PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Glyma.17G248900.1.p
Common NameGLYMA_17G248900, LOC100785743
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Phaseoleae; Glycine; Soja
Family BES1
Protein Properties Length: 312aa    MW: 33986.2 Da    PI: 9.4326
Description BES1 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Glyma.17G248900.1.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
               DUF822   1 ggsgrkptwkErEnnkrRERrRRaiaakiyaGLRaqGnyklpkraDnneVlkALcreAGwvvedDGttyrkgskpleeaeaagssasasp 90 
                          ++s+rkp+w+ErEnn+rRERrRRaiaakiy+GLRaqGn++lpk++DnneVlkALc+eAGw ve+DGttyrkg+kp+  a+ agss ++ p
                          579*************************************************************************.99999****9999 PP

               DUF822  91 esslq.sslkssalaspvesysaspksssfpspssldsislasaasllpvlsvlsl 145
                           ss+q  s+ ss+++sp++sy+ sp+sss psp +ld  +  + ++l+p++++ sl
                          999998******************************99865.46899999988876 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF056871.8E-6112151IPR008540BES1/BZR1 plant transcription factor, N-terminal
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
Sequence ? help Back to Top
Protein Sequence    Length: 312 aa     Download sequence    Send to blast
3D Structure ? help Back to Top
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5zd4_A1e-301395371453Maltose-binding periplasmic protein,Protein BRASSINAZOLE-RESISTANT 1
5zd4_B1e-301395371453Maltose-binding periplasmic protein,Protein BRASSINAZOLE-RESISTANT 1
5zd4_C1e-301395371453Maltose-binding periplasmic protein,Protein BRASSINAZOLE-RESISTANT 1
5zd4_D1e-301395371453Maltose-binding periplasmic protein,Protein BRASSINAZOLE-RESISTANT 1
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
No. Start End Sequence
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Gma.52380.0cotyledon| hypocotyl| root
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Accumulates in the growing region of the hypocotyl. {ECO:0000269|PubMed:11970900}.
Functional Description ? help Back to Top
Source Description
UniProtTranscriptional repressor that binds to the brassinosteroid (BR) response element (BRRE) 5'-CGTG(T/C)G-3' in gene promoter. Regulates positively the brassinosteroid-signaling pathway. Mediates downstream growth responses and negative feedback regulation of brassinosteroid biosynthesis. Promotes growth. Modulates ovule initiation and development by monitoring the expression of genes related to ovule development (e.g. HLL, ANT, and AP2). {ECO:0000269|PubMed:15681342, ECO:0000269|PubMed:22914576}.
Cis-element ? help Back to Top
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By brassinosteroid (BR). {ECO:0000269|PubMed:15681342}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAP0150360.0AP015036.1 Vigna angularis var. angularis DNA, chromosome 3, almost complete sequence, cultivar: Shumari.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006601311.10.0protein BRASSINAZOLE-RESISTANT 1
TrEMBLI1MXU70.0I1MXU7_SOYBN; Uncharacterized protein
STRINGGLYMA17G36730.10.0(Glycine max)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
Representative plantOGRP37191024
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G19350.63e-94BES1 family protein
Publications ? help Back to Top
  1. Wang H, et al.
    Dual role of BKI1 and 14-3-3 s in brassinosteroid signaling to link receptor with transcription factors.
    Dev. Cell, 2011. 21(5): p. 825-34
  2. Liu L, et al.
    Ectopic expression of a BZR1-1D transcription factor in brassinosteroid signalling enhances carotenoid accumulation and fruit quality attributes in tomato.
    Plant Biotechnol. J., 2014. 12(1): p. 105-15
  3. Kim B, et al.
    Darkness and gulliver2/phyB mutation decrease the abundance of phosphorylated BZR1 to activate brassinosteroid signaling in Arabidopsis.
    Plant J., 2014. 77(5): p. 737-47
  4. He X, et al.
    A genotypic difference in primary root length is associated with the inhibitory role of transforming growth factor-beta receptor-interacting protein-1 on root meristem size in wheat.
    Plant J., 2014. 77(6): p. 931-43
  5. Oh E, et al.
    Cell elongation is regulated through a central circuit of interacting transcription factors in the Arabidopsis hypocotyl.
    Elife, 2015.
  6. Zhang D,Jing Y,Jiang Z,Lin R
    The Chromatin-Remodeling Factor PICKLE Integrates Brassinosteroid and Gibberellin Signaling during Skotomorphogenic Growth in Arabidopsis.
    Plant Cell, 2014. 26(6): p. 2472-2485
  7. Shimada S, et al.
    Formation and dissociation of the BSS1 protein complex regulates plant development via brassinosteroid signaling.
    Plant Cell, 2015. 27(2): p. 375-90
  8. Chaiwanon J,Wang ZY
    Spatiotemporal brassinosteroid signaling and antagonism with auxin pattern stem cell dynamics in Arabidopsis roots.
    Curr. Biol., 2015. 25(8): p. 1031-42
  9. Zhang Y, et al.
    Brassinosteroid is required for sugar promotion of hypocotyl elongation in Arabidopsis in darkness.
    Planta, 2015. 242(4): p. 881-93
  10. Jiang J, et al.
    The Intrinsically Disordered Protein BKI1 Is Essential for Inhibiting BRI1 Signaling in Plants.
