSAHTAIQFYDVQDRLGYDRPSKAVDWLIKKAKPAIDELAELpawkptigsA--SAAATntNLD 244 79**************************************************************8888866431..2212222222 PP TCP 77 sssssasnsssg................................k 89 +++ +++++ s+ + Sme2.5_00555.1_g00005.1 245 QEQAQKQQEDSNfafqqgnaslfdnvagpsskrametnssamqfH 289 222222222222445555555555555444433322222222221 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF03634	1.6E-33	161	307	IPR005333	Transcription factor, TCP
PROSITE profile	PS51369	34.543	163	221	IPR017887	Transcription factor TCP subgroup

Sequence ? help Back to Top
Protein Sequence Length: 498 aa Download sequence Send to blast
MAESFRFQSG ARYRRRRTIQ KRKLKCNQSK AGKRKAEQGS ESGSSEESTP PPSSSSSSSS 60 SSQSKPESRS WQRRRRKSRT IRKRTPTLST SSTTSISSSP SVALWKPSPK KRSYLPSSSS 120 LGQNVEHATL RGKMGETSRL GLRNTVGEIV EVQGGHIVRS TGRKDRHSKV CTAKGPRDRR 180 VRLSAHTAIQ FYDVQDRLGY DRPSKAVDWL IKKAKPAIDE LAELPAWKPT IGSASAAATN 240 TNLDQEQAQK QQEDSNFAFQ QGNASLFDNV AGPSSKRAME TNSSAMQFHS FQESHLLSRT 300 NSQNQDLSLS LQFQDPILLH HQNQQAQHHN QREQEQVQVQ APAHFTGNTP LGFGPSGWSM 360 HQRLSSWSDS RDNAPSGSGG AVTGASGYLF NSPPAPALLQ HLFGQNQFFS QRGPLQSSNT 420 SSVRAMMDPS TIAIASGDPS HHHQAVLPMY PSSIPGYGFA SEVGGFSGFR IPARIQGEEE 480 EHDGISDKPS SASSDSRH

Sequence ? help Back to Top

Protein Sequence Length: 498 aa Download sequence Send to blast

MAESFRFQSG ARYRRRRTIQ KRKLKCNQSK AGKRKAEQGS ESGSSEESTP PPSSSSSSSS  60
SSQSKPESRS WQRRRRKSRT IRKRTPTLST SSTTSISSSP SVALWKPSPK KRSYLPSSSS  120
LGQNVEHATL RGKMGETSRL GLRNTVGEIV EVQGGHIVRS TGRKDRHSKV CTAKGPRDRR  180
VRLSAHTAIQ FYDVQDRLGY DRPSKAVDWL IKKAKPAIDE LAELPAWKPT IGSASAAATN  240
TNLDQEQAQK QQEDSNFAFQ QGNASLFDNV AGPSSKRAME TNSSAMQFHS FQESHLLSRT  300
NSQNQDLSLS LQFQDPILLH HQNQQAQHHN QREQEQVQVQ APAHFTGNTP LGFGPSGWSM  360
HQRLSSWSDS RDNAPSGSGG AVTGASGYLF NSPPAPALLQ HLFGQNQFFS QRGPLQSSNT  420
SSVRAMMDPS TIAIASGDPS HHHQAVLPMY PSSIPGYGFA SEVGGFSGFR IPARIQGEEE  480
EHDGISDKPS SASSDSRH

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5zkt_A	6e-19	168	221	1	54	Putative transcription factor PCF6
5zkt_B	6e-19	168	221	1	54	Putative transcription factor PCF6
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Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor playing a pivotal role in the control of morphogenesis of shoot organs by negatively regulating the expression of boundary-specific genes such as CUC genes, probably through the induction of miRNA (e.g. miR164) (PubMed:12931144, PubMed:17307931). Required during early steps of embryogenesis (PubMed:15634699). Participates in ovule develpment (PubMed:25378179). Activates LOX2 expression by binding to the 5'-GGACCA-3' motif found in its promoter (PubMed:18816164). {ECO:0000269\|PubMed:12931144, ECO:0000269\|PubMed:15634699, ECO:0000269\|PubMed:17307931, ECO:0000269\|PubMed:18816164, ECO:0000269\|PubMed:25378179}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Repressed by the miRNA miR-JAW/miR319 (PubMed:12931144, PubMed:18816164). {ECO:0000269\|PubMed:12931144, ECO:0000269\|PubMed:18816164}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	HM210876	0.0	HM210876.1 Solanum melongena lanceolate gene, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006348284.1	0.0	PREDICTED: transcription factor TCP4-like
Swissprot	Q8LPR5	6e-81	TCP4_ARATH; Transcription factor TCP4
TrEMBL	E2FYM2	0.0	E2FYM2_SOLME; Lanceolate
STRING	PGSC0003DMT400032269	0.0	(Solanum tuberosum)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA3207	23	49

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G15030.3	8e-75	TCP family protein

Publications ? help Back to Top
Schommer C, et al. Control of jasmonate biosynthesis and senescence by miR319 targets. PLoS Biol., 2008. 6(9): p. e230 [PMID:18816164] Ju Y, et al. Arabidopsis JINGUBANG Is a Negative Regulator of Pollen Germination That Prevents Pollination in Moist Environments. Plant Cell, 2016. 28(9): p. 2131-2146 [PMID:27468890] Challa KR,Aggarwal P,Nath U Activation of YUCCA5 by the Transcription Factor TCP4 Integrates Developmental and Environmental Signals to Promote Hypocotyl Elongation in Arabidopsis. Plant Cell, 2016. 28(9): p. 2117-2130 [PMID:27597774] Alvarez JP,Furumizu C,Efroni I,Eshed Y,Bowman JL Active suppression of a leaf meristem orchestrates determinate leaf growth. Elife, 2017. [PMID:27710768] Li J, et al. RABBIT EARS regulates the transcription of TCP4 during petal development in Arabidopsis. J. Exp. Bot., 2016. 67(22): p. 6473-6480 [PMID:27838638] Sun X, et al. Activation of secondary cell wall biosynthesis by miR319-targeted TCP4 transcription factor. Plant Biotechnol. J., 2017. 15(10): p. 1284-1294 [PMID:28233945] Kubota A, et al. TCP4-dependent induction of CONSTANS transcription requires GIGANTEA in photoperiodic flowering in Arabidopsis. PLoS Genet., 2017. 13(6): p. e1006856 [PMID:28628608] Koyama T,Sato F,Ohme-Takagi M Roles of miR319 and TCP Transcription Factors in Leaf Development. Plant Physiol., 2017. 175(2): p. 874-885 [PMID:28842549] Bresso EG,Chorostecki U,Rodriguez RE,Palatnik JF,Schommer C Spatial Control of Gene Expression by miR319-Regulated TCP Transcription Factors in Leaf Development. Plant Physiol., 2018. 176(2): p. 1694-1708 [PMID:29133375] Vadde BVL,Challa KR,Nath U The TCP4 transcription factor regulates trichome cell differentiation by directly activating GLABROUS INFLORESCENCE STEMS in Arabidopsis thaliana. Plant J., 2018. 93(2): p. 259-269 [PMID:29165850] Challa KR,Rath M,Nath U The CIN-TCP transcription factors promote commitment to differentiation in Arabidopsis leaf pavement cells via both auxin-dependent and independent pathways. PLoS Genet., 2019. 15(2): p. e1007988 [PMID:30742619]