PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MDP0000194603
Common NameARF1
Organism
Malus domestica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus
Family ARF
Protein Properties Length: 702aa    MW: 78388.8 Da    PI: 7.4043
Description ARF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MDP0000194603genomeGDRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1B374.41.3e-23127227198
                    EEEE-..-HHHHTT-EE--HHH.HTT.....---..--SEEEEEETTS-EEEEEE..EEETTEEEE-TTHHHHHHHHT--TT-EEEEEE-SSSEE. CS
             B3   1 ffkvltpsdvlksgrlvlpkkfaeeh.....ggkkeesktltledesgrsWevkliyrkksgryvltkGWkeFvkangLkegDfvvFkldgrsefe 91 
                    f+k+lt sd++++g +++ +k+a+e+     +++ + +++l+ +d++g +W++k+i+r++++r++lt+GW+ Fv +++L +gD +vF   + +++e
  MDP0000194603 127 FCKILTASDTSTHGGFSVLRKHATEClppldMNQATPTQELIAKDLHGYEWKFKHIFRGQPRRHLLTTGWSTFVTSKRLVAGDAFVFL--RGDNGE 220
                    99****************************9555556679************************************************..348999 PP

                    .EEEEE- CS
             B3  92 lvvkvfr 98 
                    l+v+v+r
  MDP0000194603 221 LRVGVRR 227
                    9****98 PP
2Auxin_resp77.92.5e-26253339183
     Auxin_resp   1 aahaastksvFevvYnPrastseFvvkvekvekalkvkvsvGmRfkmafetedsserrl.......sGtvvgvsdldpvrWpnSkWrsLk 83 
                    a+ha+ tk+ F v+ +Pr+  s+F++ ++k+++a+k+k+s+G+Rf+m+fe+++s+err+       +Gt+v v dl+p +W++SkWrsLk
  MDP0000194603 253 ASHALMTKTLFVVYSKPRT--SQFIIGLSKYLEATKTKFSLGTRFRMRFEGDESPERRClhgsrrfTGTIVEVGDLSP-QWSESKWRSLK 339
                    6899**************6..9*********************************998666666669***********.*********96 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:2.40.330.101.6E-40118242IPR015300DNA-binding pseudobarrel domain
SuperFamilySSF1019361.05E-40119256IPR015300DNA-binding pseudobarrel domain
SMARTSM010192.2E-22127229IPR003340B3 DNA binding domain
PfamPF023621.7E-21127227IPR003340B3 DNA binding domain
CDDcd100175.84E-20127227No hitNo description
PROSITE profilePS5086312.196127229IPR003340B3 DNA binding domain
PfamPF065071.6E-23253339IPR010525Auxin response factor
PfamPF023096.3E-7575623IPR033389AUX/IAA domain
SuperFamilySSF542772.35E-10582663No hitNo description
PROSITE profilePS5174522.3587668IPR000270PB1 domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009734Biological Processauxin-activated signaling pathway
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0005515Molecular Functionprotein binding
Sequence ? help Back to Top
Protein Sequence    Length: 702 aa     Download sequence    Send to blast
MAHLECDSSI SRAETDLRGD DLYTELWKLC AGPLVDVPRP GEKVYYFPQG HMEQLESSTN  60
QELNQQIPLF NLPSKILCSV VHIRLLAEQE TDEVYAQITL HPEADQCEPS SPDPCKPEAP  120
KATVHWFCKI LTASDTSTHG GFSVLRKHAT ECLPPLDMNQ ATPTQELIAK DLHGYEWKFK  180
HIFRGQPRRH LLTTGWSTFV TSKRLVAGDA FVFLRGDNGE LRVGVRRLAR QQSQIPSSVI  240
SSQSMHLGVL ATASHALMTK TLFVVYSKPR TSQFIIGLSK YLEATKTKFS LGTRFRMRFE  300
GDESPERRCL HGSRRFTGTI VEVGDLSPQW SESKWRSLKV QWDEHAAVQR PDRVSPWDIE  360
PFVASAPSNL AQPMVKSKRP RPVEISSSEV TTNSAASSFW YHSSPQTTEL NRGGVPEVQT  420
SGSQVVWPLR QKESNSSSYS SARVCSEGIW PSSPHVDVPL SLFRDSKESS KNVIAGSVLS  480
SIASPILSKP NNVLIHDQVE KGKKSDSSGF WLFGCNLSNN TKTTCPQEIE PVFKTMPSGA  540
KGPIPADAFE SDQGLDVSKL SKEQKQVILE ASPKETQGKQ GLTLSTRTRT KVQMQGVAVG  600
RAVDLTALKG YDHLIDELEK MFEIKGELRP KNKWAVVFTD DENDMMLMGD DQWPDFCKLV  660
KKIFIYSSDE VQKMNRCKLQ SSSLDCEGTV SVDSLSIDRK HD
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4ldv_A1e-1632036217355Auxin response factor 1
4ldw_A1e-1632036217355Auxin response factor 1
4ldw_B1e-1632036217355Auxin response factor 1
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1377381KRPRP
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Mdo.112210.0bud| leaf
Functional Description ? help Back to Top
Source Description
UniProtAuxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs). Could act as transcriptional activator or repressor. Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression. {ECO:0000269|PubMed:12036261}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAB6272651e-168AB627265.1 Malus x domestica mRNA, microsatellite: MEST120, clone: FLW01_31_E06.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_001280753.10.0ADP-ribosylation factor 1
SwissprotQ9C5W90.0ARFR_ARATH; Auxin response factor 18
TrEMBLA0A498JGU00.0A0A498JGU0_MALDO; Auxin response factor
STRINGXP_008376146.10.0(Malus domestica)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF15113396
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G23980.10.0auxin response factor 9
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Wójcikowska B,Gaj MD
    Expression profiling of AUXIN RESPONSE FACTOR genes during somatic embryogenesis induction in Arabidopsis.
    Plant Cell Rep., 2017. 36(6): p. 843-858
    [PMID:28255787]