PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Manes.12G134300.1.p

Organism

Manihot esculenta

Taxonomic ID

3983

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Euphorbiaceae; Crotonoideae; Manihoteae; Manihot

Family

CAMTA

Protein Properties

Length: 1080aa MW: 120906 Da PI: 6.4103

Description

CAMTA family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Manes.12G134300.1.p	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	CG-1	175	9.9e-55	20	136	2	118
CG-1 2 lkekkrwlkneeiaaiLenfekheltlelktrpksgsliLynrkkvryfrkDGyswkkkkdgktvrEdhekLKvggvevlycyYahseen 91 ++ ++rwl++ ei++iL n+++++++ e+++rp+sgsl+L++rk +ryfrkDG++w+kkkdgktv+E+hekLK g+v+vl+cyYah+e n Manes.12G134300.1.p 20 VEARHRWLRPAEICEILRNYKQFRVAPEPQHRPPSGSLLLFDRKALRYFRKDGHNWRKKKDGKTVKEAHEKLKSGSVDVLHCYYAHGEGN 109 6779************************************************************************************ PP CG-1 92 ptfqrrcywlLeeelekivlvhylevk 118 ++fqrr+yw+Leeel++ivlvhy++vk Manes.12G134300.1.p 110 ENFQRRSYWMLEEELSHIVLVHYRDVK 136 **********************985 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51437	79.788	15	141	IPR005559	CG-1 DNA-binding domain
SMART	SM01076	2.9E-76	18	136	IPR005559	CG-1 DNA-binding domain
Pfam	PF03859	8.7E-49	21	135	IPR005559	CG-1 DNA-binding domain
Gene3D	G3DSA:2.60.40.10	8.2E-6	498	585	IPR013783	Immunoglobulin-like fold
SuperFamily	SSF81296	5.6E-17	499	585	IPR014756	Immunoglobulin E-set
Pfam	PF01833	1.3E-5	499	578	IPR002909	IPT domain
SuperFamily	SSF48403	1.2E-14	675	791	IPR020683	Ankyrin repeat-containing domain
CDD	cd00204	1.40E-11	680	789	No hit	No description
Gene3D	G3DSA:1.25.40.20	8.2E-16	687	792	IPR020683	Ankyrin repeat-containing domain
PROSITE profile	PS50297	15.486	697	801	IPR020683	Ankyrin repeat-containing domain
Pfam	PF12796	4.1E-6	702	793	IPR020683	Ankyrin repeat-containing domain
PROSITE profile	PS50088	8.549	730	762	IPR002110	Ankyrin repeat
SMART	SM00248	0.12	730	759	IPR002110	Ankyrin repeat
SMART	SM00248	1100	769	798	IPR002110	Ankyrin repeat
SuperFamily	SSF52540	5.58E-8	898	955	IPR027417	P-loop containing nucleoside triphosphate hydrolase
SMART	SM00015	11	904	926	IPR000048	IQ motif, EF-hand binding site
PROSITE profile	PS50096	7.181	906	934	IPR000048	IQ motif, EF-hand binding site
Pfam	PF00612	0.031	906	925	IPR000048	IQ motif, EF-hand binding site
SMART	SM00015	0.0039	927	949	IPR000048	IQ motif, EF-hand binding site
PROSITE profile	PS50096	9.578	928	952	IPR000048	IQ motif, EF-hand binding site
Pfam	PF00612	2.2E-4	930	949	IPR000048	IQ motif, EF-hand binding site

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009409	Biological Process	response to cold
GO:0010150	Biological Process	leaf senescence
GO:0042742	Biological Process	defense response to bacterium
GO:0050832	Biological Process	defense response to fungus
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0005516	Molecular Function	calmodulin binding

