PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fagales; Fagaceae; Castanea

Family

NAC

Protein Properties

Length: 607aa MW: 69774 Da PI: 5.5413

Description

NAC family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
maker-scaffold14907-augustus-gene-0.3-mRNA-1	genome	THGP	View Nucleic Acid

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	NAM	134	1e-41	58	184	1	128
NAM 1 lppGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLp.kkvkaeekewyfFskr 64 lppG+rF Ptd el+ +yL+kkv++++l+ + i e+++y ++P+ L + k +e+e+yfF++r maker-scaffold14907-augustus-gene-0.3-mRNA-1 58 LPPGYRFCPTDVELIRFYLNKKVSNEPLPP-NQIVETNLYGYNPEFLAaNYRKCGENECYFFTPR 121 79***********************999.77**********9445556899**** PP NAM 65 dkkyatgkrknratksgyWkatgkdkevlskkgelvglkktLvfykgrapkgektdWvmheyrl 128 d+ky +g r+nra+ +gyWkatg dk+++ +++l+g kk Lvf +g+ p+g+kt+W+mhe+r+ maker-scaffold14907-augustus-gene-0.3-mRNA-1 122 DRKYLNGVRPNRAAGDGYWKATGVDKPIIF-NETLIGYKKALVFCQGKPPNGTKTNWIMHEFRV 184 **************************.999**************************97 PP
2	NAM	138.3	4.9e-43	250	375	2	128
NAM 2 ppGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLpkkvka.eekewyfFskrd 65 ppG+rF Ptd+elv +yL+kkv++++l+ + i e+++y ++P+ L +++++ +e e+yfF++rd maker-scaffold14907-augustus-gene-0.3-mRNA-1 250 PPGYRFCPTDDELVRFYLNKKVSNEPLPP-NQIVETNLYLHNPEFLAANYNKcGEYECYFFTPRD 313 9***********************999.77**********9544442777***** PP NAM 66 kkyatgkrknratksgyWkatgkdkevlskkgelvglkktLvfykgrapkgektdWvmheyrl 128 +ky +g+r+nra+ +gyWkatg dk+++ ++ l+g +k Lvfy+g+ap+g+kt+W+mhe+r+ maker-scaffold14907-augustus-gene-0.3-mRNA-1 314 RKYLNGNRPNRAAGDGYWKATGADKHIIF-DEVLIGYRKALVFYRGKAPNGTKTNWIMHEFRV 375 *************************.99***************************97 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF101941	3.14E-52	55	210	IPR003441	NAC domain
PROSITE profile	PS51005	48.764	58	210	IPR003441	NAC domain
Pfam	PF02365	5.6E-22	59	184	IPR003441	NAC domain
SuperFamily	SSF101941	4.58E-53	244	401	IPR003441	NAC domain
PROSITE profile	PS51005	49.736	249	401	IPR003441	NAC domain
Pfam	PF02365	9.7E-24	250	375	IPR003441	NAC domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 607 aa Download sequence Send to blast
PPAQTEALNI IEHCNNTNNI TPLTTPPVVS QDDYDSDVDD LLKEIEDFAS DEFSFDDLPP 60 GYRFCPTDVE LIRFYLNKKV SNEPLPPNQI VETNLYGYNP EFLAANYRKC GENECYFFTP 120 RDRKYLNGVR PNRAAGDGYW KATGVDKPII FNETLIGYKK ALVFCQGKPP NGTKTNWIMH 180 EFRVDNPPRE KRNPGDMRLD DSVLCRIYNK TDPKTKSNRK STWINIRKGM ELEEALLDLF 240 FDTFPFDTFP PGYRFCPTDD ELVRFYLNKK VSNEPLPPNQ IVETNLYLHN PEFLAANYNK 300 CGEYECYFFT PRDRKYLNGN RPNRAAGDGY WKATGADKHI IFDEVLIGYR KALVFYRGKA 360 PNGTKTNWIM HEFRVDTPPR DKRSPGDMKL DDSVLCRIYK KTEKKSTQAH TQDEEVPNST 420 SLPQNEPMEY FEFKDPMAQM IYDHDYMLQS DQNAPSALLE VPQNSNATTL IDMPGFHDPF 480 QARGGSIFET PVQSNQQSFC LPPSLNSAET LNLPSRYQHW SYATNPFKNT SAMQSDYYNY 540 CVYQQASLNN QVSTSMPSPG NDPNMLLILN NQVSTSTPSH QVSPSMPFSS NDPHKRQKLS 600 NDDHSFR

