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PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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| Home TFext BLAST Prediction Download Help About Links PlantRegMap |
Transcription Factor Information
| Basic Information? help Back to Top | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| TF ID | AT2G02820.2 | ||||||||
| Common Name | AtMYB88, MYB88 | ||||||||
| Organism | |||||||||
| Taxonomic ID | |||||||||
| Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
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| Family | MYB | ||||||||
| Protein Properties | Length: 484aa MW: 54507.6 Da PI: 6.452 | ||||||||
| Description | myb domain protein 88 | ||||||||
| Gene Model |
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| Signature Domain? help Back to Top | |||||||
|---|---|---|---|---|---|---|---|
| No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
| 1 | Myb_DNA-binding | 40.6 | 5.9e-13 | 32 | 76 | 3 | 48 |
SS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS
Myb_DNA-binding 3 rWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48
W++eEd++l + + + G+++W+ Ia++++ ++ qc+ rw++yl
AT2G02820.2 32 TWSPEEDDILRKQISLQGTENWAIIASKFN-DKSTRQCRRRWYTYL 76
6*****************************.*************97 PP
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| 2 | Myb_DNA-binding | 44.7 | 3.1e-14 | 82 | 125 | 1 | 46 |
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHH CS
Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqk 46
rg W++eEd ll +a +++G++ W+ Ia+ + gRt++ +k+r+ +
AT2G02820.2 82 RGGWSPEEDTLLCEAQRLFGNR-WTEIAKVVS-GRTDNAVKNRFTT 125
789*******************.*********.**********976 PP
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| Protein Features ? help Back to Top | ||||||
|---|---|---|---|---|---|---|
| Database | Entry ID | E-value | Start | End | InterPro ID | Description |
| PROSITE profile | PS51294 | 14.001 | 25 | 76 | IPR017930 | Myb domain |
| SuperFamily | SSF46689 | 1.05E-24 | 29 | 123 | IPR009057 | Homeodomain-like |
| SMART | SM00717 | 2.0E-12 | 29 | 78 | IPR001005 | SANT/Myb domain |
| CDD | cd00167 | 1.10E-11 | 32 | 76 | No hit | No description |
| Pfam | PF13921 | 1.6E-15 | 33 | 93 | No hit | No description |
| Gene3D | G3DSA:1.10.10.60 | 2.3E-19 | 33 | 84 | IPR009057 | Homeodomain-like |
| PROSITE profile | PS51294 | 20.812 | 77 | 131 | IPR017930 | Myb domain |
| SMART | SM00717 | 8.4E-15 | 81 | 129 | IPR001005 | SANT/Myb domain |
| CDD | cd00167 | 1.09E-10 | 85 | 126 | No hit | No description |
| Gene3D | G3DSA:1.10.10.60 | 7.5E-19 | 85 | 130 | IPR009057 | Homeodomain-like |
| Gene Ontology ? help Back to Top | ||||||
|---|---|---|---|---|---|---|
| GO Term | GO Category | GO Description | ||||
| GO:0006357 | Biological Process | regulation of transcription from RNA polymerase II promoter | ||||
| GO:0009553 | Biological Process | embryo sac development | ||||
| GO:0010052 | Biological Process | guard cell differentiation | ||||
| GO:0005634 | Cellular Component | nucleus | ||||
| GO:0000981 | Molecular Function | RNA polymerase II transcription factor activity, sequence-specific DNA binding | ||||
| GO:0001135 | Molecular Function | transcription factor activity, RNA polymerase II transcription factor recruiting | ||||
| GO:0043565 | Molecular Function | sequence-specific DNA binding | ||||
| GO:0044212 | Molecular Function | transcription regulatory region DNA binding | ||||
| Plant Ontology ? help Back to Top | ||||||
|---|---|---|---|---|---|---|
| PO Term | PO Category | PO Description | ||||
| PO:0000013 | anatomy | cauline leaf | ||||
| PO:0000037 | anatomy | shoot apex | ||||
| PO:0000084 | anatomy | plant sperm cell | ||||
| PO:0000230 | anatomy | inflorescence meristem | ||||
| PO:0000293 | anatomy | guard cell | ||||
| PO:0009005 | anatomy | root | ||||
| PO:0009006 | anatomy | shoot system | ||||
| PO:0009009 | anatomy | plant embryo | ||||
| PO:0009010 | anatomy | seed | ||||
| PO:0009025 | anatomy | vascular leaf | ||||
| PO:0009046 | anatomy | flower | ||||
| PO:0009047 | anatomy | stem | ||||
| PO:0009052 | anatomy | flower pedicel | ||||
| PO:0020030 | anatomy | cotyledon | ||||
| PO:0020137 | anatomy | leaf apex | ||||
| PO:0025022 | anatomy | collective leaf structure | ||||
