PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT5G11190.1
Common NameERF004, F2I11.80, SHN2
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family ERF
Protein Properties Length: 189aa    MW: 21409.3 Da    PI: 6.1391
Description ERF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
AT5G11190.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
          AP2  2 gykGVrwdkkrgrWvAeIrdpsengkr..krfslgkfgtaeeAakaaiaarkkleg 55
                 +++GVr++  +g+Wv+eIr+p        +r++lg+f tae Aa+a+++a++ ++g
                 89****999.**********8.....334**********************98877 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:3.30.730.101.8E-32564IPR001471AP2/ERF domain
CDDcd000188.82E-23665No hitNo description
PfamPF008471.2E-11655IPR001471AP2/ERF domain
SMARTSM003803.0E-39669IPR001471AP2/ERF domain
SuperFamilySSF541715.89E-20664IPR016177DNA-binding domain
PROSITE profilePS5103222.221663IPR001471AP2/ERF domain
PRINTSPR003672.9E-10718IPR001471AP2/ERF domain
PRINTSPR003672.9E-102945IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009873Biological Processethylene-activated signaling pathway
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000293anatomyguard cell
PO:0004707anatomyfruit dehiscence zone
PO:0005011anatomyanther dehiscence zone
Sequence ? help Back to Top
Protein Sequence    Length: 189 aa     Download sequence    Send to blast
3D Structure ? help Back to Top
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5wx9_A1e-166631472Ethylene-responsive transcription factor ERF096
Search in ModeBase
Expression -- Microarray ? help Back to Top
Source ID E-value
Expression AtlasAT5G11190-
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: The SHN2 gene shows a pattern of expression associated with anther and silique dehiscence. Expressed in the stomium region when tapetum degeneration is initiated in the anther. Up to anthesis and until stamens fell off the senescing flower, restricted to the anther dehiscence zone. Subsequently, when petals and sepals withered, found at the bottom of each valve. During silique development, strongly expressed along the valve margin-replum boundary. {ECO:0000269|PubMed:15319479}.
UniprotTISSUE SPECIFICITY: In flowers. {ECO:0000269|PubMed:15319479}.
Functional Description ? help Back to Top
Source Description
TAIRencodes a member of the ERF (ethylene response factor) subfamily B-6 of ERF/AP2 transcription factor family. The protein contains one AP2 domain. There are 12 members in this subfamily including RAP2.11.
UniProtPromotes cuticle formation by inducing the expression of enzymes involved in wax biosynthesis. Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity). {ECO:0000250, ECO:0000269|PubMed:15319479}.
Function -- GeneRIF ? help Back to Top
  1. Silencing SHINE clade genes (SHN1/SHN2/SHN3) reduces flower cutin load and modifies petal cell wall structure.
    [PMID: 21637781]
Cis-element ? help Back to Top
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT5G11190
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAY5608650.0AY560865.1 Arabidopsis thaliana putative AP2/EREBP transcription factor (At5g11190) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_196680.11e-138Integrase-type DNA-binding superfamily protein
SwissprotQ9LFN71e-139SHN2_ARATH; Ethylene-responsive transcription factor SHINE 2
STRINGAT5G11190.11e-137(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
Representative plantOGRP6161718
Publications ? help Back to Top
  1. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
  2. Broun P,Poindexter P,Osborne E,Jiang CZ,Riechmann JL
    WIN1, a transcriptional activator of epidermal wax accumulation in Arabidopsis.
    Proc. Natl. Acad. Sci. U.S.A., 2004. 101(13): p. 4706-11
  3. Czechowski T,Bari RP,Stitt M,Scheible WR,Udvardi MK
    Real-time RT-PCR profiling of over 1400 Arabidopsis transcription factors: unprecedented sensitivity reveals novel root- and shoot-specific genes.
    Plant J., 2004. 38(2): p. 366-79
  4. Aharoni A, et al.
    The SHINE clade of AP2 domain transcription factors activates wax biosynthesis, alters cuticle properties, and confers drought tolerance when overexpressed in Arabidopsis.
    Plant Cell, 2004. 16(9): p. 2463-80
  5. Nakano T,Suzuki K,Fujimura T,Shinshi H
    Genome-wide analysis of the ERF gene family in Arabidopsis and rice.
    Plant Physiol., 2006. 140(2): p. 411-32
  6. Shi JX, et al.
    SHINE transcription factors act redundantly to pattern the archetypal surface of Arabidopsis flower organs.
    PLoS Genet., 2011. 7(5): p. e1001388
  7. Lisso J,Schr
    NFXL2 modifies cuticle properties in Arabidopsis.
    Plant Signal Behav, 2012. 7(5): p. 551-5
  8. Efroni I, et al.
    Regulation of leaf maturation by chromatin-mediated modulation of cytokinin responses.
    Dev. Cell, 2013. 24(4): p. 438-45
  9. Li-Beisson Y, et al.
    Acyl-lipid metabolism.
    Arabidopsis Book, 2013. 11: p. e0161
  10. Djemal R,Khoudi H
    Isolation and molecular characterization of a novel WIN1/SHN1 ethylene-responsive transcription factor TdSHN1 from durum wheat (Triticum turgidum. L. subsp. durum).
    Protoplasma, 2015. 252(6): p. 1461-73
  11. Liu Y, et al.
    Functional Characterization of Populus PsnSHN2 in Coordinated Regulation of Secondary Wall Components in Tobacco.
    Sci Rep, 2017. 7(1): p. 42
  12. Kumar V, et al.
    A part of the upstream promoter region of SHN2 gene directs trichome specific expression in Arabidopsis thaliana and heterologous plants.
    Plant Sci., 2017. 264: p. 138-148