PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Niben101Scf02279g05008.1
Organism
Nicotiana benthamiana
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana
Family MYB
Protein Properties Length: 482aa    MW: 54350.9 Da    PI: 6.1125
Description MYB family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Niben101Scf02279g05008.1genomeBTI-
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Myb_DNA-binding33.78.5e-113676748
                              HHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS
           Myb_DNA-binding  7 eEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48
                              +Ed++l + ++ +G+++W+ Ia+++   +t  qc+ rw++yl
  Niben101Scf02279g05008.1 36 QEDDILREQIRIHGTDNWTIIASKFK-DKTTRQCRRRWFTYL 76
                              7************************9.*************97 PP
2Myb_DNA-binding43.95.7e-1482125146
                               TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHH CS
           Myb_DNA-binding   1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqk 46 
                               +g W++eEd ll +a k +G++ W+ Ia+ +  gRt++ +k+r+ +
  Niben101Scf02279g05008.1  82 KGGWSPEEDMLLCEAQKIFGNR-WTEIAKVVS-GRTDNAVKNRFTT 125
                               688*******************.*********.**********976 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS512949.9581776IPR017930Myb domain
SMARTSM007175.7E-62178IPR001005SANT/Myb domain
CDDcd001674.40E-102476No hitNo description
PfamPF139212.2E-123693No hitNo description
Gene3DG3DSA:1.10.10.601.5E-173683IPR009057Homeodomain-like
SuperFamilySSF466893.33E-2555135IPR009057Homeodomain-like
PROSITE profilePS5129420.11277131IPR017930Myb domain
SMARTSM007174.3E-1581129IPR001005SANT/Myb domain
Gene3DG3DSA:1.10.10.608.5E-2084130IPR009057Homeodomain-like
CDDcd001674.53E-1185126No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 482 aa     Download sequence    Send to blast
MQQNMKKSSN SCEAAKPKER HIVSWSQEWI YFYELQEDDI LREQIRIHGT DNWTIIASKF  60
KDKTTRQCRR RWFTYLNSDF KKGGWSPEED MLLCEAQKIF GNRWTEIAKV VSGRTDNAVK  120
NRFTTLCKKR AKHEALAKEN SNSFVNLNNK RVIFPDGLNI DNITEAAAPF KKLRTSHSGE  180
KTFGDCGTTH PLLRHPFAVL AQNFCTAGKN LASHQQTTEN DNKTQGTFLK KDDPKVQALM  240
QQAELLSSLA MKVNTENTDQ SLENAWKVRP MFFILQDFLH QTKEGDMPKF QIPEMNLGPD  300
DYKDLIADSK SSNEGSRPSW RQPALSEDSA GSSEYSTGST LLSHVLPDKT EESQAEVCAH  360
QQDIESELRT SQMSDQGAEL LYADTCGDCI ISDTLPVCGE EKRNDGPATA TAECEFLDTD  420
FSSPLQVTPL FRSLAAEIPT PKFSESERQF LLKTLGVEST SPYPGTNHTQ PPSCKRALLH  480
SL
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1a5j_A1e-243613013107B-MYB
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that binds to DNA in promoters cis-regulatory element 5'-GGCGCGC-3' of cell cycle genes, including cyclins, cyclin-dependent kinases (CDKs), and components of the pre-replication complex (PubMed:20675570, PubMed:24687979). Binds to DNA in promoters cis-regulatory element 5'-AGCCG-3' of auxin regulated genes (e.g. PIN3 and PIN7) (PubMed:26578169). Together with FAMA and MYB124, ensures that stomata contain just two guard cells (GCs) by enforcing a single symmetric precursor cell division before stomatal maturity (PubMed:24571519). Represses the expression of the mitosis-inducing factors CDKB1-1 and CDKA-1, specifically required for the last guard mother cells (GMC) symmetric divisions in the stomatal pathway (PubMed:20675570, PubMed:24687979). Represses CYCA2-3 in newly formed guard cells (PubMed:21772250). Together with MYB88, regulates stomata spacing by restricting divisions late in the stomatal cell lineage thus limiting the number of GMC divisions (PubMed:16155180). In collaboration with CDKB1-1 and CDKB1-2, restrict the G1/S transition and chloroplast and nuclear number during stomatal formation, and normally maintain fate and developmental progression throughout the stomatal cell lineage (PubMed:24123248). Involved in sensing and/or transducing abiotic stress (e.g. drought and salt), probably via the positive regulation of NAC019 (PubMed:21105921). Regulates female reproduction being required for entry into megasporogenesis, probably via the regulation of cell cycle genes (PubMed:22915737). Plays a minor role in lateral roots (LRs) initiation (PubMed:26578065). Involved complementarily in establishing the gravitropic set-point angles of lateral roots by regulating the transcription of PIN3 and PIN7 in gravity-sensing cells of primary and lateral roots (PubMed:26578169). {ECO:0000269|PubMed:16155180, ECO:0000269|PubMed:20675570, ECO:0000269|PubMed:21105921, ECO:0000269|PubMed:21772250, ECO:0000269|PubMed:22915737, ECO:0000269|PubMed:24123248, ECO:0000269|PubMed:24571519, ECO:0000269|PubMed:24687979, ECO:0000269|PubMed:26578065, ECO:0000269|PubMed:26578169}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_019252040.10.0PREDICTED: transcriptional activator Myb
RefseqXP_019252041.10.0PREDICTED: transcriptional activator Myb
RefseqXP_019252043.10.0PREDICTED: transcriptional activator Myb
SwissprotF4IRB41e-161MYB88_ARATH; Transcription factor MYB88
TrEMBLA0A1J6INM80.0A0A1J6INM8_NICAT; Transcription factor myb98
STRINGXP_009778520.10.0(Nicotiana sylvestris)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA41242134
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G02820.21e-163myb domain protein 88
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  3. Yang K, et al.
    Requirement for A-type cyclin-dependent kinase and cyclins for the terminal division in the stomatal lineage of Arabidopsis.
    J. Exp. Bot., 2014. 65(9): p. 2449-61
    [PMID:24687979]
  4. Yang M
    The FOUR LIPS (FLP) and MYB88 genes conditionally suppress the production of nonstomatal epidermal cells in Arabidopsis cotyledons.
    Am. J. Bot., 2016. 103(9): p. 1559-66
    [PMID:27620181]
  5. Xu Z, et al.
    DGE-seq analysis of MUR3-related Arabidopsis mutants provides insight into how dysfunctional xyloglucan affects cell elongation.
    Plant Sci., 2017. 258: p. 156-169
    [PMID:28330559]
  6. Qu Y, et al.
    Peroxisomal CuAOζ and its product H2O2 regulate the distribution of auxin and IBA-dependent lateral root development in Arabidopsis.
    J. Exp. Bot., 2017. 68(17): p. 4851-4867
    [PMID:28992128]
  7. Xie Y, et al.
    An atypical R2R3 MYB transcription factor increases cold hardiness by CBF-dependent and CBF-independent pathways in apple.
    New Phytol., 2018. 218(1): p. 201-218
    [PMID:29266327]