PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MDP0000412781
Organism
Malus domestica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus
Family ARF
Protein Properties Length: 825aa    MW: 91316.1 Da    PI: 6.8658
Description ARF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MDP0000412781genomeGDRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1B373.32.9e-23164265199
                    EEEE-..-HHHHTT-EE--HHH.HTT......---..--SEEEEEETTS-EEEEEE..EEETTEEEE-TTHHHHHHHHT--TT-EEEEEE-SSSEE CS
             B3   1 ffkvltpsdvlksgrlvlpkkfaeeh......ggkkeesktltledesgrsWevkliyrkksgryvltkGWkeFvkangLkegDfvvFkldgrsef 90 
                    f+k+lt sd++++g +++p++ ae++      + +++ s++l+ +d++g +W++++iyr++++r++lt+GW+ F ++++L +gD v+F   + +++
  MDP0000412781 164 FCKTLTASDTSTHGGFSVPRRAAEDCfppldyK-QQRPSQELVAKDLHGVEWRFRHIYRGQPRRHLLTTGWSIFISQKNLVAGDAVLFL--RGENG 256
                    99****************************963.3445679************************************************..44999 PP

                    ..EEEEE-S CS
             B3  91 elvvkvfrk 99 
                    el+++++r+
  MDP0000412781 257 ELRLGIRRA 265
                    99****996 PP
2Auxin_resp122.53e-40290371182
     Auxin_resp   1 aahaastksvFevvYnPrastseFvvkvekvekalkvkvsvGmRfkmafetedsserrlsGtvvgvsdldpvrWpnSkWrsL 82 
                    +a+a+stks+F+v+Y+Pras++eFv++++k++k+++++v+ G+Rfkm+f+ +ds+err+sG+v+g++dldp+rWpnSkWr+L
  MDP0000412781 290 VANAISTKSMFHVFYSPRASHAEFVIPYQKYVKSITNPVTXGTRFKMRFDRDDSPERRCSGVVTGITDLDPFRWPNSKWRCL 371
                    689******************************************************************************9 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF1019363.14E-44156277IPR015300DNA-binding pseudobarrel domain
Gene3DG3DSA:2.40.330.109.1E-41157276IPR015300DNA-binding pseudobarrel domain
CDDcd100173.95E-23162264No hitNo description
SMARTSM010193.0E-24164266IPR003340B3 DNA binding domain
PROSITE profilePS5086312.872164266IPR003340B3 DNA binding domain
PfamPF023621.6E-21164265IPR003340B3 DNA binding domain
PfamPF065078.3E-34290371IPR010525Auxin response factor
SuperFamilySSF542778.44E-10692775No hitNo description
PROSITE profilePS5174521.299696778IPR000270PB1 domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009725Biological Processresponse to hormone
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0005515Molecular Functionprotein binding
Sequence ? help Back to Top
Protein Sequence    Length: 825 aa     Download sequence    Send to blast
MEIDLNHAVR EVEKNAYCNG DCGGVCVYCL SSSTSSSSSN SSSAPVASSI YLELWHACAG  60
PLISLPKKGN VVVYFPQGHL EQVASSSPFS PMEMPTFDLH PQIFCKVVNV QLLANKENDE  120
VYTHVTLLPQ PELVGTNLEG KELEELGVDE GDGGSPTKST PHMFCKTLTA SDTSTHGGFS  180
VPRRAAEDCF PPLDYKQQRP SQELVAKDLH GVEWRFRHIY RGQPRRHLLT TGWSIFISQK  240
NLVAGDAVLF LRGENGELRL GIRRAVRPRN GLPDSVVGNQ NSYPSVLSFV ANAISTKSMF  300
HVFYSPRASH AEFVIPYQKY VKSITNPVTX GTRFKMRFDR DDSPERRCSG VVTGITDLDP  360
FRWPNSKWRC LMVRWDEDIG NDHQERVSXW EVDPSVSLPP LSIQSSPRLK KLRTSLQGTP  420
PIPSITGTIL PNNIASIFYI IIXPQYVNFL AAGGAGFKDF EESVKSSKVL QGQENIGFIS  480
PLYGXDTVNX PQDFEMHAPA HLSLASNATQ KATIDELMRA RRTPYTGFAE SDRFPKVLQG  540
QEICPLRSLT GKANFTLGDW ESNNGCAPFN VYQPPKPNYF SLASGSLPNM YFPYGDXHRA  600
GQDPTMCSNA TNLPREKMQI NPYSMQXGVA RNEVGRPNKP CEHKTQESTS TLPALVPNPR  660
NPNDKDYNGT VTGCKLFGFS LTGDNPSPNS QSSSKRSCTK VHKQGSLVGR AIDLAKLNGY  720
GDLLTELERL FGMXGLLRDS DKGWRILYTD SENDMMVVGD DPWHEFCNVV SKIHIYTREE  780
VEKMTIGMIS DDTQSCLEHA PVMLEVSKSS SVSQPDSSPT AIRV*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4ldy_A1e-122363942354Auxin response factor 1
4ldy_B1e-122363942354Auxin response factor 1
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Mdo.137070.0fruit
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Expressed in the whole plant. {ECO:0000269|PubMed:10476078}.
Functional Description ? help Back to Top
Source Description
UniProtAuxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs). Could act as transcriptional activator or repressor. Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression. {ECO:0000269|PubMed:12036261}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_008385290.20.0auxin response factor 4
SwissprotQ9ZTX90.0ARFD_ARATH; Auxin response factor 4
TrEMBLA0A498IP220.0A0A498IP22_MALDO; Auxin response factor
STRINGXP_008385290.10.0(Malus domestica)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF52363252
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G60450.10.0auxin response factor 4
Publications ? help Back to Top
  1. Ozerova LV,Krasnikova MS,Troitsky AV,Solovyev AG,Morozov SY
    TAS3 Genes for small ta-siARF RNAs in plants belonging to subtribe Senecioninae: occurrence of prematurely terminated RNA precursors.
    Mol. Gen. Mikrobiol. Virusol., 2013.
    [PMID:24003511]
  2. Machida C,Nakagawa A,Kojima S,Takahashi H,Machida Y
    The complex of ASYMMETRIC LEAVES (AS) proteins plays a central role in antagonistic interactions of genes for leaf polarity specification in Arabidopsis.
    Wiley Interdiscip Rev Dev Biol, 2015 Nov-Dec. 4(6): p. 655-71
    [PMID:26108442]
  3. Pashkovskiy PP,Kartashov AV,Zlobin IE,Pogosyan SI,Kuznetsov VV
    Blue light alters miR167 expression and microRNA-targeted auxin response factor genes in Arabidopsis thaliana plants.
    Plant Physiol. Biochem., 2016. 104: p. 146-54
    [PMID:27031426]
  4. Matsumura Y, et al.
    A genetic link between epigenetic repressor AS1-AS2 and a putative small subunit processome in leaf polarity establishment of Arabidopsis.
    Biol Open, 2016. 5(7): p. 942-54
    [PMID:27334696]
  5. Guan C, et al.
    Spatial Auxin Signaling Controls Leaf Flattening in Arabidopsis.
    Curr. Biol., 2017. 27(19): p. 2940-2950.e4
    [PMID:28943086]
  6. Liu Z, et al.
    ARF2-ARF4 and ARF5 are Essential for Female and Male Gametophyte Development in Arabidopsis.
    Plant Cell Physiol., 2018. 59(1): p. 179-189
    [PMID:29145642]