PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID maker-scaffold19642-snap-gene-0.3-mRNA-1
Organism
Castanea mollissima
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fagales; Fagaceae; Castanea
Family MYB
Protein Properties Length: 143aa    MW: 16614.1 Da    PI: 11.0959
Description MYB family protein
Gene Model
Gene Model ID Type Source Coding Sequence
maker-scaffold19642-snap-gene-0.3-mRNA-1genomeTHGPView Nucleic Acid
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Myb_DNA-binding44.73.1e-141156146
                                              TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHH CS
                           Myb_DNA-binding  1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqk 46
                                              +g+W +eEde l++ vk++G+++W++I ++  + Rt+k+c++rw +
  maker-scaffold19642-snap-gene-0.3-mRNA-1 11 KGPWKAEEDEVLLNHVKKYGPRDWSSIRSKGLLQRTGKSCRLRWVN 56
                                              79*************************8887799**********87 PP
2Myb_DNA-binding43.57.3e-1467106344
                                               SS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHH CS
                           Myb_DNA-binding   3 rWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrw 44 
                                               +++ eE+   +++ +q+G++ W++Ia +++ gRt++++k++w
  maker-scaffold19642-snap-gene-0.3-mRNA-1  67 KFSVEEERVVIELQAQFGNK-WARIATYLP-GRTDNDVKNFW 106
                                               799*****************.*********.*********** PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5129421.458662IPR017930Myb domain
Gene3DG3DSA:1.10.10.605.2E-22659IPR009057Homeodomain-like
SuperFamilySSF466893.2E-298106IPR009057Homeodomain-like
SMARTSM007176.9E-111060IPR001005SANT/Myb domain
CDDcd001672.94E-101358No hitNo description
PfamPF139211.0E-121464No hitNo description
Gene3DG3DSA:1.10.10.602.4E-1860112IPR009057Homeodomain-like
PROSITE profilePS5129418.31563114IPR017930Myb domain
SMARTSM007174.4E-1264112IPR001005SANT/Myb domain
PfamPF002493.4E-1267106IPR001005SANT/Myb domain
CDDcd001673.66E-967106No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 143 aa     Download sequence    Send to blast
MEVKRNEGIR KGPWKAEEDE VLLNHVKKYG PRDWSSIRSK GLLQRTGKSC RLRWVNKLRP  60
NLKNGCKFSV EEERVVIELQ AQFGNKWARI ATYLPGRTDN DVKNFWSSRQ KRLARILQTS  120
GTANKPQKNK RAVQTCHDVP VSQ
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1h8a_C2e-29611222126MYB TRANSFORMING PROTEIN
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that acts as a positive regulator of male germline development by promoting both gametic cell specification and cell cycle progression (PubMed:15694308, PubMed:15618418, PubMed:19300502, PubMed:21285328). Binds to canonical MYB sites 5'-AACCGTC-3', 5'-AAACCGC-3' and 5'-AACCGT-3' in promoters to trigger the expression of male germline-specific or enriched genes (e.g. MGH3, GEX2 and GCS1), including those required for fertilization (PubMed:21285328, PubMed:19300502). Required for sperm cell specification leading to pollen maturation by activating a germline-specific regulon (PubMed:21285328, PubMed:15694308, PubMed:15618418, PubMed:19300502). Involved in pollen mitosis entry at G2-M transition via the regulation of CYCB1-1, DAZ1 and DAZ2 expression (PubMed:15618418, PubMed:19300502, PubMed:24876252). {ECO:0000269|PubMed:15618418, ECO:0000269|PubMed:15694308, ECO:0000269|PubMed:19300502, ECO:0000269|PubMed:21285328, ECO:0000269|PubMed:24876252}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Repressed by the microRNA 159 (miR159); the production of miR159 is stimulated by the anaphase promoting complex/cyclosome (APC/C) (PubMed:21441434). Activated by ARID1 in male germline cells via specific histone acetylation regulation (e.g. H3K9Ac) (PubMed:25057814). {ECO:0000269|PubMed:21441434, ECO:0000269|PubMed:25057814}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_023927734.11e-101transcription factor DUO1-like
SwissprotA0A178VEK73e-73DUO1_ARATH; Transcription factor DUO1
TrEMBLA0A2I4HDR66e-86A0A2I4HDR6_JUGRE; transcription factor MYB57 isoform X1
STRINGXP_009345055.16e-81(Pyrus x bretschneideri)
STRINGXP_008356546.16e-81(Malus domestica)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF36933164
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G60460.19e-76MYB family protein
Publications ? help Back to Top
  1. Zheng B,He H,Zheng Y,Wu W,McCormick S
    An ARID domain-containing protein within nuclear bodies is required for sperm cell formation in Arabidopsis thaliana.
    PLoS Genet., 2014. 10(7): p. e1004421
    [PMID:25057814]
  2. Peters B, et al.
    A Conserved cis-Regulatory Module Determines Germline Fate through Activation of the Transcription Factor DUO1 Promoter.
    Plant Physiol., 2017. 173(1): p. 280-293
    [PMID:27624837]
  3. Zheng Z, et al.
    Target RNA Secondary Structure Is a Major Determinant of miR159 Efficacy.
    Plant Physiol., 2017. 174(3): p. 1764-1778
    [PMID:28515145]