PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Han002216

Organism

Helianthus annuus

Taxonomic ID

4232

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Asterales; Asteraceae; Asteroideae; Heliantheae alliance; Heliantheae; Helianthus

Family

NAC

Protein Properties

Length: 265aa MW: 29926.3 Da PI: 5.2576

Description

NAC family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
gnl\|UG\|Han#S48348089	PU_ref	Unigene	View CDS
PUT-169a-Helianthus_annuus-28963	PU_unref	plantGDB	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	NAM	169.1	1.5e-52	37	164	1	128
NAM 1 lppGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLp..kkvkaeekewyfFskrdkkyatgkrknratksgyWkatgkdkevlskkge 98 l+pGfrFhPtdeelv++yL++k+ gk++++ ++++e+d+yk+ePw+L +++k++++ewyfFs+ d+ky +g+r nrat +gyWkatgkd+ v + k+e Han002216 37 LAPGFRFHPTDEELVMYYLRRKACGKPFRF-QAVTEIDVYKSEPWELAdfSSLKTRDQEWYFFSPVDRKYGNGSRLNRATGQGYWKATGKDRCVRH-KSE 134 579***********************99.88**********85448889999*********************************9.999 PP NAM 99 lvglkktLvfykgrapkgektdWvmheyrl 128 ++g+kktLvf++grap+g++t+Wvmheyrl Han002216 135 TIGMKKTLVFHSGRAPDGKRTNWVMHEYRL 164 **************************97 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF101941	1.28E-62	34	187	IPR003441	NAC domain
PROSITE profile	PS51005	57.676	37	187	IPR003441	NAC domain
Pfam	PF02365	2.2E-28	39	164	IPR003441	NAC domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 265 aa Download sequence Send to blast
XCISVADQKS TNMGQEIIAV ATPATAAAPP PPPPTSLAPG FRFHPTDEEL VMYYLRRKAC 60 GKPFRFQAVT EIDVYKSEPW ELADFSSLKT RDQEWYFFSP VDRKYGNGSR LNRATGQGYW 120 KATGKDRCVR HKSETIGMKK TLVFHSGRAP DGKRTNWVMH EYRLLDHELL RVGVTQDSFV 180 LCRIFQKSGL GPPNGDRYAP FLEEEWNDDA ALMVPGGEAE DDLTNGDETR PEGNDSVQEA 240 IPFVCKRERS EDRAFNSEPE LEPSL

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
3swm_A	1e-53	31	187	14	168	NAC domain-containing protein 19
3swm_B	1e-53	31	187	14	168	NAC domain-containing protein 19
3swm_C	1e-53	31	187	14	168	NAC domain-containing protein 19
3swm_D	1e-53	31	187	14	168	NAC domain-containing protein 19
3swp_A	1e-53	31	187	14	168	NAC domain-containing protein 19
3swp_B	1e-53	31	187	14	168	NAC domain-containing protein 19
3swp_C	1e-53	31	187	14	168	NAC domain-containing protein 19
3swp_D	1e-53	31	187	14	168	NAC domain-containing protein 19
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Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Mostly expressed in floral organs, and, at low levels, in other organs. {ECO:0000269\|PubMed:25578968}.

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional repressor that binds to the motif 5'-(C/T)A(C/A)G-3' in the promoter of target genes (PubMed:25578968). Binds also to the 5'-CTTGNNNNNCAAG-3' consensus sequence in chromatin (PubMed:26617990). Can bind to the mitochondrial dysfunction motif (MDM) present in the upstream regions of mitochondrial dysfunction stimulon (MDS) genes involved in mitochondrial retrograde regulation (MRR) (PubMed:24045019). Together with NAC051/NAC052 and JMJ14, regulates gene expression and flowering time by associating with the histone demethylase JMJ14, probably by the promotion of RNA-mediated gene silencing (PubMed:25578968, PubMed:26617990). {ECO:0000269\|PubMed:24045019, ECO:0000269\|PubMed:25578968, ECO:0000269\|PubMed:26617990}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_021976900.1	0.0	NAC domain-containing protein 78-like
Swissprot	Q9SQX9	3e-98	NAC50_ARATH; NAC domain containing protein 50
TrEMBL	A0A251U4K0	0.0	A0A251U4K0_HELAN; Putative NAC domain-containing protein
STRING	XP_009619467.1	1e-141	(Nicotiana tomentosiformis)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G10490.1	6e-98	NAC domain containing protein 52

Publications ? help Back to Top
Zhang S, et al. C-terminal domains of a histone demethylase interact with a pair of transcription factors and mediate specific chromatin association. Cell Discov, 2019. [PMID:26617990]