PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Rutaceae; Aurantioideae; Citrus

Family

MYB

Protein Properties

Length: 317aa MW: 35312.9 Da PI: 7.3869

Description

MYB family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
orange1.1g045434m	genome	ICGC	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Myb_DNA-binding	58.8	1.2e-18	14	61	1	48
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 +g+WT +Ed++lv++++++G g+W++ ++ g++R++k+c++rw +yl orange1.1g045434m 14 KGPWTSDEDQKLVKYIQKHGHGSWRALPKLAGLNRCGKSCRLRWTNYL 61 79********************************************97 PP
2	Myb_DNA-binding	55	1.9e-17	67	112	1	48
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 rg++++eE++ +++++ lG++ W++Ia +++ gRt++++k++w+++l orange1.1g045434m 67 RGKFSQEEEQTILNLHSILGNK-WSAIAGHLP-GRTDNEIKNFWNTHL 112 89******************.*****.**********996 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.10.60	1.2E-25	5	64	IPR009057	Homeodomain-like
PROSITE profile	PS51294	17.687	9	61	IPR017930	Myb domain
SuperFamily	SSF46689	5.99E-32	11	108	IPR009057	Homeodomain-like
SMART	SM00717	6.3E-15	13	63	IPR001005	SANT/Myb domain
Pfam	PF00249	3.8E-17	14	61	IPR001005	SANT/Myb domain
CDD	cd00167	3.87E-11	16	61	No hit	No description
PROSITE profile	PS51294	26.442	62	116	IPR017930	Myb domain
Gene3D	G3DSA:1.10.10.60	9.6E-28	65	117	IPR009057	Homeodomain-like
SMART	SM00717	2.7E-16	66	114	IPR001005	SANT/Myb domain
Pfam	PF00249	5.5E-16	67	112	IPR001005	SANT/Myb domain
CDD	cd00167	2.02E-11	69	112	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009751	Biological Process	response to salicylic acid
GO:0009753	Biological Process	response to jasmonic acid
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 317 aa Download sequence Send to blast
MGRSPCCDES GLKKGPWTSD EDQKLVKYIQ KHGHGSWRAL PKLAGLNRCG KSCRLRWTNY 60 LRPDIKRGKF SQEEEQTILN LHSILGNKWS AIAGHLPGRT DNEIKNFWNT HLKKKLIQMG 120 FDPMTHRPRT DVFSSLPHLI ALANLKELME NHTWEEQAVR LQAEMTKLQY LQYLLQPSSS 180 NSLNNSSSSA FTDIDSINLF NHFHHLLNGI WDLQVPCSYQ TPLNKNSTDN TVHGAEFPVL 240 SQGESFSPKS PWQQLAAASS STPSPPSMVP PPLTESSINN LADACSTSSS YGGSVVAAPS 300 VWPELLLEDP LFHEIA*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1a5j_A	2e-29	12	116	5	108	B-MYB
Search in ModeBase

Expression -- Description ? help Back to Top
Source	Description
Uniprot	DEVELOPMENTAL STAGE: Specifically and transiently expressed in root endodermal cells overlying the early stages of lateral root primordia formation. {ECO:0000269\|PubMed:24902892, ECO:0000269\|PubMed:25482809}.
Uniprot	TISSUE SPECIFICITY: Highly expressed in roots and at lower levels in stems, flowers and siliques. {ECO:0000269\|PubMed:24902892}.

Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcription factor. {ECO:0000250\|UniProtKB:Q9M2D9}.
UniProt	Transcription factor that acts as negative regulator of lateral root (LR) development. Required for normal auxin responses during LR development. May be part of a negative feedback loop stimulated specifically in the endodermis upon LR initiation to ensure that LRs are formed only in the correct place. {ECO:0000269\|PubMed:24902892}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00503	DAP	Transfer from AT5G10280	Download

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by abscisic acid (ABA), auxin and gravity in roots. {ECO:0000269\|PubMed:24902892}.
UniProt	INDUCTION: Induced by gravity in roots. {ECO:0000269\|PubMed:24902892}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AM430933	7e-41	AM430933.2 Vitis vinifera contig VV78X227166.3, whole genome shotgun sequence.
GenBank	AM442163	7e-41	AM442163.1 Vitis vinifera, whole genome shotgun sequence, contig VV78X189718.9, clone ENTAV 115.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006428207.1	0.0	transcription factor MYB93
Refseq	XP_006464255.1	0.0	transcription factor MYB93
Swissprot	Q9S9Z2	1e-103	MYB93_ARATH; Transcription factor MYB93
Swissprot	Q9SBF3	1e-103	MYB92_ARATH; Transcription factor MYB92
TrEMBL	A0A067EMY0	0.0	A0A067EMY0_CITSI; Uncharacterized protein
STRING	XP_006464255.1	0.0	(Citrus sinensis)
STRING	XP_006428207.1	0.0	(Citrus clementina)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM4	28	2646

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G34670.1	2e-96	myb domain protein 93

Link Out ? help Back to Top
Phytozome	orange1.1g045434m

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Gibbs DJ,Coates JC AtMYB93 is an endodermis-specific transcriptional regulator of lateral root development in arabidopsis. Plant Signal Behav, 2014. 9(10): p. e970406 [PMID:25482809]