PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Rutaceae; Aurantioideae; Citrus

Family

MYB

Protein Properties

Length: 536aa MW: 58941.9 Da PI: 8.5889

Description

MYB family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
orange1.1g009391m	genome	ICGC	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Myb_DNA-binding	53.1	7.5e-17	60	106	1	48
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 +g WT+eEde l +av + g++Wk+Ia+ ++ R++ qc +rwqk+l orange1.1g009391m 60 KGGWTPEEDETLRNAVSTFKGKSWKKIAEFFP-DRSEVQCLHRWQKVL 106 688***************************.**********986 PP
2	Myb_DNA-binding	59.1	1e-18	112	158	1	48
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 +g+WT+eEd+++ ++v ++G+ W+ Ia+ ++ gR +kqc++rw+++l orange1.1g009391m 112 KGPWTQEEDDKITELVSKYGPTKWSVIAKSLP-GRIGKQCRERWHNHL 158 79****************************.***********97 PP
3	Myb_DNA-binding	56	8.8e-18	164	207	1	46
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHH CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqk 46 +++WT eE++ l +a++ +G++ W+ Ia+ ++ gRt++++k++w++ orange1.1g009391m 164 KDAWTLEEELALMNAHRIHGNK-WAEIAKVLP-GRTDNSIKNHWNS 207 679*****************.*****.*********96 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51294	15.551	55	106	IPR017930	Myb domain
SMART	SM00717	1.2E-14	59	108	IPR001005	SANT/Myb domain
Pfam	PF00249	1.5E-15	60	106	IPR001005	SANT/Myb domain
SuperFamily	SSF46689	1.94E-15	61	116	IPR009057	Homeodomain-like
Gene3D	G3DSA:1.10.10.60	9.7E-20	62	115	IPR009057	Homeodomain-like
CDD	cd00167	4.71E-13	63	106	No hit	No description
PROSITE profile	PS51294	31.365	107	162	IPR017930	Myb domain
SuperFamily	SSF46689	1.25E-31	109	205	IPR009057	Homeodomain-like
SMART	SM00717	1.0E-17	111	160	IPR001005	SANT/Myb domain
Pfam	PF00249	7.1E-18	112	158	IPR001005	SANT/Myb domain
CDD	cd00167	1.52E-15	114	158	No hit	No description
Gene3D	G3DSA:1.10.10.60	2.0E-27	116	165	IPR009057	Homeodomain-like
SMART	SM00717	1.3E-16	163	211	IPR001005	SANT/Myb domain
PROSITE profile	PS51294	22.781	163	213	IPR017930	Myb domain
Pfam	PF00249	5.9E-16	164	207	IPR001005	SANT/Myb domain
Gene3D	G3DSA:1.10.10.60	1.3E-23	166	213	IPR009057	Homeodomain-like
CDD	cd00167	8.21E-13	166	209	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 536 aa Download sequence Send to blast
MAEVKLEEEC CLENKQLTAA SSSSLSEGSS SAILKSPGVS SPATTSPTHR RTTGPIRRAK 60 GGWTPEEDET LRNAVSTFKG KSWKKIAEFF PDRSEVQCLH RWQKVLNPDL VKGPWTQEED 120 DKITELVSKY GPTKWSVIAK SLPGRIGKQC RERWHNHLNP DIKKDAWTLE EELALMNAHR 180 IHGNKWAEIA KVLPGRTDNS IKNHWNSSLK KKLDFYLATG KLPPVAKSSL QNGTKDTSQS 240 TATENLVCSN KDSDSAAQTS SGTTDIGKPD EEGGKDRLEP SALVPDMATS SSIRPNESMD 300 SEGLECNPES PNIDLTCSES MPRLENCTVN CEFVEDKVTG TQKQVGTPTY GSLYYVPPEL 360 KSFILLDKDT SNRHSVHHDY NSSPITSPIS FFTPPCVKGS GLSSPSPESI LKIAAKTFPY 420 TPSIFRKRKP VSQVQLDANK IGKVDGESGS DRFCLSGKQE SNQNNSKNSR FQDASPSGSI 480 EPTGMTFNAS PPYRLRSKRT AVFKSVERQL EFTSNKEKGD RNANFVKPSV KGTSH*

