PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fagales; Fagaceae; Castanea

Family

Dof

Protein Properties

Length: 317aa MW: 34945.9 Da PI: 6.8251

Description

Dof family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
maker-scaffold00608-augustus-gene-0.31-mRNA-1	genome	THGP	View Nucleic Acid

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-Dof	128.1	2.5e-40	51	111	2	62
zf-Dof 2 kekalkcprCdstntkfCyynnyslsqPryfCkaCrryWtkGGalrnvPvGggrrknkkss 62 +++alkcprCdst+tkfCyynnyslsqPryfCk+CrryWtkGG+lrn+PvGgg+rknkk+s maker-scaffold00608-augustus-gene-0.31-mRNA-1 51 HDQALKCPRCDSTHTKFCYYNNYSLSQPRYFCKTCRRYWTKGGTLRNIPVGGGCRKNKKVS 111 6899******************************************************987 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
ProDom	PD007478	8.0E-29	45	105	IPR003851	Zinc finger, Dof-type
Pfam	PF02701	1.0E-33	52	109	IPR003851	Zinc finger, Dof-type
PROSITE profile	PS50884	29.189	55	109	IPR003851	Zinc finger, Dof-type
PROSITE pattern	PS01361	0	57	93	IPR003851	Zinc finger, Dof-type

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0010067	Biological Process	procambium histogenesis
GO:0010087	Biological Process	phloem or xylem histogenesis
GO:0045893	Biological Process	positive regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 317 aa Download sequence Send to blast
MGLTSLQVCM DSSDWLQGTI NDESGMDSSS PSGDMLTCSR PLIERRLRPP HDQALKCPRC 60 DSTHTKFCYY NNYSLSQPRY FCKTCRRYWT KGGTLRNIPV GGGCRKNKKV SSKKPNDQPN 120 QNHLGSSSSS HNPTDLQLSF PEVQYSQYSN ILGTNGTLGN PTFMEAKYNN NGMLENSIRP 180 IDFMENKLEA IVGNSRNYDF MGNGDHLGMV GGLGDHLSGH SLAPHFGLCS PFGMSNIDGN 240 SGTFMDTCQR LMLPYDHAND QDHNAMDVKP NTKLLSLDWQ DQGCSDAGKD SFAYINGLGS 300 WSGMMNGYGP STTNPLV

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that binds specifically to a 5'-AA[AG]G-3' consensus core sequence (By similarity). Promotes expression (PubMed:19915089). The PEAR proteins (e.g. DOF2.4, DOF5.1, DOF3.2, DOF1.1, DOF5.6 and DOF5.3) activate gene expression that promotes radial growth of protophloem sieve elements (PubMed:30626969). Involved in the regulation of interfascicular cambium formation and vascular tissue development, particularly at a very early stage during inflorescence stem development; promotes both cambium activity and phloem specification, but prevents xylem specification (PubMed:19915089). {ECO:0000250\|UniProtKB:Q9M2U1, ECO:0000269\|PubMed:19915089, ECO:0000269\|PubMed:30626969}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00580	DAP	Transfer from AT5G62940	Download

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	LK022690	1e-126	LK022690.1 Fagus sylvatica partial dag gene for dof zinc finger protein, exons 1-2.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_023900260.1	0.0	dof zinc finger protein DOF5.6
Swissprot	Q9FM03	4e-61	DOF56_ARATH; Dof zinc finger protein DOF5.6
TrEMBL	A0A2N9HGN6	0.0	A0A2N9HGN6_FAGSY; Uncharacterized protein
STRING	EOY20732	1e-173	(Theobroma cacao)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF5092	34	56

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G62940.1	9e-63	Dof family protein

Publications ? help Back to Top
Miyashima S, et al. Mobile PEAR transcription factors integrate positional cues to prime cambial growth. Nature, 2019. 565(7740): p. 490-494 [PMID:30626969]