PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Rosoideae; Potentilleae; Fragariinae; Fragaria

Family

HSF

Protein Properties

Length: 509aa MW: 55664.9 Da PI: 4.5469

Description

HSF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
mrna13904.1-v1.0-hybrid	genome	GDR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HSF_DNA-bind	114.8	5.5e-36	39	130	2	102
HHHHHHHHHCTGGGTTTSEESSSSSEEEES-HHHHHHHTHHHHSTT--HHHHHHHHHHTTEEE---SSBTTTTXTTSEEEEESXXX CS HSF_DNA-bind 2 FlkklyeiledeelkeliswsengnsfvvldeeefakkvLpkyFkhsnfaSFvRQLnmYgFkkvkdeekkskskekiweFkhksFk 87 Fl+k+y++++d++++ ++sws ++nsfvv+++ efa+++LpkyFkh+nf+SFvRQLn+YgF+kv+ ++ weF+++ F mrna13904.1-v1.0-hybrid 39 FLSKTYDMVDDPATDPIVSWSPTNNSFVVWNPPEFARDLLPKYFKHNNFSSFVRQLNTYGFRKVDPDR---------WEFANEGFL 115 9******************999*************************************999.........***** PP XXXXXXXXXXXXXXX CS HSF_DNA-bind 88 kgkkellekikrkks 102 +g+k+ll++i+r+k mrna13904.1-v1.0-hybrid 116 RGQKHLLKSINRRKP 130 **********986 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.10.10	6.7E-40	33	123	IPR011991	Winged helix-turn-helix DNA-binding domain
SuperFamily	SSF46785	4.08E-36	35	128	IPR011991	Winged helix-turn-helix DNA-binding domain
SMART	SM00415	1.9E-64	35	128	IPR000232	Heat shock factor (HSF)-type, DNA-binding
Pfam	PF00447	2.0E-32	39	128	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	1.3E-20	39	62	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	1.3E-20	77	89	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PROSITE pattern	PS00434	0	78	102	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	1.3E-20	90	102	IPR000232	Heat shock factor (HSF)-type, DNA-binding

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0009408	Biological Process	response to heat
GO:0005634	Cellular Component	nucleus
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 509 aa Download sequence Send to blast
MVGTSTNPDE STAQTSAAGG SDSAPAPTPL LNSNAPPPFL SKTYDMVDDP ATDPIVSWSP 60 TNNSFVVWNP PEFARDLLPK YFKHNNFSSF VRQLNTYGFR KVDPDRWEFA NEGFLRGQKH 120 LLKSINRRKP AHGHSLQQPQ QPSHGQNSVA ACVEVGKFGL EEEVEMLKRD KNVLMQELIR 180 LRQQQQSTDN QLQTMVQRLQ GMEQRQQQMM SFLAKAVQSP GFLNQFVQQQ NESNRRITEV 240 NKKRRLRQEG IAENERSDTP DGQIVKYQPP MNEAAKAMLR KIMKTNTSSQ LDSFSNHLEN 300 FLLGEGTSSS SAVESGSSSS HASGATLQEV PPTSGHGPFP AISEIESSLK ATNSGEVMRD 360 PFLDMNVLIG AQEAPAVPIS QEVVPEVSQV QGMANGGVIG IPEGNATPEA GVGLIQDMAP 420 EAGDGFIDSP FDFMSLDVDS IPHDDLDALN LWDLLEQSPV PDEMDSTSAE AIPVGNEVQL 480 TENGCDKTQN MDRLTEQMGN LKSNTKGV*

Sequence ? help Back to Top

Protein Sequence Length: 509 aa Download sequence Send to blast

MVGTSTNPDE STAQTSAAGG SDSAPAPTPL LNSNAPPPFL SKTYDMVDDP ATDPIVSWSP  60
TNNSFVVWNP PEFARDLLPK YFKHNNFSSF VRQLNTYGFR KVDPDRWEFA NEGFLRGQKH  120
LLKSINRRKP AHGHSLQQPQ QPSHGQNSVA ACVEVGKFGL EEEVEMLKRD KNVLMQELIR  180
LRQQQQSTDN QLQTMVQRLQ GMEQRQQQMM SFLAKAVQSP GFLNQFVQQQ NESNRRITEV  240
NKKRRLRQEG IAENERSDTP DGQIVKYQPP MNEAAKAMLR KIMKTNTSSQ LDSFSNHLEN  300
FLLGEGTSSS SAVESGSSSS HASGATLQEV PPTSGHGPFP AISEIESSLK ATNSGEVMRD  360
PFLDMNVLIG AQEAPAVPIS QEVVPEVSQV QGMANGGVIG IPEGNATPEA GVGLIQDMAP  420
EAGDGFIDSP FDFMSLDVDS IPHDDLDALN LWDLLEQSPV PDEMDSTSAE AIPVGNEVQL  480
TENGCDKTQN MDRLTEQMGN LKSNTKGV*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5d5u_B	4e-28	19	128	10	129	Heat shock factor protein 1
5d5v_B	4e-28	19	128	10	129	Heat shock factor protein 1
5d5v_D	4e-28	19	128	10	129	Heat shock factor protein 1
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Functional Description ? help Back to Top
Source	Description
UniProt	DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. {ECO:0000250}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	mrna13904.1-v1.0-hybrid

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_004300222.1	0.0	PREDICTED: heat shock factor protein HSF8
Swissprot	Q40152	1e-169	HSF8_SOLLC; Heat shock factor protein HSF8
TrEMBL	A0A1B0VB92	0.0	A0A1B0VB92_FRAVE; Heat shock factor A1d
STRING	XP_004300222.1	0.0	(Fragaria vesca)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF1843	31	69

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G32330.1	1e-130	heat shock transcription factor A1D

Link Out ? help Back to Top
Phytozome	mrna13904.1-v1.0-hybrid

Publications ? help Back to Top
Zhu B, et al. Identification and characterization of a novel heat shock transcription factor gene, GmHsfA1, in soybeans (Glycine max). J. Plant Res., 2006. 119(3): p. 247-56 [PMID:16570125] Cai SY, et al. HsfA1a upregulates melatonin biosynthesis to confer cadmium tolerance in tomato plants. J. Pineal Res., 2017. [PMID:28095626] Zhou J, et al. Heat Shock Factor HsfA1a Is Essential for R Gene-Mediated Nematode Resistance and Triggers H2O2 Production1. Plant Physiol., 2018. 176(3): p. 2456-2471 [PMID:29339397]