PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fagales; Fagaceae; Castanea

Family

WRKY

Protein Properties

Length: 506aa MW: 55031.2 Da PI: 7.4386

Description

WRKY family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
maker-scaffold03895-snap-gene-0.20-mRNA-1	genome	THGP	View Nucleic Acid

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	WRKY	97.8	7.3e-31	168	226	2	59
--SS-EEEEEEE--TT-SS-EEEEEE-ST.T---EEEEEE-SSSTTEEEEEEES--SS- CS WRKY 2 dDgynWrKYGqKevkgsefprsYYrCtsa.gCpvkkkversaedpkvveitYegeHnhe 59 +Dg++WrKYGqK kg+++pr+YYrCt a +Cpv+k+v+r+aed++++++tYeg+Hnh+ maker-scaffold03895-snap-gene-0.20-mRNA-1 168 NDGCQWRKYGQKIAKGNPCPRAYYRCTVApDCPVRKQVQRCAEDTSILITTYEGNHNHP 226 8*************************99**************************7 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:2.20.25.80	3.9E-32	152	228	IPR003657	WRKY domain
SuperFamily	SSF118290	1.7E-27	160	228	IPR003657	WRKY domain
PROSITE profile	PS50811	28.702	162	228	IPR003657	WRKY domain
SMART	SM00774	1.3E-37	167	227	IPR003657	WRKY domain
Pfam	PF03106	6.4E-27	168	226	IPR003657	WRKY domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0006952	Biological Process	defense response
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 506 aa Download sequence Send to blast
MGEVKEENER LKIMLQQIEK DYQSLQLRFF DIFKQETPNN FTESSTPSHD ETEEPELVSL 60 CLGRSPTESK KEEKASNPIK ISTKDEEWKA SLSLGWDSNK FQLSTEIVSN PSPETSLEET 120 KQAEAGETWP PSKTLKTMRN GDDEVSQQTH VKRARVSVRA RCDTPTLNDG CQWRKYGQKI 180 AKGNPCPRAY YRCTVAPDCP VRKQVQRCAE DTSILITTYE GNHNHPLPVT ATAMASTTSA 240 AASMLLSSSS MSKPGLGSTA SIAAAPVPNG LHFNPLDNSR EKQFYLPNSS SPLFPTVTLD 300 LTTSPPSSST PFNRLSSSFA SNPRFPSTSL SFSSSQSNIL PTAWGNGYPS FNSVPYNKTH 360 TGGSLNMGKQ SQEQQLSYQS YLEKYHQASS QETLTDSLAK AIASDASFRS MIAATISSMV 420 GGRPTPSSNQ GGGERLGQNM KWGEPIQAVS TDSLTQNGKA CASSYFNRLA SSPSQTSGLM 480 LLQPPLPLSI SKSTPTSTSA IGDQIN

Sequence ? help Back to Top

Protein Sequence Length: 506 aa Download sequence Send to blast

MGEVKEENER LKIMLQQIEK DYQSLQLRFF DIFKQETPNN FTESSTPSHD ETEEPELVSL  60
CLGRSPTESK KEEKASNPIK ISTKDEEWKA SLSLGWDSNK FQLSTEIVSN PSPETSLEET  120
KQAEAGETWP PSKTLKTMRN GDDEVSQQTH VKRARVSVRA RCDTPTLNDG CQWRKYGQKI  180
AKGNPCPRAY YRCTVAPDCP VRKQVQRCAE DTSILITTYE GNHNHPLPVT ATAMASTTSA  240
AASMLLSSSS MSKPGLGSTA SIAAAPVPNG LHFNPLDNSR EKQFYLPNSS SPLFPTVTLD  300
LTTSPPSSST PFNRLSSSFA SNPRFPSTSL SFSSSQSNIL PTAWGNGYPS FNSVPYNKTH  360
TGGSLNMGKQ SQEQQLSYQS YLEKYHQASS QETLTDSLAK AIASDASFRS MIAATISSMV  420
GGRPTPSSNQ GGGERLGQNM KWGEPIQAVS TDSLTQNGKA CASSYFNRLA SSPSQTSGLM  480
LLQPPLPLSI SKSTPTSTSA IGDQIN

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
2ayd_A	5e-21	154	228	1	74	WRKY transcription factor 1
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator involved in the transcriptional regulation of terpene biosynthesis in glandular trichomes (PubMed:24884371). Binds to the promoter of the linalool synthase TPS5 and promotes TPS5 gene transactivation (PubMed:24884371). In association with WRKY72B, contributes to basal defense against root-knot nematodes (RKNs) and potato aphids, as well as Mi-1-mediated gene-for-gene resistance to these pests (PubMed:20409007). Both WRKY72A and WRKY72B are not required for gene-for-gene resistance mediated by Pto, another tomato R gene (PubMed:20409007). {ECO:0000269\|PubMed:20409007, ECO:0000269\|PubMed:24884371}.
UniProt	Transcription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (By similarity). {ECO:0000250}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by infection with the root-knot nematode (RKN) Meloidogyne incognita and potato aphids. {ECO:0000269\|PubMed:20409007}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_023874522.1	0.0	probable WRKY transcription factor 72
Swissprot	A0A3Q7GFB5	1e-107	WK72A_SOLLC; WRKY transcription factor 72A
Swissprot	Q9LXG8	1e-107	WRK72_ARATH; Probable WRKY transcription factor 72
TrEMBL	A0A2N9HS87	0.0	A0A2N9HS87_FAGSY; Uncharacterized protein
STRING	EOY03394	0.0	(Theobroma cacao)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF650	34	134

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G15130.1	2e-91	WRKY DNA-binding protein 72

Publications ? help Back to Top
Tomato Genome Consortium The tomato genome sequence provides insights into fleshy fruit evolution. Nature, 2012. 485(7400): p. 635-41 [PMID:22660326] Spyropoulou EA,Haring MA,Schuurink RC RNA sequencing on Solanum lycopersicum trichomes identifies transcription factors that activate terpene synthase promoters. BMC Genomics, 2014. 15: p. 402 [PMID:24884371]