PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fagales; Fagaceae; Castanea

Family

NAC

Protein Properties

Length: 332aa MW: 38174 Da PI: 7.5324

Description

NAC family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
maker-scaffold08294-augustus-gene-0.4-mRNA-1	genome	THGP	View Nucleic Acid

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	NAM	174.5	3e-54	12	141	1	128
NAM 1 lppGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLpk..kvka.eekewyfFs 62 +ppGfrFhPtdeel+ +yL+kkv+ + ++l +vi+evd++k+ePwdL++ ++ + ++ewyfFs maker-scaffold08294-augustus-gene-0.4-mRNA-1 12 VPPGFRFHPTDEELLYYYLRKKVSYEAIDL-DVIREVDLNKLEPWDLKEkcRIGSgPQNEWYFFS 75 69**************************.9***********952444443456** PP NAM 63 krdkkyatgkrknratksgyWkatgkdkevlskkgelvglkktLvfykgrapkgektdWvmheyr 127 ++dkky+tg+r+nrat++g+Wkatg+dk++++++++ +g++ktLvfy+grap+g+ktdW+mheyr maker-scaffold08294-augustus-gene-0.4-mRNA-1 76 HKDKKYPTGTRTNRATTAGFWKATGRDKAIHHSNTKRIGMRKTLVFYTGRAPHGQKTDWIMHEYR 140 **************************************************************9 PP NAM 128 l 128 l maker-scaffold08294-augustus-gene-0.4-mRNA-1 141 L 141 8 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF101941	5.23E-60	3	161	IPR003441	NAC domain
PROSITE profile	PS51005	58.18	12	161	IPR003441	NAC domain
Pfam	PF02365	3.1E-28	13	141	IPR003441	NAC domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003002	Biological Process	regionalization
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0009834	Biological Process	plant-type secondary cell wall biogenesis
GO:0010455	Biological Process	positive regulation of cell fate commitment
GO:0048829	Biological Process	root cap development
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 332 aa Download sequence Send to blast
MMSAAGNGQV TVPPGFRFHP TDEELLYYYL RKKVSYEAID LDVIREVDLN KLEPWDLKEK 60 CRIGSGPQNE WYFFSHKDKK YPTGTRTNRA TTAGFWKATG RDKAIHHSNT KRIGMRKTLV 120 FYTGRAPHGQ KTDWIMHEYR LDDDNAEIQE DGWVVCRVFK KKSHNRGYQL PEVAEEEHLG 180 SLTKASGSAP PLQEPKQNNI QALYDYTTFD GSMHLPQLFS PESVVPPSFI SPMSLNNMDI 240 ECSQNLLRLT TASGCGLMQQ ERYNGDWSFL DKLLASHQTQ MDHHHHHQHQ LPQTKCHPSS 300 LQLADHVGTS THHQKFPFQY LGCETDILKF SK

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1ut4_A	1e-51	9	163	14	167	NO APICAL MERISTEM PROTEIN
1ut4_B	1e-51	9	163	14	167	NO APICAL MERISTEM PROTEIN
1ut7_A	1e-51	9	163	14	167	NO APICAL MERISTEM PROTEIN
1ut7_B	1e-51	9	163	14	167	NO APICAL MERISTEM PROTEIN
3swm_A	2e-51	9	163	17	170	NAC domain-containing protein 19
3swm_B	2e-51	9	163	17	170	NAC domain-containing protein 19
3swm_C	2e-51	9	163	17	170	NAC domain-containing protein 19
3swm_D	2e-51	9	163	17	170	NAC domain-containing protein 19
3swp_A	2e-51	9	163	17	170	NAC domain-containing protein 19
3swp_B	2e-51	9	163	17	170	NAC domain-containing protein 19
3swp_C	2e-51	9	163	17	170	NAC domain-containing protein 19
3swp_D	2e-51	9	163	17	170	NAC domain-containing protein 19
4dul_A	1e-51	9	163	14	167	NAC domain-containing protein 19
4dul_B	1e-51	9	163	14	167	NAC domain-containing protein 19
Search in ModeBase

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	159	163	KKKSH

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription regulator. Together with BRN1 and BRN2, regulates cellular maturation of root cap. Represses stem cell-like divisions in the root cap daughter cells, and thus promotes daughter cell fate. Inhibits expression of its positive regulator FEZ in a feedback loop for controlled switches in cell division plane. Promotes the expression of genes involved in secondary cell walls (SCW) biosynthesis. {ECO:0000269\|PubMed:19081078, ECO:0000269\|PubMed:20197506}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00250	DAP	Transfer from AT1G79580	Download

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By FEZ in oriented-divised root cap stem cells. {ECO:0000269\|PubMed:19081078}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	KR605189	1e-147	KR605189.1 Manihot esculenta NAC transcription factors 51 mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_023894433.1	0.0	protein SOMBRERO
Swissprot	Q9MA17	1e-124	SMB_ARATH; Protein SOMBRERO
TrEMBL	A0A2I4DXD7	0.0	A0A2I4DXD7_JUGRE; protein SOMBRERO-like isoform X1
STRING	VIT_19s0085g01210.t01	0.0	(Vitis vinifera)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF7204	34	47

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G79580.3	1e-116	NAC family protein

Publications ? help Back to Top
Fendrych M, et al. Programmed cell death controlled by ANAC033/SOMBRERO determines root cap organ size in Arabidopsis. Curr. Biol., 2014. 24(9): p. 931-40 [PMID:24726156] Bennett T,van den Toorn A,Willemsen V,Scheres B Precise control of plant stem cell activity through parallel regulatory inputs. Development, 2014. 141(21): p. 4055-64 [PMID:25256342] Karve R,Suárez-Román F,Iyer-Pascuzzi AS The Transcription Factor NIN-LIKE PROTEIN7 Controls Border-Like Cell Release. Plant Physiol., 2016. 171(3): p. 2101-11 [PMID:27221617] Kamiya M, et al. Control of root cap maturation and cell detachment by BEARSKIN transcription factors in Arabidopsis. Development, 2016. 143(21): p. 4063-4072 [PMID:27803060]