Sequence ? help Back to Top
Protein Sequence Length: 1080 aa Download sequence Send to blast
MAEARSSPIG NQLDILQILV EARHRWLRPA EICEILRNYK QFRVAPEPQH RPPSGSLLLF 60 DRKALRYFRK DGHNWRKKKD GKTVKEAHEK LKSGSVDVLH CYYAHGEGNE NFQRRSYWML 120 EEELSHIVLV HYRDVKGNRA NFNNVKEHED TIPCTQEIED TVPHSEMDTS VSSHFHHDNY 180 QVPAQTADTI SMNSAQASEY EDAESVYNHQ ASSGLHLFLE EQQPAREKID ASLRDHHDPV 240 SLSSGYEGKL SAVPGRDFFS LAHADKAEDT EGASSTFQLQ KHFDLPCWKD ILENFTPGIE 300 SASFRPQFSS QGDTAGIIPK QEDAIPKQLL SNSLPLQKEW QNLEDASSRL SKWAMDQKLH 360 PNSTADLTTS FHEQELLSGD LTNTLELFGT QKSGHSVQND VQLQYSNTDQ SITPEGKSIY 420 SSTVKQLSEE GLKKLDSFSR WMSKELGDVN ESHMQSSSGP YWDAVENENG IDDPKISSRV 480 HLDTYLLGPS LSQDQLFSII DFSPTWVYVG SKIKVLITGR FLKTPEEVEN CKWSCMFGEV 540 EVQAEVIADG VLRCQTPLNK AGMVPFYVTC SDRVACSEVR EFEYRLSQDV NIIDSYSSSS 600 SVMRFGKLLS LNSLSLPKCN TSNIVENTQL SNKISSLLKV HNEEEWNKML KLTSEAGVSL 660 EKVKEELLQK LLKDRLHVWL LQKAAEGGKG PSVLDEGGQG VLHLAAALGY DWALEPTIVA 720 GVSVNFRDIN GWTALHWAAS CGRERTVASL VFLGAAPGAL TDPTPKYPTA RTPADLASAN 780 GHKGIAGYLA ESALSAHLFS LNLDKQDGDV AGVPEAKAGQ IVPEHSTSVN SDGDLPYGLS 840 LKDSLAAVYN ATQAAARIHQ VFRVQSFQKK QLKEFGDDKY GMPHEHALSF IASKALKSGQ 900 HDEPVHAAAT RIQNKFRSWK GRKEFLIIRQ RIVKIQAHVR GHQVRKNYRK IVWSVGIVEK 960 VILRWRRKGS GLRGFKSEAL IGGPSMQDRS PKEDDYDFFK EGRKQTEARS QIALARVKSM 1020 HQYPEARDQY RRLLNVVTEI QETKLVGDQI NNSEATAEFD DLIDVEALFD DDTFMPAAS*

Sequence ? help Back to Top

Protein Sequence Length: 1080 aa Download sequence Send to blast

MAEARSSPIG NQLDILQILV EARHRWLRPA EICEILRNYK QFRVAPEPQH RPPSGSLLLF  60
DRKALRYFRK DGHNWRKKKD GKTVKEAHEK LKSGSVDVLH CYYAHGEGNE NFQRRSYWML  120
EEELSHIVLV HYRDVKGNRA NFNNVKEHED TIPCTQEIED TVPHSEMDTS VSSHFHHDNY  180
QVPAQTADTI SMNSAQASEY EDAESVYNHQ ASSGLHLFLE EQQPAREKID ASLRDHHDPV  240
SLSSGYEGKL SAVPGRDFFS LAHADKAEDT EGASSTFQLQ KHFDLPCWKD ILENFTPGIE  300
SASFRPQFSS QGDTAGIIPK QEDAIPKQLL SNSLPLQKEW QNLEDASSRL SKWAMDQKLH  360
PNSTADLTTS FHEQELLSGD LTNTLELFGT QKSGHSVQND VQLQYSNTDQ SITPEGKSIY  420
SSTVKQLSEE GLKKLDSFSR WMSKELGDVN ESHMQSSSGP YWDAVENENG IDDPKISSRV  480
HLDTYLLGPS LSQDQLFSII DFSPTWVYVG SKIKVLITGR FLKTPEEVEN CKWSCMFGEV  540
EVQAEVIADG VLRCQTPLNK AGMVPFYVTC SDRVACSEVR EFEYRLSQDV NIIDSYSSSS  600
SVMRFGKLLS LNSLSLPKCN TSNIVENTQL SNKISSLLKV HNEEEWNKML KLTSEAGVSL  660
EKVKEELLQK LLKDRLHVWL LQKAAEGGKG PSVLDEGGQG VLHLAAALGY DWALEPTIVA  720
GVSVNFRDIN GWTALHWAAS CGRERTVASL VFLGAAPGAL TDPTPKYPTA RTPADLASAN  780
GHKGIAGYLA ESALSAHLFS LNLDKQDGDV AGVPEAKAGQ IVPEHSTSVN SDGDLPYGLS  840
LKDSLAAVYN ATQAAARIHQ VFRVQSFQKK QLKEFGDDKY GMPHEHALSF IASKALKSGQ  900
HDEPVHAAAT RIQNKFRSWK GRKEFLIIRQ RIVKIQAHVR GHQVRKNYRK IVWSVGIVEK  960
VILRWRRKGS GLRGFKSEAL IGGPSMQDRS PKEDDYDFFK EGRKQTEARS QIALARVKSM  1020
HQYPEARDQY RRLLNVVTEI QETKLVGDQI NNSEATAEFD DLIDVEALFD DDTFMPAAS*