Sequence ? help Back to Top

Protein Sequence Length: 607 aa Download sequence Send to blast

PPAQTEALNI IEHCNNTNNI TPLTTPPVVS QDDYDSDVDD LLKEIEDFAS DEFSFDDLPP  60
GYRFCPTDVE LIRFYLNKKV SNEPLPPNQI VETNLYGYNP EFLAANYRKC GENECYFFTP  120
RDRKYLNGVR PNRAAGDGYW KATGVDKPII FNETLIGYKK ALVFCQGKPP NGTKTNWIMH  180
EFRVDNPPRE KRNPGDMRLD DSVLCRIYNK TDPKTKSNRK STWINIRKGM ELEEALLDLF  240
FDTFPFDTFP PGYRFCPTDD ELVRFYLNKK VSNEPLPPNQ IVETNLYLHN PEFLAANYNK  300
CGEYECYFFT PRDRKYLNGN RPNRAAGDGY WKATGADKHI IFDEVLIGYR KALVFYRGKA  360
PNGTKTNWIM HEFRVDTPPR DKRSPGDMKL DDSVLCRIYK KTEKKSTQAH TQDEEVPNST  420
SLPQNEPMEY FEFKDPMAQM IYDHDYMLQS DQNAPSALLE VPQNSNATTL IDMPGFHDPF  480
QARGGSIFET PVQSNQQSFC LPPSLNSAET LNLPSRYQHW SYATNPFKNT SAMQSDYYNY  540
CVYQQASLNN QVSTSMPSPG NDPNMLLILN NQVSTSTPSH QVSPSMPFSS NDPHKRQKLS  600
NDDHSFR

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1ut4_A	1e-47	58	401	16	171	NO APICAL MERISTEM PROTEIN
1ut4_B	1e-47	58	401	16	171	NO APICAL MERISTEM PROTEIN
1ut7_A	1e-47	58	401	16	171	NO APICAL MERISTEM PROTEIN
1ut7_B	1e-47	58	401	16	171	NO APICAL MERISTEM PROTEIN
3swm_A	1e-47	58	401	19	174	NAC domain-containing protein 19
3swm_B	1e-47	58	401	19	174	NAC domain-containing protein 19
3swm_C	1e-47	58	401	19	174	NAC domain-containing protein 19
3swm_D	1e-47	58	401	19	174	NAC domain-containing protein 19
3swp_A	1e-47	58	401	19	174	NAC domain-containing protein 19
3swp_B	1e-47	58	401	19	174	NAC domain-containing protein 19
3swp_C	1e-47	58	401	19	174	NAC domain-containing protein 19
3swp_D	1e-47	58	401	19	174	NAC domain-containing protein 19
4dul_A	1e-47	58	401	16	171	NAC domain-containing protein 19
4dul_B	1e-47	58	401	16	171	NAC domain-containing protein 19
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor of the NAC family associated with the grain protein content (GPC). Accelerates senescence and increases nutrient remobilization from leaves to developing grains. Sequences of 11 European varieties of H.vulgare tested belongs to the same haplotype while the sequence found in H.spontaneum, an ancestor of the cultivated H.vulgare which has a higher GPC, belongs to an other haplotype. {ECO:0000269\|PubMed:17124321, ECO:0000269\|PubMed:20005003}.
UniProt	Transcription factor that binds DNA motifs 5'-CGT[AG](5N)NACG[ACT][AC][AT][ACG][ACT]-3' and 5'-CACG[ACT][AC][AT][AGT][CT]-3' in target genes promoters. Promotes leaf senescence and reduces fruit yield and sugar content, probably by establishing abscisic acid (ABA) homeostasis. {ECO:0000269\|PubMed:29760199}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Accumulates during age-dependent and dark-induced leaf senescence. {ECO:0000269\|PubMed:29760199}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_017982374.1	1e-72	PREDICTED: NAC domain-containing protein 67
Swissprot	A0SPJ8	6e-50	NAM1_HORVV; NAC transcription factor NAM-1
Swissprot	K4BWV2	3e-50	NAP1_SOLLC; NAC domain-containing protein 1
STRING	XP_008227355.1	7e-71	(Prunus mume)
STRING	EMJ15685	1e-71	(Prunus persica)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF10112	16	42

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G77450.1	7e-52	NAC domain containing protein 32

Publications ? help Back to Top
Uauy C,Distelfeld A,Fahima T,Blechl A,Dubcovsky J A NAC Gene regulating senescence improves grain protein, zinc, and iron content in wheat. Science, 2006. 314(5803): p. 1298-301 [PMID:17124321] Jamar C, et al. NAM-1gene polymorphism and grain protein content in Hordeum. J. Plant Physiol., 2010. 167(6): p. 497-501 [PMID:20005003] Tomato Genome Consortium The tomato genome sequence provides insights into fleshy fruit evolution. Nature, 2012. 485(7400): p. 635-41 [PMID:22660326] Ma X, et al. The NAC Transcription Factor SlNAP2 Regulates Leaf Senescence and Fruit Yield in Tomato. Plant Physiol., 2018. 177(3): p. 1286-1302 [PMID:29760199]