PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; basal Magnoliophyta; Amborellales; Amborellaceae; Amborella

Family

MIKC_MADS

Protein Properties

Length: 223aa MW: 25650 Da PI: 9.5468

Description

MIKC_MADS family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
evm_27.model.AmTr_v1.0_scaffold00071.203	genome	TAGP	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	SRF-TF	98.5	2.7e-31	9	58	1	50
S---SHHHHHHHHHHHHHHHHHHHHHHHHHHT-EEEEEEE-TTSEEEEEE CS SRF-TF 1 krienksnrqvtfskRrngilKKAeELSvLCdaevaviifsstgklyeys 50 krien++nrqvtf+kRrng+lKKA+ELSvLCdaeva+i+fss+g++yey+ evm_27.model.AmTr_v1.0_scaffold00071.203 9 KRIENTTNRQVTFCKRRNGLLKKAYELSVLCDAEVALIVFSSRGRVYEYA 58 79***********************************************8 PP
2	K-box	114	1.5e-37	75	173	2	100
K-box 2 qkssgksleeakaeslqqelakLkkeienLqreqRhllGedLesLslkeLqqLeqqLekslkkiRskKn 70 ++ss +s +ea+++++qqe++kL+++i+ Lq+ +Rh++G++L+ L++keL+qLe +Le++l++iRskKn evm_27.model.AmTr_v1.0_scaffold00071.203 75 DSSSATSISEANSQYYQQEATKLRQQIQLLQNANRHFMGDGLSALTIKELKQLEGRLERGLTRIRSKKN 143 56778889*********************************************************** PP K-box 71 ellleqieelqkkekelqeenkaLrkklee 100 ell+++ie++q+ke elq++n++Lr+k++e evm_27.model.AmTr_v1.0_scaffold00071.203 144 ELLFAEIEYMQNKEAELQKDNMYLRAKIAE 173 *************************986 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM00432	1.5E-42	1	60	IPR002100	Transcription factor, MADS-box
PROSITE profile	PS50066	33.964	1	61	IPR002100	Transcription factor, MADS-box
SuperFamily	SSF55455	6.02E-33	2	75	IPR002100	Transcription factor, MADS-box
CDD	cd00265	4.98E-44	2	71	No hit	No description
PROSITE pattern	PS00350	0	3	57	IPR002100	Transcription factor, MADS-box
PRINTS	PR00404	9.3E-33	3	23	IPR002100	Transcription factor, MADS-box
Pfam	PF00319	9.8E-27	10	57	IPR002100	Transcription factor, MADS-box
PRINTS	PR00404	9.3E-33	23	38	IPR002100	Transcription factor, MADS-box
PRINTS	PR00404	9.3E-33	38	59	IPR002100	Transcription factor, MADS-box
Pfam	PF01486	2.5E-29	84	171	IPR002487	Transcription factor, K-box
PROSITE profile	PS51297	15.778	87	177	IPR002487	Transcription factor, K-box

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 223 aa Download sequence Send to blast
MGRGKIEIKR IENTTNRQVT FCKRRNGLLK KAYELSVLCD AEVALIVFSS RGRVYEYANN 60 NIKTTIERYK KASADSSSAT SISEANSQYY QQEATKLRQQ IQLLQNANRH FMGDGLSALT 120 IKELKQLEGR LERGLTRIRS KKNELLFAEI EYMQNKEAEL QKDNMYLRAK IAEQDRTQQS 180 NMLPAPEFDA IPTFDSQNYY QVNLMEGAHH YRNQDQTALH LG*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1tqe_P	9e-22	1	80	1	80	Myocyte-specific enhancer factor 2B
1tqe_Q	9e-22	1	80	1	80	Myocyte-specific enhancer factor 2B
1tqe_R	9e-22	1	80	1	80	Myocyte-specific enhancer factor 2B
1tqe_S	9e-22	1	80	1	80	Myocyte-specific enhancer factor 2B
6c9l_A	9e-22	1	80	1	80	Myocyte-specific enhancer factor 2B
6c9l_B	9e-22	1	80	1	80	Myocyte-specific enhancer factor 2B
6c9l_C	9e-22	1	80	1	80	Myocyte-specific enhancer factor 2B
6c9l_D	9e-22	1	80	1	80	Myocyte-specific enhancer factor 2B
6c9l_E	9e-22	1	80	1	80	Myocyte-specific enhancer factor 2B
6c9l_F	9e-22	1	80	1	80	Myocyte-specific enhancer factor 2B
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Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcription factor involved in seed development (PubMed:21447172, Ref.1, PubMed:29853599). Plays a role in seed morphogenesis by promoting the correct development of endotesta cell layer, which directs the further development of the seed coat, the endosperm, and consequently the embryo (Ref.1, PubMed:29853599). {ECO:0000269\|PubMed:21447172, ECO:0000269\|PubMed:29853599, ECO:0000269\|Ref.1}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006858589.1	1e-165	floral homeotic protein AGAMOUS
Swissprot	F6I457	1e-114	AG11C_VITVI; Agamous-like MADS-box protein AGL11
TrEMBL	U5D3A6	1e-163	U5D3A6_AMBTC; Uncharacterized protein
STRING	ERN20056	1e-164	(Amborella trichopoda)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Representative plant	OGRP16	17	761

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G18960.1	3e-96	MIKC_MADS family protein

Link Out ? help Back to Top
Phytozome	evm_27.model.AmTr_v1.0_scaffold00071.203
Entrez Gene	18448466

Publications ? help Back to Top
Jaillon O, et al. The grapevine genome sequence suggests ancestral hexaploidization in major angiosperm phyla. Nature, 2007. 449(7161): p. 463-7 [PMID:17721507] Díaz-Riquelme J,Lijavetzky D,Martínez-Zapater JM,Carmona MJ Genome-wide analysis of MIKCC-type MADS box genes in grapevine. Plant Physiol., 2009. 149(1): p. 354-69 [PMID:18997115] Mejía N, et al. Molecular, genetic and transcriptional evidence for a role of VvAGL11 in stenospermocarpic seedlessness in grapevine. BMC Plant Biol., 2011. 11: p. 57 [PMID:21447172] Amborella Genome Project The Amborella genome and the evolution of flowering plants. Science, 2013. 342(6165): p. 1241089 [PMID:24357323] Grimplet J,Martínez-Zapater JM,Carmona MJ Structural and functional annotation of the MADS-box transcription factor family in grapevine. BMC Genomics, 2016. 17: p. 80 [PMID:26818751] Malabarba J, et al. The MADS-box gene Agamous-like 11 is essential for seed morphogenesis in grapevine. J. Exp. Bot., 2017. 68(7): p. 1493-1506 [PMID:28369525] Royo C, et al. The Major Origin of Seedless Grapes Is Associated with a Missense Mutation in the MADS-Box Gene VviAGL11. Plant Physiol., 2018. 177(3): p. 1234-1253 [PMID:29853599]