Sequence ? help Back to Top

Protein Sequence Length: 536 aa Download sequence Send to blast

MAEVKLEEEC CLENKQLTAA SSSSLSEGSS SAILKSPGVS SPATTSPTHR RTTGPIRRAK  60
GGWTPEEDET LRNAVSTFKG KSWKKIAEFF PDRSEVQCLH RWQKVLNPDL VKGPWTQEED  120
DKITELVSKY GPTKWSVIAK SLPGRIGKQC RERWHNHLNP DIKKDAWTLE EELALMNAHR  180
IHGNKWAEIA KVLPGRTDNS IKNHWNSSLK KKLDFYLATG KLPPVAKSSL QNGTKDTSQS  240
TATENLVCSN KDSDSAAQTS SGTTDIGKPD EEGGKDRLEP SALVPDMATS SSIRPNESMD  300
SEGLECNPES PNIDLTCSES MPRLENCTVN CEFVEDKVTG TQKQVGTPTY GSLYYVPPEL  360
KSFILLDKDT SNRHSVHHDY NSSPITSPIS FFTPPCVKGS GLSSPSPESI LKIAAKTFPY  420
TPSIFRKRKP VSQVQLDANK IGKVDGESGS DRFCLSGKQE SNQNNSKNSR FQDASPSGSI  480
EPTGMTFNAS PPYRLRSKRT AVFKSVERQL EFTSNKEKGD RNANFVKPSV KGTSH*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1h88_C	5e-68	59	213	5	159	MYB PROTO-ONCOGENE PROTEIN
1h89_C	5e-68	59	213	5	159	MYB PROTO-ONCOGENE PROTEIN
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Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
Csi.5191	7e-39	callus

Expression -- Description ? help Back to Top
Source	Description
Uniprot	DEVELOPMENTAL STAGE: Expressed both in proliferating and maturing stages of leaves. {ECO:0000269\|PubMed:26069325}.

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that binds 5'-AACGG-3' motifs in gene promoters (By similarity). Transcription repressor that regulates organ growth. Binds to the promoters of G2/M-specific genes and to E2F target genes to prevent their expression in post-mitotic cells and to restrict the time window of their expression in proliferating cells (PubMed:26069325). {ECO:0000250\|UniProtKB:Q94FL9, ECO:0000269\|PubMed:26069325}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00482	DAP	Transfer from AT5G02320	Download

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Slightly induced by ethylene and salicylic acid (SA). {ECO:0000269\|PubMed:16463103}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006429084.1	0.0	transcription factor MYB3R-5
Refseq	XP_006429085.1	0.0	transcription factor MYB3R-5
Refseq	XP_006480818.1	0.0	transcription factor MYB3R-5
Refseq	XP_006480819.1	0.0	transcription factor MYB3R-5
Refseq	XP_006480820.1	0.0	transcription factor MYB3R-5
Refseq	XP_024037722.1	0.0	transcription factor MYB3R-5
Swissprot	Q6R032	1e-174	MB3R5_ARATH; Transcription factor MYB3R-5
TrEMBL	A0A067DRE0	0.0	A0A067DRE0_CITSI; Uncharacterized protein
STRING	XP_006480818.1	0.0	(Citrus sinensis)
STRING	XP_006429084.1	0.0	(Citrus clementina)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM1667	28	87

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G02320.2	1e-165	myb domain protein 3r-5

Link Out ? help Back to Top
Phytozome	orange1.1g009391m

Publications ? help Back to Top
Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Kobayashi K, et al. Transcriptional repression by MYB3R proteins regulates plant organ growth. EMBO J., 2015. 34(15): p. 1992-2007 [PMID:26069325] Chen P, et al. Arabidopsis R1R2R3-Myb proteins are essential for inhibiting cell division in response to DNA damage. Nat Commun, 2017. 8(1): p. 635 [PMID:28935922]