    Mol Plant, 2015. 8(11): p. 1675-8
  11. Zhang Y,He J
    Sugar-induced plant growth is dependent on brassinosteroids.
    Plant Signal Behav, 2015. 10(12): p. e1082700
  12. Anne P, et al.
    OCTOPUS Negatively Regulates BIN2 to Control Phloem Differentiation in Arabidopsis thaliana.
    Curr. Biol., 2015. 25(19): p. 2584-90
  13. Wang R, et al.
    The Brassinosteroid-Activated BRI1 Receptor Kinase Is Switched off by Dephosphorylation Mediated by Cytoplasm-Localized PP2A B' Subunits.
    Mol Plant, 2016. 9(1): p. 148-157
  14. Youn JH, et al.
    ARF7 increases the endogenous contents of castasterone through suppression of BAS1 expression in Arabidopsis thaliana.
    Phytochemistry, 2016. 122: p. 34-44
  15. Chaiwanon J,Garcia VJ,Cartwright H,Sun Y,Wang ZY
    Immunophilin-like FKBP42/TWISTED DWARF1 Interacts with the Receptor Kinase BRI1 to Regulate Brassinosteroid Signaling in Arabidopsis.
    Mol Plant, 2016. 9(4): p. 593-600
  16. Yang X,Bai Y,Shang J,Xin R,Tang W
    The antagonistic regulation of abscisic acid-inhibited root growth by brassinosteroids is partially mediated via direct suppression of ABSCISIC ACID INSENSITIVE 5 expression by BRASSINAZOLE RESISTANT 1.
    Plant Cell Environ., 2016. 39(9): p. 1994-2003
  17. Shahnejat-Bushehri S,Tarkowska D,Sakuraba Y,Balazadeh S
    Arabidopsis NAC transcription factor JUB1 regulates GA/BR metabolism and signalling.
    Nat Plants, 2016. 2: p. 16013
  18. Zhang Z, et al.
    TOR Signaling Promotes Accumulation of BZR1 to Balance Growth with Carbon Availability in Arabidopsis.
    Curr. Biol., 2016. 26(14): p. 1854-60
  19. Zhang Y, et al.
    Functional characterization of GmBZL2 (AtBZR1 like gene) reveals the conserved BR signaling regulation in Glycine max.
    Sci Rep, 2016. 6: p. 31134
  20. Favero DS,Le KN,Neff MM
    Brassinosteroid signaling converges with SUPPRESSOR OF PHYTOCHROME B4-#3 to influence the expression of SMALL AUXIN UP RNA genes and hypocotyl growth.
    Plant J., 2017. 89(6): p. 1133-1145
  21. Li H, et al.
    BZR1 Positively Regulates Freezing Tolerance via CBF-Dependent and CBF-Independent Pathways in Arabidopsis.
    Mol Plant, 2017. 10(4): p. 545-559
  22. Zentella R, et al.
    The Arabidopsis O-fucosyltransferase SPINDLY activates nuclear growth repressor DELLA.
    Nat. Chem. Biol., 2017. 13(5): p. 479-485
  23. Espinosa-Ruiz A, et al.
    TOPLESS mediates brassinosteroid control of shoot boundaries and root meristem development in Arabidopsis thaliana.
    Development, 2017. 144(9): p. 1619-1628
  24. Li QF, et al.
    Light involved regulation of BZR1 stability and phosphorylation status to coordinate plant growth in Arabidopsis.
    Biosci. Rep., 2018.
  25. Thussagunpanit J, et al.
    Characterization of synthetic ecdysteroid analogues as functional mimics of brassinosteroids in plant growth.
    J. Steroid Biochem. Mol. Biol., 2017. 172: p. 1-8
  26. Zhu JY, et al.
    The F-box Protein KIB1 Mediates Brassinosteroid-Induced Inactivation and Degradation of GSK3-like Kinases in Arabidopsis.
    Mol. Cell, 2017. 66(5): p. 648-657.e4
  27. Yang M,Wang X
    Multiple Ways of BES1/BZR1 Degradation to Decode Distinct Developmental and Environmental Cues in Plants.
    Mol Plant, 2017. 10(7): p. 915-917
  28. Lv B, et al.
    Brassinosteroids regulate root growth by controlling reactive oxygen species homeostasis and dual effect on ethylene synthesis in Arabidopsis.
    PLoS Genet., 2018. 14(1): p. e1007144
  29. IbaƱez C, et al.
    Brassinosteroids Dominate Hormonal Regulation of Plant Thermomorphogenesis via BZR1.
    Curr. Biol., 2018. 28(2): p. 303-310.e3
  30. Saito M,Kondo Y,Fukuda H
    BES1 and BZR1 Redundantly Promote Phloem and Xylem Differentiation.
    Plant Cell Physiol., 2018. 59(3): p. 590-600
  31. Li QF, et al.
    The brassinosteroid-regulated transcription factors BZR1/BES1 function as a coordinator in multisignal-regulated plant growth.
    Biochim Biophys Acta Gene Regul Mech, 2018. 1861(6): p. 561-571
  32. Nosaki S, et al.
    Structural basis for brassinosteroid response by BIL1/BZR1.
    Nat Plants, 2018. 4(10): p. 771-776