| PO:0001054 | developmental stage | vascular leaf senescent stage | ||||
| PO:0001078 | developmental stage | plant embryo cotyledonary stage | ||||
| PO:0001081 | developmental stage | mature plant embryo stage | ||||
| PO:0004507 | developmental stage | plant embryo bilateral stage | ||||
| PO:0007095 | developmental stage | LP.08 eight leaves visible stage | ||||
| PO:0007098 | developmental stage | LP.02 two leaves visible stage | ||||
| PO:0007103 | developmental stage | LP.10 ten leaves visible stage | ||||
| PO:0007115 | developmental stage | LP.04 four leaves visible stage | ||||
| PO:0007123 | developmental stage | LP.06 six leaves visible stage | ||||
| PO:0007611 | developmental stage | petal differentiation and expansion stage | ||||
| PO:0007616 | developmental stage | flowering stage | ||||
| Sequence ? help Back to Top |
|---|
| Protein Sequence Length: 484 aa Download sequence Send to blast |
MEETTKQNNM KKKKKILLHS DDSKKKERHI VTWSPEEDDI LRKQISLQGT ENWAIIASKF 60 NDKSTRQCRR RWYTYLNSDF KRGGWSPEED TLLCEAQRLF GNRWTEIAKV VSGRTDNAVK 120 NRFTTLCKKR AKHEAMAKEN RIACCVNSDN KRLLFPDGIS TPLKAESESP LTKKMRRSHI 180 PNLTEIKSYG DRSHIKVEST MNQQRRHPFS VVAHNATSSD GTEEQKQIGN VKESDGEDKS 240 NQEVFLKKDD SKVTALMQQA ELLSSLAQKV NADNTDQSME NAWKVLQDFL NKSKENDLFR 300 YGIPDIDFQL DEFKDLVEDL RSSNEDSQSS WRQPDLHDSP ASSEYSSGSG SGSTIMTHPS 360 GDKTQQLMSD TQTTSHQQNG GELLQDNGIV SDATVEQVGL LSTGHDVLKN SNETVPIPGE 420 EEFNSPVQVT PLFRSLAAGI PSPQFSESER NFLLKTLGVE SPSPYPSANP SQPPPCKRVL 480 LDSL |
| 3D Structure ? help Back to Top | ||||||
|---|---|---|---|---|---|---|
| PDB ID | Evalue | Query Start | Query End | Hit Start | Hit End | Description |
| 1a5j_A | 1e-23 | 33 | 131 | 10 | 108 | B-MYB |
| Search in ModeBase | ||||||
| Expression -- UniGene ? help Back to Top | ||||||
|---|---|---|---|---|---|---|
| UniGene ID | E-value | Expressed in | ||||
| At.11576 | 0.0 | flower| root | ||||
| Expression -- Microarray ? help Back to Top | ||||||
|---|---|---|---|---|---|---|
| Source | ID | E-value | ||||
| Genevisible | 267485_at | 0.0 | ||||
| Expression Atlas | AT2G02820 | - | ||||
| AtGenExpress | AT2G02820 | - | ||||
| ATTED-II | AT2G02820 | - | ||||
| Expression -- Description ? help Back to Top | ||||||
|---|---|---|---|---|---|---|
| Source | Description | |||||
| Uniprot | DEVELOPMENTAL STAGE: Accumulates during ovule development. Detected at low levels in ovules and in the embryo sac of stage 13 flowers (PubMed:22915737). Not detected during embryo development. In seedlings and young plants, present in some spots (presumably stomata) in cotyledons and later in veins of hypocotyls as well as of petioles, hydathodes, stipules, in roots and lateral root primordia, and in the lower halves of first leaves. Detected in the phloem, as well as in the cortex of inflorescence stems. In roots, confined in developing xylem cells in the part of the differentiation zone with well-developed root hairs (PubMed:26391711). Present in lateral root tips and subsequently in a larger area. Accumulates in columella cells of lateral roots (PubMed:26578169). Expressed at the base of developing flowers, including ovaries. In flowers, detected in parts of the major stem axis, and in the anther at some stages of development, present in veins of sepals and accumulates progressively in ovaries, filaments, receptacles, and ovules. Also detected in the valve margins and receptacles of siliques and at the joint between the stigma and the style, as well as in the tapetum around pollen grains in maturing anthers (PubMed:26391711). {ECO:0000269|PubMed:22915737, ECO:0000269|PubMed:26391711, ECO:0000269|PubMed:26578169}. | |||||
| Uniprot | TISSUE SPECIFICITY: Expressed at low levels in all organs including roots, leaves, hypocotyls stems, flowers, siliques and buds. {ECO:0000269|PubMed:16155180, ECO:0000269|PubMed:26391711}. | |||||
| Functional Description ? help Back to Top | ||||||
|---|---|---|---|---|---|---|
| Source | Description | |||||
| TAIR | Encodes a putative transcription factor (MYB88), involved in stomata development, double loss of MYB88 and FLP (MYB124) activity results in a failure of guard mother cells (GMCs) to adopt the guard cell fate, thus they continue to divide resulting in abnormal stomata consisting of clusters of numerous guard cell-like cells. This phenotype is enhanced in double mutants over the single mutant flp phenotype. | |||||
