PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MELO3C013835P1
Organism
Cucumis melo
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis
Family HSF
Protein Properties Length: 519aa    MW: 56738 Da    PI: 4.7
Description HSF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MELO3C013835P1genomeMELONOMICSView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HSF_DNA-bind114.47.5e-36361272102
                     HHHHHHHHHCTGGGTTTSEESSSSSEEEES-HHHHHHHTHHHHSTT--HHHHHHHHHHTTEEE---SSBTTTTXTTSEEEEESXXXXXXXXXXXX CS
    HSF_DNA-bind   2 FlkklyeiledeelkeliswsengnsfvvldeeefakkvLpkyFkhsnfaSFvRQLnmYgFkkvkdeekkskskekiweFkhksFkkgkkellek 96 
                     Fl+k+y++++d++++ ++sws ++nsfvv+++ efa+++LpkyFkh+nf+SFvRQLn+YgF+kv+ ++         weF+++ F +g+k+ll++
  MELO3C013835P1  36 FLSKTYDMVDDPATDAVVSWSPTNNSFVVWNPPEFARDLLPKYFKHNNFSSFVRQLNTYGFRKVDPDR---------WEFANEGFLRGQKHLLKS 121
                     9********************999*****************************************999.........****************** PP

                     XXXXXX CS
    HSF_DNA-bind  97 ikrkks 102
                     i r+k 
  MELO3C013835P1 122 ITRRKP 127
                     ***985 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.104.3E-4029120IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM004152.5E-6432125IPR000232Heat shock factor (HSF)-type, DNA-binding
SuperFamilySSF467853.94E-3632125IPR011991Winged helix-turn-helix DNA-binding domain
PRINTSPR000561.4E-203659IPR000232Heat shock factor (HSF)-type, DNA-binding
PfamPF004472.0E-3236125IPR000232Heat shock factor (HSF)-type, DNA-binding
PRINTSPR000561.4E-207486IPR000232Heat shock factor (HSF)-type, DNA-binding
PROSITE patternPS0043407599IPR000232Heat shock factor (HSF)-type, DNA-binding
PRINTSPR000561.4E-208799IPR000232Heat shock factor (HSF)-type, DNA-binding
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009408Biological Processresponse to heat
GO:0005634Cellular Componentnucleus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 519 aa     Download sequence    Send to blast
MDGTANGGDS GLASGSGNSH PTVPAPITNS NAPPPFLSKT YDMVDDPATD AVVSWSPTNN  60
SFVVWNPPEF ARDLLPKYFK HNNFSSFVRQ LNTYGFRKVD PDRWEFANEG FLRGQKHLLK  120
SITRRKPVHG QSQQQPQQSH GQSSSVGACV EVGKFGLEEE VERLKRDKNV LMQELVRLRQ  180
QQQTTDNQLQ TMVQRLQGME QRQQQMMSFL AKAVQSPGFL AQFVQQQNES TRRISEANKK  240
RRLKQDGIGE SEHSPVPDGQ IVKYQPLMNE AAKTMLRQIM KVDTSHLDSL NNNTDSFLIG  300
DGLQSPCTAM DNGNSSSSVS GVTLQEVPPT SSFNSAASGA PHGPSTAKSE IQSSPQATNS  360
DKVSAASFAL NAVRGPGARE ASSLSVSETD VIMPELSHLS EMVSENILDV PEVDYRVPEA  420
GDGAFISPNF LDANGTIPID IDNMSPDADI DALLDNSNFW DDLLVESPCQ DEEVDFMVGG  480
GLPKTNDMQP AENAWDKSKH VDKLTEQMGL LTSEIKRV*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5d5u_B5e-29101255129Heat shock factor protein 1
5d5v_B5e-29101255129Heat shock factor protein 1
5d5v_D5e-29101255129Heat shock factor protein 1
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1237244NKKRRLKQ
2238243KKRRLK
Functional Description ? help Back to Top
Source Description
UniProtDNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. {ECO:0000250}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankLN6818600.0LN681860.1 Cucumis melo genomic scaffold, anchoredscaffold00021.
GenBankLN7132600.0LN713260.1 Cucumis melo genomic chromosome, chr_6.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_008448660.10.0PREDICTED: heat shock factor protein HSF8-like
SwissprotQ401521e-177HSF8_SOLLC; Heat shock factor protein HSF8
TrEMBLA0A1S3BL380.0A0A1S3BL38_CUCME; heat shock factor protein HSF8-like
STRINGXP_008448660.10.0(Cucumis melo)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF18433169
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G32330.11e-135heat shock transcription factor A1D
Publications ? help Back to Top
  1. Zhu B, et al.
    Identification and characterization of a novel heat shock transcription factor gene, GmHsfA1, in soybeans (Glycine max).
    J. Plant Res., 2006. 119(3): p. 247-56
    [PMID:16570125]
  2. Cai SY, et al.
    HsfA1a upregulates melatonin biosynthesis to confer cadmium tolerance in tomato plants.
    J. Pineal Res., 2017.
    [PMID:28095626]
  3. Zhou J, et al.
    Heat Shock Factor HsfA1a Is Essential for R Gene-Mediated Nematode Resistance and Triggers H2O2 Production1.
    Plant Physiol., 2018. 176(3): p. 2456-2471
    [PMID:29339397]