PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

AT5G65510.1

Common Name

AIL7, K21L13.1, PLT7

Organism

Arabidopsis thaliana

Taxonomic ID

3702

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis

Family

AP2

Protein Properties

Length: 498aa MW: 55448.1 Da PI: 6.5127

Description

AINTEGUMENTA-like 7

Gene Model

Gene Model ID	Type	Source	Coding Sequence
AT5G65510.1	genome	TAIR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	43.3	9e-14	230	289	1	55
AP2 1 sgykGVrwdkkrgrWvAeIrd.pse.ng..kr.krfslgkfgtaeeAakaaiaarkkleg 55 s y+GV++++++gr++A+++d + g ++ ++++lg ++ ++ Aa+a++ a++k++g AT5G65510.1 230 SIYRGVTRHRWTGRYEAHLWDnSCRrEGqaRKgRQVYLGGYDKEDRAARAYDLAALKYWG 289 57*****************666664478446******99***********98 PP
2	AP2	49.9	7.8e-16	332	383	1	55
AP2 1 sgykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 s y+GV++++++grW A+I + +k +lg+f t+eeAa+a++ a+ k++g AT5G65510.1 332 SIYRGVTRHHQQGRWQARIGRVAG---NKDLYLGTFATEEEAAEAYDIAAIKFRG 383 57**************988532...5**********************997 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF54171	8.5E-17	230	299	IPR016177	DNA-binding domain
Pfam	PF00847	7.4E-11	230	289	IPR001471	AP2/ERF domain
CDD	cd00018	1.68E-22	230	299	No hit	No description
PROSITE profile	PS51032	18.993	231	297	IPR001471	AP2/ERF domain
Gene3D	G3DSA:3.30.730.10	2.0E-15	231	298	IPR001471	AP2/ERF domain
SMART	SM00380	2.1E-28	231	303	IPR001471	AP2/ERF domain
PRINTS	PR00367	4.0E-6	232	243	IPR001471	AP2/ERF domain
CDD	cd00018	1.66E-11	332	391	No hit	No description
Pfam	PF00847	3.3E-10	332	383	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	8.5E-18	332	392	IPR016177	DNA-binding domain
Gene3D	G3DSA:3.30.730.10	4.4E-18	333	391	IPR001471	AP2/ERF domain
PROSITE profile	PS51032	19.111	333	391	IPR001471	AP2/ERF domain
SMART	SM00380	6.3E-30	333	397	IPR001471	AP2/ERF domain
PRINTS	PR00367	4.0E-6	373	393	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0009873	Biological Process	ethylene-activated signaling pathway
GO:0010492	Biological Process	maintenance of shoot apical meristem identity
GO:0060772	Biological Process	leaf phyllotactic patterning
GO:0060774	Biological Process	auxin mediated signaling pathway involved in phyllotactic patterning
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Plant Ontology ? help Back to Top
PO Term	PO Category	PO Description
PO:0000037	anatomy	shoot apex
PO:0009009	anatomy	plant embryo
PO:0009010	anatomy	seed
PO:0009046	anatomy	flower
PO:0020100	anatomy	hypocotyl
PO:0025022	anatomy	collective leaf structure
PO:0001078	developmental stage	plant embryo cotyledonary stage
PO:0001081	developmental stage	mature plant embryo stage
PO:0004507	developmental stage	plant embryo bilateral stage
PO:0007611	developmental stage	petal differentiation and expansion stage

Sequence ? help Back to Top
Protein Sequence Length: 498 aa Download sequence Send to blast
MAPPMTNCLT FSLSPMEMLK STDQSHFSSS YDDSSTPYLI DNFYAFKEEA EIEAAAASMA 60 DSTTLSTFFD HSQTQIPKLE DFLGDSFVRY SDNQTETQDS SSLTPFYDPR HRTVAEGVTG 120 FFSDHHQPDF KTINSGPEIF DDSTTSNIGG THLSSHVVES STTAKLGFNG DCTTTGGVLS 180 LGVNNTSDQP LSCNNGERGG NSNKKKTVSK KETSDDSKKK IVETLGQRTS IYRGVTRHRW 240 TGRYEAHLWD NSCRREGQAR KGRQVYLGGY DKEDRAARAY DLAALKYWGS TATTNFPVSS 300 YSKELEEMNH MTKQEFIASL RRKSSGFSRG ASIYRGVTRH HQQGRWQARI GRVAGNKDLY 360 LGTFATEEEA AEAYDIAAIK FRGINAVTNF EMNRYDIEAV MNSSLPVGGA AAKRHKLKLA 420 LESPSSSSSD HNLQQQQLLP SSSPSDQNPN SIPCGIPFEP SVLYYHQNFF QHYPLVSDST 480 IQAPMNQAEF FLWPNQSY

