PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Medtr1g100970.1

Common Name

MTR_1g100970

Organism

Medicago truncatula

Taxonomic ID

3880

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Trifolieae; Medicago

Family

Nin-like

Protein Properties

Length: 980aa MW: 108733 Da PI: 5.3619

Description

Nin-like family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Medtr1g100970.1	genome	Mt	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	RWP-RK	90.6	1.3e-28	571	621	2	52
RWP-RK 2 ekeisledlskyFslpikdAAkeLgvclTvLKriCRqyGIkRWPhRkiksl 52 ek+isle+l++yF++++kdAAk+Lgvc+T++KriCRq+GI+RWP+Rki+++ Medtr1g100970.1 571 EKSISLEVLQRYFAGSLKDAAKSLGVCPTTMKRICRQHGISRWPSRKINKV 621 799**********************************************97 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51519	17.461	560	641	IPR003035	RWP-RK domain
Pfam	PF02042	1.7E-25	574	621	IPR003035	RWP-RK domain
SuperFamily	SSF54277	6.21E-22	880	969	No hit	No description
Pfam	PF00564	1.2E-18	883	965	IPR000270	PB1 domain
SMART	SM00666	2.6E-25	883	966	IPR000270	PB1 domain
Gene3D	G3DSA:3.10.20.240	4.2E-26	883	965	No hit	No description
PROSITE profile	PS51745	24.446	883	966	IPR000270	PB1 domain
CDD	cd06407	4.51E-33	884	965	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009414	Biological Process	response to water deprivation
GO:0010118	Biological Process	stomatal movement
GO:0010167	Biological Process	response to nitrate
GO:0042128	Biological Process	nitrate assimilation
GO:0005634	Cellular Component	nucleus
GO:0005515	Molecular Function	protein binding

Sequence ? help Back to Top
Protein Sequence Length: 980 aa Download sequence Send to blast
MSEPEEENQD FPPKTKTSLE EHGCSMDFDL DLETSWPLDH MSFITNPMSP FLFSNISDQP 60 SSPLWTFTDG EDGKLAASAL SDCHKIFSCD SNSITEKLVE KDDNKTLLPP LLPPIENLDG 120 YCVIKEKMTQ ALRYFKEWTE LNVLAQVWAP VRNGNRYVLT TSGQPFVLDP HSNGLNQYRT 180 VSLMYMFSVD GENDGTLGLP GRVFQQKLPE WSPNVLYYSN KEYPRRDHAQ HYNVRGTLAL 240 PVFEPSLQSC IGVIELIMTS LKINYAPEVE KICKALEAVN LRSSEFLDHP FTQICNEGRQ 300 NALSEILEIL TVVCETHNLP LAQTWVPCRH RSVLAHGGGF KKSCSSFDGS CMGQVCMSTT 360 EAAAYIVDAH LWGFREACVE HHLQQGQGVA GRAFLSQTMS FCTNITQFCK TDYPLVHYAL 420 MFGLTSCFAI CLRSFHTGND DYVLEFFLPP GITEFHEQKT LLGSIFSTMK QHFQSLNIAA 480 GVELEENGSI EIIEATDEGI RLRTESIPIA QSIKSPPRPD ASPNMEDEEE GVPQDPSEVR 540 GENVGGSVDP MSTLGNKNIK KPSERKRGKT EKSISLEVLQ RYFAGSLKDA AKSLGVCPTT 600 MKRICRQHGI SRWPSRKINK VNRSLSKLKR VIDSVQRAEG AFDLNSLGNN QLPIVSSFPE 660 PSTLNKSSQQ GSLSNRPSEP QMKENEFDAS KVSETNLQIV MENQLLGGRK HSLEKEVING 720 KGVTIQEIGK DRKRNRTRSG SSEDSTNPTS HGSCHGSPPI EIPTIKDLFI PSNNEQHVVL 780 RRSPEPGMQP TNALNSPTAH RMVDNVIAEL QEPFGGLLIE DAGSSKDLRN LCPSVAEAIL 840 EDMAPEACGN NFPGSSHLAP PKQCIDTINN SATPFAARKE MKTVTIKATY REDIIRFRVS 900 LNCGIVELKE EVSKRLKLEV GTFDIKYMDD DNEWVLIACD ADLQECMYLS RSSGGSNIIR 960 VLVHDITSNL GSSCESSGE*