| UniProt | Transcription factor that binds to DNA in promoters cis-regulatory element 5'-GGCGCGC-3' of cell cycle genes, including cyclins, cyclin-dependent kinases (CDKs), and components of the pre-replication complex (PubMed:20675570, PubMed:24687979). Binds to DNA in promoters cis-regulatory element 5'-AGCCG-3' of auxin regulated genes (e.g. PIN3 and PIN7) (PubMed:26578169). Together with FAMA and MYB124, ensures that stomata contain just two guard cells (GCs) by enforcing a single symmetric precursor cell division before stomatal maturity (PubMed:24571519). Represses the expression of the mitosis-inducing factors CDKB1-1 and CDKA-1, specifically required for the last guard mother cells (GMC) symmetric divisions in the stomatal pathway (PubMed:20675570, PubMed:24687979). Represses CYCA2-3 in newly formed guard cells (PubMed:21772250). Together with MYB88, regulates stomata spacing by restricting divisions late in the stomatal cell lineage thus limiting the number of GMC divisions (PubMed:16155180). In collaboration with CDKB1-1 and CDKB1-2, restrict the G1/S transition and chloroplast and nuclear number during stomatal formation, and normally maintain fate and developmental progression throughout the stomatal cell lineage (PubMed:24123248). Involved in sensing and/or transducing abiotic stress (e.g. drought and salt), probably via the positive regulation of NAC019 (PubMed:21105921). Regulates female reproduction being required for entry into megasporogenesis, probably via the regulation of cell cycle genes (PubMed:22915737). Plays a minor role in lateral roots (LRs) initiation (PubMed:26578065). Involved complementarily in establishing the gravitropic set-point angles of lateral roots by regulating the transcription of PIN3 and PIN7 in gravity-sensing cells of primary and lateral roots (PubMed:26578169). {ECO:0000269|PubMed:16155180, ECO:0000269|PubMed:20675570, ECO:0000269|PubMed:21105921, ECO:0000269|PubMed:21772250, ECO:0000269|PubMed:22915737, ECO:0000269|PubMed:24123248, ECO:0000269|PubMed:24571519, ECO:0000269|PubMed:24687979, ECO:0000269|PubMed:26578065, ECO:0000269|PubMed:26578169}. | |||||
| Function -- GeneRIF ? help Back to Top | ||||||
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| Binding Motif ? help Back to Top | |||
|---|---|---|---|
| Motif ID | Method | Source | Motif file |
| MP00259 | DAP | 27203113 | Download |
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| Cis-element ? help Back to Top | |
|---|---|
| Source | Link |
| PlantRegMap | AT2G02820.2 |
| Regulation -- PlantRegMap ? help Back to Top | ||||||
|---|---|---|---|---|---|---|
| Source | Upstream Regulator | Target Gene | ||||
| PlantRegMap | Retrieve | Retrieve | ||||
| Regulation -- ATRM (Manually Curated Upstream Regulators) ? help Back to Top | ||||||
|---|---|---|---|---|---|---|
| Source | Upstream Regulator (A: Activate/R: Repress) | |||||
| ATRM | AT3G50410 (A) | |||||
| Phenotype -- Mutation ? help Back to Top | ||||||
|---|---|---|---|---|---|---|
| Source | ID | |||||
| T-DNA Express | AT2G02820 | |||||
| Annotation -- Nucleotide ? help Back to Top | ||||||
|---|---|---|---|---|---|---|
| Source | Hit ID | E-value | Description | |||
| GenBank | AK226575 | 0.0 | AK226575.1 Arabidopsis thaliana mRNA for hypothetical protein, clone: RAFL07-13-I18. | |||
| Annotation -- Protein ? help Back to Top | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-value | Description | ||||
| Refseq | NP_001030957.1 | 0.0 | myb domain protein 88 | ||||
| Swissprot | F4IRB4 | 0.0 | MYB88_ARATH; Transcription factor MYB88 | ||||
| TrEMBL | A0A178VPJ2 | 0.0 | A0A178VPJ2_ARATH; MYB88 | ||||
| STRING | AT2G02820.2 | 0.0 | (Arabidopsis thaliana) | ||||
| Orthologous Group ? help Back to Top | |||
|---|---|---|---|
| Lineage | Orthologous Group ID | Taxa Number | Gene Number |
| Malvids | OGEM3374 | 28 | 63 | Representative plant | OGRP5416 | 14 | 21 |
| Link Out ? help Back to Top | |
|---|---|
| Phytozome | AT2G02820.2 |
| Entrez Gene | 814812 |
| iHOP | AT2G02820 |
| wikigenes | AT2G02820 |
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