PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fagales; Fagaceae; Castanea

Family

NAC

Protein Properties

Length: 97aa MW: 10861.3 Da PI: 10.7392

Description

NAC family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
snap_masked-scaffold13705-abinit-gene-0.5-mRNA-1	genome	THGP	View Nucleic Acid

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	NAM	78.1	2e-24	11	88	51	127
NAM 51 vkaeekewyfFskrdkkyatgkrknratksgyWkatgkdkevlsk.kgelvglkktLvfyk 110 +k+++ ew+fFs+rd k+++++r+nrat+sg Wk tgkd++++++ +++++g+ ktLvfy snap_masked-scaffold13705-abinit-gene-0.5-mRNA-1 11 IKSDDPEWFFFSPRDFKNSNSNRRNRATQSGCWKVTGKDRKIKARgTNNVIGTMKTLVFYG 71 567888************************************967778******* PP NAM 111 grapkgektdWvmheyr 127 gr g++t+ vmhey+ snap_masked-scaffold13705-abinit-gene-0.5-mRNA-1 72 GRVGGGVRTNGVMHEYH 88 **************8 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51005	27.609	1	97	IPR003441	NAC domain
SuperFamily	SSF101941	2.09E-26	11	92	IPR003441	NAC domain
Pfam	PF02365	1.5E-13	15	88	IPR003441	NAC domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 97 aa Download sequence Send to blast
MLPGCAEFSV IKSDDPEWFF FSPRDFKNSN SNRRNRATQS GCWKVTGKDR KIKARGTNNV 60 IGTMKTLVFY GGRVGGGVRT NGVMHEYHPT VTLPHQA

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
3ulx_A	9e-18	17	87	70	138	Stress-induced transcription factor NAC1
Search in ModeBase

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	70	76	GGRVGGG

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional activator activated by proteolytic cleavage through regulated intramembrane proteolysis (RIP) (PubMed:18443413, PubMed:24329768). Calmodulin-regulated transcriptional repressor. Binds several synthetic promoters with randomly selected binding sites (PubMed:17947243). Functions synergistically with SNI1 as negative regulator of pathogen-induced PR1 expression and basal resistance to a virulent strain of P.syringae. Binds directly to the promoter of the PR1 gene (PubMed:22826500). Acts as positive regulator of innate immunity. Involved in the effector-triggered immunity (ETI) induction of immunity-related gene expression (PubMed:24329768). Mediates osmotic stress signaling in leaf senescence by up-regulating senescence-associated genes (PubMed:18443413). {ECO:0000269\|PubMed:17947243, ECO:0000269\|PubMed:18443413, ECO:0000269\|PubMed:22826500, ECO:0000269\|PubMed:24329768}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_023885011.1	5e-46	protein NTM1-like 9
Refseq	XP_023894735.1	5e-46	protein NTM1-like 9
Swissprot	F4JN35	6e-29	NTL9_ARATH; Protein NTM1-like 9
TrEMBL	A0A2N9H8V1	2e-41	A0A2N9H8V1_FAGSY; Uncharacterized protein
STRING	POPTR_0014s10350.1	3e-30	(Populus trichocarpa)
STRING	AES84472	7e-30	(Medicago truncatula)
STRING	AES84621	7e-30	(Medicago truncatula)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF2065	25	86

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G35580.3	1e-27	NAC transcription factor-like 9

Publications ? help Back to Top
Zheng XY, et al. Spatial and temporal regulation of biosynthesis of the plant immune signal salicylic acid. Proc. Natl. Acad. Sci. U.S.A., 2015. 112(30): p. 9166-73 [PMID:26139525] Guo T, et al. Lamin-like Proteins Negatively Regulate Plant Immunity through NAC WITH TRANSMEMBRANE MOTIF1-LIKE9 and NONEXPRESSOR OF PR GENES1 in Arabidopsis thaliana. Mol Plant, 2017. 10(10): p. 1334-1348 [PMID:28943325]