PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID cra_locus_8075_iso_4
Organism
Catharanthus roseus
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Gentianales; Apocynaceae; Rauvolfioideae; Vinceae; Catharanthinae; Catharanthus
Family MYB
Protein Properties Length: 519aa    MW: 57626.6 Da    PI: 5.6917
Description MYB family protein
Gene Model
Gene Model ID Type Source Coding Sequence
cra_locus_8075_iso_4genomeMPGR-
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Myb_DNA-binding44.43.8e-143175348
                                         SS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS
                      Myb_DNA-binding  3 rWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48
                                         +W++eEd++l + ++ +G+++W+ Ia+++   +t  qc+ rw++yl
  cra_locus_8075_iso_4_len_2769_ver_3 31 SWSQEEDDILREQIRIHGTENWAIIASKFK-DKTTRQCRRRWFTYL 75
                                         6****************************9.*************97 PP
2Myb_DNA-binding43.38.6e-1481124146
                                          TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHH CS
                      Myb_DNA-binding   1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqk 46 
                                          rg W++eEd ll +a k +G++ W+ Ia+ +  gRt++ +k+r+ +
  cra_locus_8075_iso_4_len_2769_ver_3  81 RGGWSPEEDMLLCEAQKVFGNR-WTEIAKVVS-GRTDNAVKNRFTT 124
                                          789*******************.*********.**********976 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5129415.5672475IPR017930Myb domain
SMARTSM007176.0E-132877IPR001005SANT/Myb domain
SuperFamilySSF466891.16E-2529122IPR009057Homeodomain-like
CDDcd001677.22E-133175No hitNo description
PfamPF139212.6E-143292No hitNo description
Gene3DG3DSA:1.10.10.602.1E-203282IPR009057Homeodomain-like
PROSITE profilePS5129419.94576130IPR017930Myb domain
SMARTSM007171.2E-1480128IPR001005SANT/Myb domain
Gene3DG3DSA:1.10.10.601.4E-1983129IPR009057Homeodomain-like
CDDcd001675.16E-1184125No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0009553Biological Processembryo sac development
GO:0010052Biological Processguard cell differentiation
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 519 aa     Download sequence    Send to blast
MQSVVKKKAT TSSDGNSGQQ VPKQKERHIV SWSQEEDDIL REQIRIHGTE NWAIIASKFK  60
DKTTRQCRRR WFTYLNSDFK RGGWSPEEDM LLCEAQKVFG NRWTEIAKVV SGRTDNAVKN  120
RFTTLCKKRA KHEALAKENK NASFINLNNK RVIFPIGLNT DGTSEAAGPL KKRKQYCTKL  180
ELSCXNATRS KAYELTISSD LGGAXIPDPS ENGNHDEKLL GESGTATQSL RHPFAVLAQN  240
SHRTGSNLST QQNVNDIKET PVDGCNSKIQ GTFLKKDDPK ILALMQQAEL LSSLAAKVNS  300
ENTDQSLESA WKVLQDFLNQ PKESDEVSFR ISEMSFQLEN IKDLIEDLQG SNDCSRQSWR  360
QPDLYEESSA SSDYSTGSTL PSNAQSDKTE QIQSDISGQY PGIEPDLQPP HAGHLHGLAE  420
GEQEMSCDQT ADQDILPSCE EITTESLAAC GFSNADYSSP LHETPLFRTI AATIPSPKFS  480
ESEKHFLLRA LGMEPTPSDS SITNPSQPPT CKRALLQSL
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1a5j_A3e-263212910107B-MYB
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that binds to DNA in promoters cis-regulatory element 5'-GGCGCGC-3' of cell cycle genes, including cyclins, cyclin-dependent kinases (CDKs), and components of the pre-replication complex (PubMed:20675570, PubMed:24687979). Binds to DNA in promoters cis-regulatory element 5'-AGCCG-3' of auxin regulated genes (e.g. PIN3 and PIN7) (PubMed:26578169). Together with FAMA and MYB124, ensures that stomata contain just two guard cells (GCs) by enforcing a single symmetric precursor cell division before stomatal maturity (PubMed:24571519). Represses the expression of the mitosis-inducing factors CDKB1-1 and CDKA-1, specifically required for the last guard mother cells (GMC) symmetric divisions in the stomatal pathway (PubMed:20675570, PubMed:24687979). Represses CYCA2-3 in newly formed guard cells (PubMed:21772250). Together with MYB88, regulates stomata spacing by restricting divisions late in the stomatal cell lineage thus limiting the number of GMC divisions (PubMed:16155180). In collaboration with CDKB1-1 and CDKB1-2, restrict the G1/S transition and chloroplast and nuclear number during stomatal formation, and normally maintain fate and developmental progression throughout the stomatal cell lineage (PubMed:24123248). Involved in sensing and/or transducing abiotic stress (e.g. drought and salt), probably via the positive regulation of NAC019 (PubMed:21105921). Regulates female reproduction being required for entry into megasporogenesis, probably via the regulation of cell cycle genes (PubMed:22915737). Plays a minor role in lateral roots (LRs) initiation (PubMed:26578065). Involved complementarily in establishing the gravitropic set-point angles of lateral roots by regulating the transcription of PIN3 and PIN7 in gravity-sensing cells of primary and lateral roots (PubMed:26578169). {ECO:0000269|PubMed:16155180, ECO:0000269|PubMed:20675570, ECO:0000269|PubMed:21105921, ECO:0000269|PubMed:21772250, ECO:0000269|PubMed:22915737, ECO:0000269|PubMed:24123248, ECO:0000269|PubMed:24571519, ECO:0000269|PubMed:24687979, ECO:0000269|PubMed:26578065, ECO:0000269|PubMed:26578169}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00259DAPTransfer from AT2G02820Download
Motif logo
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_027154324.10.0transcription factor MYB124
SwissprotF4IRB41e-157MYB88_ARATH; Transcription factor MYB88
TrEMBLA0A068TVN30.0A0A068TVN3_COFCA; Uncharacterized protein
STRINGSolyc05g007160.2.10.0(Solanum lycopersicum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA41242134
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  3. Yang K, et al.
    Requirement for A-type cyclin-dependent kinase and cyclins for the terminal division in the stomatal lineage of Arabidopsis.
    J. Exp. Bot., 2014. 65(9): p. 2449-61
    [PMID:24687979]
  4. Yang M
    The FOUR LIPS (FLP) and MYB88 genes conditionally suppress the production of nonstomatal epidermal cells in Arabidopsis cotyledons.
    Am. J. Bot., 2016. 103(9): p. 1559-66
    [PMID:27620181]
  5. Xu Z, et al.
    DGE-seq analysis of MUR3-related Arabidopsis mutants provides insight into how dysfunctional xyloglucan affects cell elongation.
    Plant Sci., 2017. 258: p. 156-169
    [PMID:28330559]
  6. Qu Y, et al.
    Peroxisomal CuAOζ and its product H2O2 regulate the distribution of auxin and IBA-dependent lateral root development in Arabidopsis.
    J. Exp. Bot., 2017. 68(17): p. 4851-4867
    [PMID:28992128]
  7. Xie Y, et al.
    An atypical R2R3 MYB transcription factor increases cold hardiness by CBF-dependent and CBF-independent pathways in apple.
    New Phytol., 2018. 218(1): p. 201-218
    [PMID:29266327]