Sequence ? help Back to Top

Protein Sequence Length: 498 aa Download sequence Send to blast

MAPPMTNCLT FSLSPMEMLK STDQSHFSSS YDDSSTPYLI DNFYAFKEEA EIEAAAASMA  60
DSTTLSTFFD HSQTQIPKLE DFLGDSFVRY SDNQTETQDS SSLTPFYDPR HRTVAEGVTG  120
FFSDHHQPDF KTINSGPEIF DDSTTSNIGG THLSSHVVES STTAKLGFNG DCTTTGGVLS  180
LGVNNTSDQP LSCNNGERGG NSNKKKTVSK KETSDDSKKK IVETLGQRTS IYRGVTRHRW  240
TGRYEAHLWD NSCRREGQAR KGRQVYLGGY DKEDRAARAY DLAALKYWGS TATTNFPVSS  300
YSKELEEMNH MTKQEFIASL RRKSSGFSRG ASIYRGVTRH HQQGRWQARI GRVAGNKDLY  360
LGTFATEEEA AEAYDIAAIK FRGINAVTNF EMNRYDIEAV MNSSLPVGGA AAKRHKLKLA  420
LESPSSSSSD HNLQQQQLLP SSSPSDQNPN SIPCGIPFEP SVLYYHQNFF QHYPLVSDST  480
IQAPMNQAEF FLWPNQSY

Expression -- Microarray ? help Back to Top
Source	ID	E-value
GEO	240256482	0.0
Genevisible	247196_at	0.0
Expression Atlas	AT5G65510	-
AtGenExpress	AT5G65510	-
ATTED-II	AT5G65510	-

Expression -- Description ? help Back to Top
Source	Description
Uniprot	DEVELOPMENTAL STAGE: Confined to the central region of inflorescence ane floral meristems, progressively restricted to the innermost cells of the dome. Also detected in developing stamen locules and later in sporogonous cells within locules. In carpel primordia, found in placenta and in young ovule primordia. {ECO:0000269\|PubMed:15988559}.
Uniprot	TISSUE SPECIFICITY: Expressed in roots, seedlings, inflorescence, and siliques. Also detected at low levels in leaves. {ECO:0000269\|PubMed:15988559}.

Functional Description ? help Back to Top
Source	Description
UniProt	Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity). {ECO:0000250}.

Function -- GeneRIF ? help Back to Top
PLT proteins are key regulators of PIN1 activity in control of phyllotaxis. PLT3, PLT5, and PLT7 are essential for normal phyllotaxis. [PLT7] [PMID: 21700457] ANT, AIL6 and AIL7 are expressed in distinct domains within the vegetative shoot apical meristem. Triple mutant shoot apical meristems exhibit morphological and cell division defects. [PMID: 22380923] In A. thaliana, three transcriptional regulators implicated in phyllotaxis, PLETHORA3 (PLT3), PLT5, and PLT7, are expressed in incipient lateral root primordia where they are required for primordium development and lateral root emergence.[PLT7] [PMID: 23684976] AIL genes exhibit unequal genetic redundancy with roles for AIL5, AIL6, and AIL7 only revealed in the absence of ANT function. AIL5, AIL6, and AIL7 act in a dose dependent manners in ant and other mutant backgrounds. [PMID: 25956884] This study characterized the effects of three PLETHORA (PLT) transcription factors, PLT3, PLT5, and PLT7, during lateral root outgrowth. [PMID: 29078398]

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00589	DAP	27203113	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	AT5G65510.1

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Phenotype -- Mutation ? help Back to Top
Source	ID
T-DNA Express	AT5G65510