Sequence ? help Back to Top

Protein Sequence Length: 980 aa Download sequence Send to blast

MSEPEEENQD FPPKTKTSLE EHGCSMDFDL DLETSWPLDH MSFITNPMSP FLFSNISDQP  60
SSPLWTFTDG EDGKLAASAL SDCHKIFSCD SNSITEKLVE KDDNKTLLPP LLPPIENLDG  120
YCVIKEKMTQ ALRYFKEWTE LNVLAQVWAP VRNGNRYVLT TSGQPFVLDP HSNGLNQYRT  180
VSLMYMFSVD GENDGTLGLP GRVFQQKLPE WSPNVLYYSN KEYPRRDHAQ HYNVRGTLAL  240
PVFEPSLQSC IGVIELIMTS LKINYAPEVE KICKALEAVN LRSSEFLDHP FTQICNEGRQ  300
NALSEILEIL TVVCETHNLP LAQTWVPCRH RSVLAHGGGF KKSCSSFDGS CMGQVCMSTT  360
EAAAYIVDAH LWGFREACVE HHLQQGQGVA GRAFLSQTMS FCTNITQFCK TDYPLVHYAL  420
MFGLTSCFAI CLRSFHTGND DYVLEFFLPP GITEFHEQKT LLGSIFSTMK QHFQSLNIAA  480
GVELEENGSI EIIEATDEGI RLRTESIPIA QSIKSPPRPD ASPNMEDEEE GVPQDPSEVR  540
GENVGGSVDP MSTLGNKNIK KPSERKRGKT EKSISLEVLQ RYFAGSLKDA AKSLGVCPTT  600
MKRICRQHGI SRWPSRKINK VNRSLSKLKR VIDSVQRAEG AFDLNSLGNN QLPIVSSFPE  660
PSTLNKSSQQ GSLSNRPSEP QMKENEFDAS KVSETNLQIV MENQLLGGRK HSLEKEVING  720
KGVTIQEIGK DRKRNRTRSG SSEDSTNPTS HGSCHGSPPI EIPTIKDLFI PSNNEQHVVL  780
RRSPEPGMQP TNALNSPTAH RMVDNVIAEL QEPFGGLLIE DAGSSKDLRN LCPSVAEAIL  840
EDMAPEACGN NFPGSSHLAP PKQCIDTINN SATPFAARKE MKTVTIKATY REDIIRFRVS  900
LNCGIVELKE EVSKRLKLEV GTFDIKYMDD DNEWVLIACD ADLQECMYLS RSSGGSNIIR  960
VLVHDITSNL GSSCESSGE*

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Expressed in roots, stems, leaves, flowers and siliques. Detected in root hairs, emerging secondary roots, vascular tissues, leaf parenchyma cells and stomata. {ECO:0000269\|PubMed:18826430}.

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor involved in regulation of nitrate assimilation and in transduction of the nitrate signal. {ECO:0000269\|PubMed:18826430}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00449	DAP	Transfer from AT4G24020	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Medtr1g100970.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Not regulated by the N source or by nitrate. {ECO:0000269\|PubMed:18826430}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AC146755	0.0	AC146755.23 Medicago truncatula clone mth2-15i15, complete sequence.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_003592270.1	0.0	protein NLP6 isoform X1
Swissprot	Q84TH9	0.0	NLP7_ARATH; Protein NLP7
TrEMBL	G7IAL8	0.0	G7IAL8_MEDTR; Plant regulator RWP-RK family protein
STRING	AES62521	0.0	(Medicago truncatula)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF4257	34	56

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G24020.1	0.0	NIN like protein 7

Link Out ? help Back to Top
Phytozome	Medtr1g100970.1
Entrez Gene	11421138

Publications ? help Back to Top
Young ND, et al. The Medicago genome provides insight into the evolution of rhizobial symbioses. Nature, 2011. 480(7378): p. 520-4 [PMID:22089132] Xu N, et al. The Arabidopsis NRG2 Protein Mediates Nitrate Signaling and Interacts with and Regulates Key Nitrate Regulators. Plant Cell, 2016. 28(2): p. 485-504 [PMID:26744214] Karve R,Suárez-Román F,Iyer-Pascuzzi AS The Transcription Factor NIN-LIKE PROTEIN7 Controls Border-Like Cell Release. Plant Physiol., 2016. 171(3): p. 2101-11 [PMID:27221617] Yu LH, et al. Overexpression of Arabidopsis NLP7 improves plant growth under both nitrogen-limiting and -sufficient conditions by enhancing nitrogen and carbon assimilation. Sci Rep, 2016. 6: p. 27795 [PMID:27293103] Menz J,Li Z,Schulze WX,Ludewig U Early nitrogen-deprivation responses in Arabidopsis roots reveal distinct differences on transcriptome and (phospho-) proteome levels between nitrate and ammonium nutrition. Plant J., 2016. 88(5): p. 717-734 [PMID:27419465] Yan D, et al. NIN-like protein 8 is a master regulator of nitrate-promoted seed germination in Arabidopsis. Nat Commun, 2016. 7: p. 13179 [PMID:27731416] Guan P, et al. Interacting TCP and NLP transcription factors control plant responses to nitrate availability. Proc. Natl. Acad. Sci. U.S.A., 2017. 114(9): p. 2419-2424 [PMID:28202720] Liu KH, et al. Discovery of nitrate-CPK-NLP signalling in central nutrient-growth networks. Nature, 2017. 545(7654): p. 311-316 [PMID:28489820] Li Z, et al. The Arabidopsis CPSF30-L gene plays an essential role in nitrate signaling and regulates the nitrate transceptor gene NRT1.1. New Phytol., 2017. 216(4): p. 1205-1222 [PMID:28850721] Cao H, et al. Overexpression of the Maize ZmNLP6 and ZmNLP8 Can Complement the Arabidopsis Nitrate Regulatory Mutant nlp7 by Restoring Nitrate Signaling and Assimilation. Front Plant Sci, 2017. 8: p. 1703 [PMID:29051766] Konishi N,Okubo T,Yamaya T,Hayakawa T,Minamisawa K Nitrate Supply-Dependent Shifts in Communities of Root-Associated Bacteria in Arabidopsis. Microbes Environ., 2017. 32(4): p. 314-323 [PMID:29187692] Karve RA,Iyer-Pascuzzi AS Further insights into the role of NIN-LIKE PROTEIN 7 (NLP7) in root cap cell release. Plant Signal Behav, 2018. 13(1): p. e1414122 [PMID:29215953] Zhao L, et al. The Arabidopsis NLP7 gene regulates nitrate signaling via NRT1.1-dependent pathway in the presence of ammonium. Sci Rep, 2018. 8(1): p. 1487 [PMID:29367694]