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds to the DNA consensus sequence 5'-[ACG]CGCG[GTC]-3'. Binds calmodulin in a calcium-dependent manner in vitro (PubMed:12218065). Regulates transcriptional activity in response to calcium signals (Probable). Involved in freezing tolerance in association with CAMTA1 and CAMTA2 (PubMed:23581962). Required for the cold-induced expression of DREB1B/CBF1, DREB1C/CBF2, ZAT12 and GOLS3 (PubMed:19270186). Involved in response to cold. Contributes together with CAMTA5 to the positive regulation of the cold-induced expression of DREB1A/CBF3, DREB1B/CBF1 and DREB1C/CBF2 (PubMed:28351986). Involved together with CAMTA2 and CAMTA4 in the positive regulation of a general stress response (GSR) (PubMed:25039701). Involved in the regulation of GSR amplitude downstream of MEKK1 (PubMed:25157030). Involved in the regulation of a set of genes involved in defense responses against pathogens (PubMed:18298954). Involved in the regulation of both basal resistance and systemic acquired resistance (SAR) (PubMed:21900483). Acts as negative regulator of plant immunity (PubMed:19122675, PubMed:21900483, PubMed:22345509, PubMed:28407487). Binds to the promoter of the defense-related gene EDS1 and represses its expression (PubMed:19122675). Binds to the promoter of the defense-related gene NDR1 and represses its expression (PubMed:22345509). Involved in defense against insects (PubMed:23072934, PubMed:22371088). Required for tolerance to the generalist herbivore Trichoplusia ni, and contributes to the positive regulation of genes associated with glucosinolate metabolism (PubMed:23072934). Required for tolerance to Bradysia impatiens larvae. Mediates herbivore-induced wound response (PubMed:22371088). Required for wound-induced jasmonate accumulation (PubMed:23072934, PubMed:22371088). Involved in the regulation of ethylene-induced senescence by binding to the promoter of the senescence-inducer gene EIN3 and repressing its expression (PubMed:22345509). {ECO:0000269\|PubMed:12218065, ECO:0000269\|PubMed:18298954, ECO:0000269\|PubMed:19122675, ECO:0000269\|PubMed:19270186, ECO:0000269\|PubMed:21900483, ECO:0000269\|PubMed:22345509, ECO:0000269\|PubMed:22371088, ECO:0000269\|PubMed:23072934, ECO:0000269\|PubMed:23581962, ECO:0000269\|PubMed:25039701, ECO:0000269\|PubMed:25157030, ECO:0000269\|PubMed:28351986, ECO:0000269\|PubMed:28407487, ECO:0000305\|PubMed:11925432}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00042	PBM	Transfer from AT2G22300	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Manes.12G134300.1.p

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By heat shock, UVB, salt, wounding, ethylene and methyl jasmonate (PubMed:11162426, PubMed:12218065). Induced by infection with the fungal pathogen Golovinomyces cichoracearum (powdery mildew) and the bacterial pathogen Pseudomonas syringae pv tomato strain DC3000 (PubMed:22345509). {ECO:0000269\|PubMed:11162426, ECO:0000269\|PubMed:12218065, ECO:0000269\|PubMed:22345509}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_021630371.1	0.0	calmodulin-binding transcription activator 3 isoform X1
Swissprot	Q8GSA7	0.0	CMTA3_ARATH; Calmodulin-binding transcription activator 3
TrEMBL	A0A2C9UWF7	0.0	A0A2C9UWF7_MANES; Uncharacterized protein
STRING	cassava4.1_000675m	0.0	(Manihot esculenta)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF8284	27	35

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G22300.2	0.0	signal responsive 1

Link Out ? help Back to Top
Phytozome	Manes.12G134300.1.p

Publications ? help Back to Top
Zhang L,Du L,Shen C,Yang Y,Poovaiah BW Regulation of plant immunity through ubiquitin-mediated modulation of Ca(2+) -calmodulin-AtSR1/CAMTA3 signaling. Plant J., 2014. 78(2): p. 269-81 [PMID:24528504] Benn G, et al. A key general stress response motif is regulated non-uniformly by CAMTA transcription factors. Plant J., 2014. 80(1): p. 82-92 [PMID:25039701] Rahman H,Yang J,Xu YP,Munyampundu JP,Cai XZ Phylogeny of Plant CAMTAs and Role of AtCAMTAs in Nonhost Resistance to Xanthomonas oryzae pv. oryzae. Front Plant Sci, 2016. 7: p. 177 [PMID:26973658] Benn G, et al. Plastidial metabolite MEcPP induces a transcriptionally centered stress-response hub via the transcription factor CAMTA3. Proc. Natl. Acad. Sci. U.S.A., 2016. 113(31): p. 8855-60 [PMID:27432993] Kidokoro S, et al. Different Cold-Signaling Pathways Function in the Responses to Rapid and Gradual Decreases in Temperature. Plant Cell, 2017. 29(4): p. 760-774 [PMID:28351986] Lolle S, et al. Matching NLR Immune Receptors to Autoimmunity in camta3 Mutants Using Antimorphic NLR Alleles. Cell Host Microbe, 2017. 21(4): p. 518-529.e4 [PMID:28407487] Kim YS, et al. CAMTA-Mediated Regulation of Salicylic Acid Immunity Pathway Genes in Arabidopsis Exposed to Low Temperature and Pathogen Infection. Plant Cell, 2017. 29(10): p. 2465-2477 [PMID:28982964] Jacob F, et al. A dominant-interfering camta3 mutation compromises primary transcriptional outputs mediated by both cell surface and intracellular immune receptors in Arabidopsis thaliana. New Phytol., 2018. 217(4): p. 1667-1680 [PMID:29226970]