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AY560887	0.0	AY560887.1 Arabidopsis thaliana putative AP2/EREBP transcription factor (At5g65510) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	NP_001318882.1	0.0	AINTEGUMENTA-like 7
Refseq	NP_201354.5	0.0	AINTEGUMENTA-like 7
Swissprot	Q6J9N8	0.0	AIL7_ARATH; AP2-like ethylene-responsive transcription factor AIL7
TrEMBL	A0A1P8BA69	0.0	A0A1P8BA69_ARATH; AINTEGUMENTA-like 7
STRING	AT5G65510.1	0.0	(Arabidopsis thaliana)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM3333	27	65
Representative plant	OGRP112	17	209

Link Out ? help Back to Top
Phytozome	AT5G65510.1
Entrez Gene	836677
iHOP	AT5G65510
wikigenes	AT5G65510

Publications ? help Back to Top
Todd J,Post-Beittenmiller D,Jaworski JG KCS1 encodes a fatty acid elongase 3-ketoacyl-CoA synthase affecting wax biosynthesis in Arabidopsis thaliana. Plant J., 1999. 17(2): p. 119-30 [PMID:10074711] Krizek BA,Prost V,Macias A AINTEGUMENTA promotes petal identity and acts as a negative regulator of AGAMOUS. Plant Cell, 2000. 12(8): p. 1357-66 [PMID:10948255] Riechmann JL, et al. Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes. Science, 2000. 290(5499): p. 2105-10 [PMID:11118137] Nole-Wilson S,Tranby TL,Krizek BA AINTEGUMENTA-like (AIL) genes are expressed in young tissues and may specify meristematic or division-competent states. Plant Mol. Biol., 2005. 57(5): p. 613-28 [PMID:15988559] Kim S,Soltis PS,Wall K,Soltis DE Phylogeny and domain evolution in the APETALA2-like gene family. Mol. Biol. Evol., 2006. 23(1): p. 107-20 [PMID:16151182] Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Nakano T,Suzuki K,Fujimura T,Shinshi H Genome-wide analysis of the ERF gene family in Arabidopsis and rice. Plant Physiol., 2006. 140(2): p. 411-32 [PMID:16407444] Che P,Lall S,Nettleton D,Howell SH Gene expression programs during shoot, root, and callus development in Arabidopsis tissue culture. Plant Physiol., 2006. 141(2): p. 620-37 [PMID:16648215] Prasad K, et al. Arabidopsis PLETHORA transcription factors control phyllotaxis. Curr. Biol., 2011. 21(13): p. 1123-8 [PMID:21700457] Mudunkothge JS,Krizek BA Three Arabidopsis AIL/PLT genes act in combination to regulate shoot apical meristem function. Plant J., 2012. 71(1): p. 108-21 [PMID:22380923] Pinon V,Prasad K,Grigg SP,Sanchez-Perez GF,Scheres B Local auxin biosynthesis regulation by PLETHORA transcription factors controls phyllotaxis in Arabidopsis. Proc. Natl. Acad. Sci. U.S.A., 2013. 110(3): p. 1107-12 [PMID:23277580] Hofhuis H, et al. Phyllotaxis and rhizotaxis in Arabidopsis are modified by three PLETHORA transcription factors. Curr. Biol., 2013. 23(11): p. 956-62 [PMID:23684976] Krizek BA AINTEGUMENTA-LIKE genes have partly overlapping functions with AINTEGUMENTA but make distinct contributions to Arabidopsis thaliana flower development. J. Exp. Bot., 2015. 66(15): p. 4537-49 [PMID:25956884] Santuari L, et al. The PLETHORA Gene Regulatory Network Guides Growth and Cell Differentiation in Arabidopsis Roots. Plant Cell, 2016. 28(12): p. 2937-2951 [PMID:27920338] Du Y,Scheres B PLETHORA transcription factors orchestrate de novo organ patterning during Arabidopsis lateral root outgrowth. Proc. Natl. Acad. Sci. U.S.A., 2017. 114(44): p. 11709-11714 [PMID:29078398] Elliott RC, et al. AINTEGUMENTA, an APETALA2-like gene of Arabidopsis with pleiotropic roles in ovule development and floral organ growth. Plant Cell, 1996. 8(2): p. 155-68 [PMID:8742707] Okamuro JK,Caster B,Villarroel R,Van Montagu M,Jofuku KD The AP2 domain of APETALA2 defines a large new family of DNA binding proteins in Arabidopsis. Proc. Natl. Acad. Sci. U.S.A., 1997. 94(13): p. 7076-81 [PMID:9192694]